hu.MAP 2.0: Complex View
Human Protein Complex Map
Search for a protein
Complex: HuMAP2_02530
Confidence: Medium
Proteins| Genename | Protein Name | Links |
|---|---|---|
| CDK1 | Cyclin-dependent kinase 1 (CDK1) (EC 2.7.11.22) (EC 2.7.11.23) (Cell division control protein 2 homolog) (Cell division protein kinase 1) (p34 protein kinase) | UniProt NCBI |
| CKS1B | Cyclin-dependent kinases regulatory subunit 1 (CKS-1) | UniProt NCBI |
| SCAPER | S phase cyclin A-associated protein in the endoplasmic reticulum (S phase cyclin A-associated protein in the ER) (Zinc finger protein 291) | UniProt NCBI |
| MCIDAS | Multicilin (Multiciliate differentiation and DNA synthesis-associated cell cycle protein) (McIdas protein) (Protein Idas) | UniProt NCBI |
| CCNA2 | Cyclin-A2 (Cyclin-A) (Cyclin A) | UniProt NCBI |
| PHF8 | Histone lysine demethylase PHF8 (EC 1.14.11.27) (PHD finger protein 8) | UniProt NCBI |
| ORC1 | Origin recognition complex subunit 1 (Replication control protein 1) | UniProt NCBI |
| TRIM49 | Tripartite motif-containing protein 49 (RING finger protein 18) (Testis-specific RING-finger protein) | UniProt NCBI |
| CCDC146 | Coiled-coil domain-containing protein 146 | UniProt NCBI |
| CCNB1 | G2/mitotic-specific cyclin-B1 | UniProt NCBI |
| PKMYT1 | Membrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase (EC 2.7.11.1) (Myt1 kinase) | UniProt NCBI |
| SKP2 | S-phase kinase-associated protein 2 (Cyclin-A/CDK2-associated protein p45) (F-box protein Skp2) (F-box/LRR-repeat protein 1) (p45skp2) | UniProt NCBI |
| TICRR | Treslin (TopBP1-interacting checkpoint and replication regulator) (TopBP1-interacting, replication-stimulating protein) | UniProt NCBI |
| RBL2 | Retinoblastoma-like protein 2 (130 kDa retinoblastoma-associated protein) (p130) (Retinoblastoma-related protein 2) (RBR-2) (pRb2) | UniProt NCBI |
| CREBBP | CREB-binding protein (EC 2.3.1.48) | UniProt NCBI |
| CKS2 | Cyclin-dependent kinases regulatory subunit 2 (CKS-2) | UniProt NCBI |
| CDT1 | DNA replication factor Cdt1 (Double parked homolog) (DUP) | UniProt NCBI |
| CCNA1 | Cyclin-A1 | UniProt NCBI |
| CCNB2 | G2/mitotic-specific cyclin-B2 | UniProt NCBI |
| MTMR1 | Myotubularin-related protein 1 (Phosphatidylinositol-3,5-bisphosphate 3-phosphatase) (EC 3.1.3.95) (Phosphatidylinositol-3-phosphate phosphatase) (EC 3.1.3.64) | UniProt NCBI |
| GMNN | Geminin | UniProt NCBI |
| RBL1 | Retinoblastoma-like protein 1 (107 kDa retinoblastoma-associated protein) (p107) (pRb1) | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| KEGG:04110 | 2.15346930357e-16 | 0.5 | RBL1 CREBBP SKP2 ORC1 CCNB2 RBL2 CCNA1 CDK1 PKMYT1 CCNB1 CCNA2 | Cell cycle |
