hu.MAP 2.0: Complex View
Human Protein Complex Map
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Complex: HuMAP2_02526
Confidence: Medium
Proteins| Genename | Protein Name | Links |
|---|---|---|
| ARHGAP35 | Rho GTPase-activating protein 35 (Glucocorticoid receptor DNA-binding factor 1) (Glucocorticoid receptor repression factor 1) (GRF-1) (Rho GAP p190A) (p190-A) | UniProt NCBI |
| SERPINB2 | Plasminogen activator inhibitor 2 (PAI-2) (Monocyte Arg-serpin) (Placental plasminogen activator inhibitor) (Serpin B2) (Urokinase inhibitor) | UniProt NCBI |
| PLAT | Tissue-type plasminogen activator (t-PA) (t-plasminogen activator) (tPA) (EC 3.4.21.68) (Alteplase) (Reteplase) [Cleaved into: Tissue-type plasminogen activator chain A; Tissue-type plasminogen activator chain B] | UniProt NCBI |
| ANLN | Anillin | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| WP:WP272 | 0.000352218401684 | 0.5 | SERPINB2 PLAT | Blood Clotting Cascade |
| REAC:R-HSA-75205 | 0.000663071622452 | 0.5 | SERPINB2 PLAT | Dissolution of Fibrin Clot |
| KEGG:04610 | 0.00401698930658 | 0.5 | SERPINB2 PLAT | Complement and coagulation cascades |
| WP:WP615 | 0.00652808434915 | 0.5 | SERPINB2 PLAT | Senescence and Autophagy in Cancer |
Edges
| Protein 1 | Protein 2 | Score | Precision | Evidence |
|---|---|---|---|---|
| SERPINB2 | PLAT | 0.175 | 0.434 | bioplex (SERPINB2) bioplex_WMM |
| SERPINB2 | ARHGAP35 | 0.055 | 0.305 | bioplex (SERPINB2) bioplex_WMM |
| ARHGAP35 | ANLN | 0.02 | 0.186 | fraction |
| ARHGAP35 | PLAT | 0.007 | 0.011 | bioplex_WMM WMM_only |
Images
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Complex HuMAP2_02526 has an average edge precision of 0.234 which is ranked 5629 out of all 6965 complexes.
Related Complexes
| Genename | Complexes |
|---|---|
| ARHGAP35 | HuMAP2_02526 HuMAP2_03486 HuMAP2_05150 |
| SERPINB2 | HuMAP2_02526 HuMAP2_05150 |
| PLAT | HuMAP2_02526 HuMAP2_05150 |
| ANLN | HuMAP2_02526 HuMAP2_04295 |