| REAC:R-HSA-69206 | 2.5181531925e-15 | 0.5 | CDT1 GMNN ORC1 RBL2 CCNA1 CDK1 SKP2 CCNB1 CKS1B RBL1 CCNA2 | G1/S Transition |
| REAC:R-HSA-453279 | 1.0128564234e-14 | 0.5 | CDT1 GMNN ORC1 RBL2 CCNA1 CDK1 SKP2 CCNB1 CKS1B RBL1 CCNA2 | Mitotic G1-G1/S phases |
| WP:WP179 | 2.49331271015e-14 | 0.454545454545 | RBL1 SKP2 ORC1 CCNB2 RBL2 CCNA1 CDK1 PKMYT1 CCNB1 CCNA2 | Cell Cycle |
| GO:0000278 | 4.34067804343e-13 | 0.772727272727 | CDT1 CKS2 GMNN PKMYT1 ORC1 TICRR PHF8 CCNB2 RBL2 CCNA1 CDK1 SKP2 CCNB1 CKS1B RBL1 CCNA2 MCIDAS | mitotic cell cycle |
| REAC:R-HSA-69278 | 8.87827845385e-12 | 0.590909090909 | CDT1 GMNN PKMYT1 ORC1 CCNB2 RBL2 CCNA1 CDK1 SKP2 CCNB1 CKS1B RBL1 CCNA2 | Cell Cycle, Mitotic |
| GO:0044772 | 9.88695630407e-12 | 0.636363636364 | CDT1 GMNN ORC1 TICRR CCNB2 RBL2 CCNA1 CDK1 SKP2 PKMYT1 CCNB1 RBL1 CCNA2 PHF8 | mitotic cell cycle phase transition |
| GO:0044770 | 2.41318594066e-11 | 0.636363636364 | CDT1 GMNN ORC1 TICRR CCNB2 RBL2 CCNA1 CDK1 SKP2 PKMYT1 CCNB1 RBL1 CCNA2 PHF8 | cell cycle phase transition |
| GO:0051726 | 7.3594674748e-11 | 0.727272727273 | CDT1 CKS2 GMNN PKMYT1 ORC1 TICRR CCNB2 RBL2 CCNA1 CDK1 SKP2 CCNB1 CKS1B RBL1 CCNA2 MCIDAS | regulation of cell cycle |
| REAC:R-HSA-1640170 | 8.95356442832e-11 | 0.590909090909 | CDT1 GMNN PKMYT1 ORC1 CCNB2 RBL2 CCNA1 CDK1 SKP2 CCNB1 CKS1B RBL1 CCNA2 | Cell Cycle |
| GO:0044843 | 1.2140823028e-10 | 0.5 | CDT1 SKP2 ORC1 RBL2 CCNA1 PHF8 GMNN CCNB1 RBL1 CCNA2 CDK1 | cell cycle G1/S phase transition |
| REAC:R-HSA-69273 | 2.28002587677e-10 | 0.272727272727 | CCNB2 CCNA1 CDK1 PKMYT1 CCNB1 CCNA2 | Cyclin A/B1/B2 associated events during G2/M transition |
| REAC:R-HSA-69205 | 4.83683504218e-10 | 0.272727272727 | CDT1 RBL1 ORC1 RBL2 CCNA1 CDK1 | G1/S-Specific Transcription |
| GO:0007049 | 7.7494055185e-10 | 0.772727272727 | CDT1 CKS2 GMNN PKMYT1 ORC1 TICRR PHF8 CCNB2 RBL2 CCNA1 CDK1 SKP2 CCNB1 CKS1B RBL1 CCNA2 MCIDAS | cell cycle |
| GO:0000307 | 1.73659652734e-09 | 0.318181818182 | CKS2 CCNB2 CCNA1 CDK1 CCNB1 CKS1B CCNA2 | cyclin-dependent protein kinase holoenzyme complex |
| WP:WP2446 | 2.1737947833e-09 | 0.318181818182 | CDT1 ORC1 CCNB2 SKP2 CDK1 CCNB1 CCNA2 | Retinoblastoma Gene in Cancer |
| GO:1903047 | 3.34546945172e-09 | 0.636363636364 | CDT1 GMNN ORC1 TICRR CCNB2 RBL2 CCNA1 CDK1 SKP2 PKMYT1 CCNB1 RBL1 CCNA2 PHF8 | mitotic cell cycle process |
| GO:0000082 | 4.49629378065e-09 | 0.454545454545 | CDT1 SKP2 ORC1 RBL2 CCNA1 PHF8 CCNB1 GMNN RBL1 CDK1 | G1/S transition of mitotic cell cycle |
| REAC:R-HSA-69478 | 4.74151463579e-09 | 0.181818181818 | PKMYT1 CCNB1 CDK1 CCNB2 | G2/M DNA replication checkpoint |
| REAC:R-HSA-6791312 | 1.54668842396e-08 | 0.272727272727 | RBL1 RBL2 CCNA1 CDK1 CCNB1 CCNA2 | TP53 Regulates Transcription of Cell Cycle Genes |
| KEGG:04218 | 6.11752754143e-08 | 0.318181818182 | RBL1 CCNB2 RBL2 CCNA1 CDK1 CCNB1 CCNA2 | Cellular senescence |
| KEGG:04914 | 8.43802203619e-08 | 0.272727272727 | CCNB2 CCNA1 CDK1 PKMYT1 CCNB1 CCNA2 | Progesterone-mediated oocyte maturation |
| REAC:R-HSA-1538133 | 9.07155809821e-08 | 0.227272727273 | CCNA1 RBL2 RBL1 CCNA2 CDK1 | G0 and Early G1 |
| CORUM:6954 | 9.45004101862e-08 | 0.136363636364 | CDT1 MCIDAS GMNN | Idas-Geminin-Cdt1 complex |
| KEGG:05203 | 3.75225266438e-07 | 0.318181818182 | RBL1 SKP2 RBL2 CCNA1 CDK1 CREBBP CCNA2 | Viral carcinogenesis |
| GO:1902554 | 4.48990425568e-07 | 0.318181818182 | CKS2 CCNB2 CCNA1 CDK1 CCNB1 CKS1B CCNA2 | serine/threonine protein kinase complex |
| REAC:R-HSA-69242 | 5.48753780208e-07 | 0.318181818182 | CDT1 SKP2 ORC1 RBL2 CCNA1 CKS1B CCNA2 | S Phase |
| GO:0016538 | 5.56485855211e-07 | 0.272727272727 | CKS2 CCNB2 CCNA1 CCNB1 CKS1B CCNA2 | cyclin-dependent protein serine/threonine kinase regulator activity |
| REAC:R-HSA-170145 | 7.43939399338e-07 | 0.136363636364 | CCNA1 CCNA2 CDK1 | Phosphorylation of proteins involved in the G2/M transition by Cyclin A:Cdc2 complexes |
| GO:0022402 | 1.13802408273e-06 | 0.636363636364 | CDT1 GMNN ORC1 TICRR CCNB2 RBL2 CCNA1 CDK1 SKP2 PKMYT1 CCNB1 RBL1 CCNA2 PHF8 | cell cycle process |
| GO:1902911 | 1.56439082846e-06 | 0.318181818182 | CKS2 CCNB2 CCNA1 CDK1 CCNB1 CKS1B CCNA2 | protein kinase complex |
| REAC:R-HSA-1362300 | 1.70763788571e-06 | 0.181818181818 | RBL1 RBL2 CCNA2 CDK1 | Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1 |
| CORUM:310 | 1.88458749749e-06 | 0.136363636364 | CCNB1 CDK1 CCNB2 | Cell cycle kinase complex CDC2 |
| GO:0007346 | 1.93918875418e-06 | 0.5 | CDT1 CKS2 RBL1 PKMYT1 ORC1 TICRR RBL2 CDK1 CCNB1 CKS1B MCIDAS | regulation of mitotic cell cycle |
| REAC:R-HSA-6804114 | 2.86553188171e-06 | 0.181818181818 | CCNB1 RBL1 CDK1 RBL2 | TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest |
| REAC:R-HSA-69306 | 5.77572941887e-06 | 0.272727272727 | CDT1 CCNA1 ORC1 SKP2 GMNN CCNA2 | DNA Replication |
| REAC:R-HSA-68949 | 1.40294429797e-05 | 0.227272727273 | CDT1 ORC1 CCNA2 SKP2 CCNA1 | Orc1 removal from chromatin |
| REAC:R-HSA-2980767 | 2.5938355272e-05 | 0.136363636364 | CCNB1 CDK1 CCNB2 | Activation of NIMA Kinases NEK9, NEK6, NEK7 |
| CORUM:1005 | 2.67696029845e-05 | 0.136363636364 | CCNB1 CCNA2 CDK1 | RC complex during G2/M-phase of cell cycle |
| REAC:R-HSA-69202 | 2.90940660488e-05 | 0.227272727273 | CKS1B RBL2 CCNA2 SKP2 CCNA1 | Cyclin E associated events during G1/S transition |
| GO:0000086 | 3.08132093138e-05 | 0.363636363636 | ORC1 TICRR CCNB2 SKP2 CDK1 CCNB1 PKMYT1 CCNA2 | G2/M transition of mitotic cell cycle |
| KEGG:04068 | 3.2288670947e-05 | 0.227272727273 | CCNB1 RBL2 CCNB2 CREBBP SKP2 | FoxO signaling pathway |
| REAC:R-HSA-69620 | 3.24633093971e-05 | 0.318181818182 | ORC1 CCNB2 CCNA1 CDK1 PKMYT1 CCNB1 CCNA2 | Cell Cycle Checkpoints |
| REAC:R-HSA-69656 | 3.2855746006e-05 | 0.227272727273 | CKS1B RBL2 CCNA2 SKP2 CCNA1 | Cyclin A:Cdk2-associated events at S phase entry |
| REAC:R-HSA-453276 | 3.48759355595e-05 | 0.227272727273 | CCNA1 CCNB1 CCNA2 SKP2 CDK1 | Regulation of mitotic cell cycle |
| REAC:R-HSA-174143 | 3.48759355595e-05 | 0.227272727273 | CCNA1 CCNB1 CCNA2 SKP2 CDK1 | APC/C-mediated degradation of cell cycle proteins |
| REAC:R-HSA-69052 | 4.39645120569e-05 | 0.227272727273 | CDT1 ORC1 CCNA2 SKP2 CCNA1 | Switching of origins to a post-replicative state |
| GO:0044839 | 5.68578997489e-05 | 0.363636363636 | ORC1 TICRR CCNB2 SKP2 CDK1 CCNB1 PKMYT1 CCNA2 | cell cycle G2/M phase transition |
| REAC:R-HSA-113507 | 6.21329704351e-05 | 0.136363636364 | CCNB1 CDK1 ORC1 | E2F-enabled inhibition of pre-replication complex formation |
| WP:WP366 | 6.53998698817e-05 | 0.227272727273 | RBL1 RBL2 CDK1 CREBBP CCNB2 | TGF-beta Signaling Pathway |
| REAC:R-HSA-69275 | 6.66784584014e-05 | 0.272727272727 | CCNB2 CCNA1 CDK1 PKMYT1 CCNB1 CCNA2 | G2/M Transition |
| CORUM:5557 | 7.03650054247e-05 | 0.0909090909091 | CCNA2 CDK1 | CDC2-CCNA2 complex |
| CORUM:6140 | 7.03650054247e-05 | 0.0909090909091 | CDT1 GMNN | Cdt1-Geminin complex |
| CORUM:5542 | 7.03650054247e-05 | 0.0909090909091 | CDK1 CCNB2 | CCNB2-CDC2 complex |
| CORUM:5543 | 7.03650054247e-05 | 0.0909090909091 | CCNB1 CDK1 | CCNB1-CDC2 complex |
| CORUM:5550 | 7.03650054247e-05 | 0.0909090909091 | CCNB1 CDK1 | CDK1-CCNB1-CCNF complex |
| REAC:R-HSA-453274 | 7.09298727755e-05 | 0.272727272727 | CCNB2 CCNA1 CDK1 PKMYT1 CCNB1 CCNA2 | Mitotic G2-G2/M phases |
| REAC:R-HSA-69236 | 0.000102409773647 | 0.181818181818 | CKS1B RBL1 RBL2 SKP2 | G1 Phase |
| REAC:R-HSA-69231 | 0.000102409773647 | 0.181818181818 | CKS1B RBL1 RBL2 SKP2 | Cyclin D associated events in G1 |
| REAC:R-HSA-3700989 | 0.000120011824618 | 0.318181818182 | RBL1 RBL2 CCNA1 CDK1 CREBBP CCNB1 CCNA2 | Transcriptional Regulation by TP53 |
| REAC:R-HSA-2514853 | 0.000121813446957 | 0.136363636364 | CCNB1 CDK1 CCNB2 | Condensation of Prometaphase Chromosomes |
| WP:WP45 | 0.000151429503818 | 0.181818181818 | CCNA1 ORC1 CDK1 CCNB1 | G1 to S cell cycle control |
| REAC:R-HSA-69239 | 0.000180259012144 | 0.227272727273 | CDT1 ORC1 CCNA2 SKP2 CCNA1 | Synthesis of DNA |
| REAC:R-HSA-162658 | 0.00021073942775 | 0.136363636364 | CCNB1 CDK1 CCNB2 | Golgi Cisternae Pericentriolar Stack Reorganization |
| CORUM:5551 | 0.000210906015454 | 0.0909090909091 | CCNB1 CDK1 | CDC2-CCNB1-PTCH1 complex |
| CORUM:1661 | 0.000210906015454 | 0.0909090909091 | RBL1 CCNA2 | E2F4-p107-cyclinA complex |
| CORUM:243 | 0.000210906015454 | 0.0909090909091 | CCNB1 CDK1 | RalBP1-CDC2-CCNB1 complex |
| CORUM:5559 | 0.000210906015454 | 0.0909090909091 | CCNA2 CDK1 | CDC2-CCNA2-CDK2 complex |
| CORUM:5144 | 0.000210906015454 | 0.0909090909091 | RBL1 CCNA2 | E2F1-p107-cyclinA complex |
| HP:0011267 | 0.000297699514029 | 0.136363636364 | CDT1 ORC1 GMNN | Microtia, third degree |
| HP:0009892 | 0.000297699514029 | 0.136363636364 | CDT1 ORC1 GMNN | Anotia |
| HP:0009939 | 0.000408945143356 | 0.136363636364 | CDT1 ORC1 GMNN | Mandibular aplasia |
| REAC:R-HSA-187577 | 0.000409617039093 | 0.181818181818 | CKS1B CCNA2 SKP2 CCNA1 | SCF(Skp2)-mediated degradation of p27/p21 |
| REAC:R-HSA-156711 | 0.000411453285932 | 0.136363636364 | CCNB1 CCNB2 PKMYT1 | Polo-like kinase mediated events |
| CORUM:5546 | 0.000421434390997 | 0.0909090909091 | CCNB1 CDK1 | CDC2-PCNA-CCNB1-GADD45G complex |
| CORUM:5545 | 0.000421434390997 | 0.0909090909091 | CCNB1 CDK1 | CDC2-PCNA-CCNB1-GADD45B complex |
| CORUM:5544 | 0.000421434390997 | 0.0909090909091 | CCNB1 CDK1 | CDC2-PCNA-CCNB1-GADD45A complex |
| CORUM:2210 | 0.000421434390997 | 0.0909090909091 | GMNN ORC1 | BRCA1-IRIS-pre-replication complex |
| GO:1901991 | 0.00047526862936 | 0.318181818182 | CDT1 RBL1 ORC1 RBL2 CDK1 CCNB1 TICRR | negative regulation of mitotic cell cycle phase transition |
| CORUM:3036 | 0.00070176185411 | 0.0909090909091 | CKS1B SKP2 | Ubiquitin E3 ligase (SKP1A, SKP2, CUL1, CKS1B, RBX1) |
| GO:1901988 | 0.000738133457327 | 0.318181818182 | CDT1 RBL1 ORC1 RBL2 CDK1 CCNB1 TICRR | negative regulation of cell cycle phase transition |
| KEGG:04114 | 0.000942886092832 | 0.181818181818 | PKMYT1 CCNB1 CDK1 CCNB2 | Oocyte meiosis |
| REAC:R-HSA-69481 | 0.00100176942996 | 0.227272727273 | PKMYT1 CCNB1 ORC1 CDK1 CCNB2 | G2/M Checkpoints |
| REAC:R-HSA-176409 | 0.00102063749336 | 0.181818181818 | CCNA1 CCNB1 CCNA2 CDK1 | APC/C:Cdc20 mediated degradation of mitotic proteins |
| CORUM:6444 | 0.00105170048742 | 0.0909090909091 | RBL1 RBL2 | SMAR1-HDAC1-SIN3A-SIN3B-p107-p130 repressor complex |
| REAC:R-HSA-176814 | 0.00107709443273 | 0.181818181818 | CCNA1 CCNB1 CCNA2 CDK1 | Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins |
| GO:0061695 | 0.00108149476334 | 0.318181818182 | CKS2 CCNB2 CCNA1 CDK1 CCNB1 CKS1B CCNA2 | transferase complex, transferring phosphorus-containing groups |
| HP:0006443 | 0.00112338720824 | 0.136363636364 | CDT1 ORC1 GMNN | Patellar aplasia |
| HP:0100783 | 0.00112338720824 | 0.136363636364 | CDT1 ORC1 GMNN | Breast aplasia |
| REAC:R-HSA-113510 | 0.00112501635454 | 0.136363636364 | CCNB1 CDK1 ORC1 | E2F mediated regulation of DNA replication |
| REAC:R-HSA-176408 | 0.00132632142248 | 0.181818181818 | CCNA1 CCNB1 CCNA2 CDK1 | Regulation of APC/C activators between G1/S and early anaphase |
| HP:0006660 | 0.00167569702991 | 0.136363636364 | CDT1 ORC1 GMNN | Aplastic clavicle |
| GO:0019887 | 0.00171658147759 | 0.272727272727 | CKS2 CCNB2 CCNA1 CCNB1 CKS1B CCNA2 | protein kinase regulator activity |
| CORUM:0000000 | 0.00177569830655 | 0.636363636364 | CDT1 MCIDAS CREBBP GMNN ORC1 CCNB2 RBL2 CCNA1 CDK1 SKP2 CCNB1 CKS1B RBL1 CCNA2 | CORUM root |
| CORUM:3015 | 0.00195966139443 | 0.0909090909091 | CKS1B SKP2 | p27-cyclinE-Cdk2 - Ubiquitin E3 ligase (SKP1A, SKP2, CUL1, CKS1B, RBX1) complex |
| GO:0031570 | 0.0020417190637 | 0.272727272727 | CDT1 ORC1 RBL2 CDK1 CCNB1 TICRR | DNA integrity checkpoint |
| WP:WP466 | 0.00233297905249 | 0.136363636364 | CDT1 ORC1 GMNN | DNA Replication |
| HP:0002098 | 0.00240701322648 | 0.227272727273 | CDT1 ORC1 MCIDAS CREBBP GMNN | Respiratory distress |
| KEGG:05200 | 0.00247169999845 | 0.272727272727 | CKS2 SKP2 CCNA1 CREBBP CKS1B CCNA2 | Pathways in cancer |
| HP:0003042 | 0.00258687726063 | 0.181818181818 | CDT1 ORC1 CREBBP GMNN | Elbow dislocation |
| HP:0003045 | 0.00258687726063 | 0.181818181818 | CDT1 ORC1 CREBBP GMNN | Abnormal patella morphology |
| GO:0000079 | 0.00263753528018 | 0.227272727273 | PKMYT1 CCNA1 CCNB1 CCNA2 CCNB2 | regulation of cyclin-dependent protein serine/threonine kinase activity |
| GO:0007093 | 0.00284550909656 | 0.272727272727 | CDT1 ORC1 RBL2 CDK1 CCNB1 TICRR | mitotic cell cycle checkpoint |
| GO:1904029 | 0.00325394177984 | 0.227272727273 | PKMYT1 CCNA1 CCNB1 CCNA2 CCNB2 | regulation of cyclin-dependent protein kinase activity |
| REAC:R-HSA-3301854 | 0.00358891211645 | 0.136363636364 | CCNB1 CDK1 CCNB2 | Nuclear Pore Complex (NPC) Disassembly |
| HP:0000064 | 0.00377684061882 | 0.136363636364 | CDT1 ORC1 GMNN | Hypoplastic labia minora |
| GO:0045930 | 0.00382296474044 | 0.318181818182 | CDT1 RBL1 ORC1 RBL2 CDK1 CCNB1 TICRR | negative regulation of mitotic cell cycle |
| REAC:R-HSA-68962 | 0.00394402661231 | 0.136363636364 | CDT1 ORC1 GMNN | Activation of the pre-replicative complex |
| HP:0030310 | 0.00401819715938 | 0.181818181818 | CDT1 ORC1 CREBBP GMNN | Upper extremity joint dislocation |
| GO:0019207 | 0.00420108258657 | 0.272727272727 | CKS2 CCNB2 CCNA1 CCNB1 CKS1B CCNA2 | kinase regulator activity |
| HP:0000060 | 0.00433921112909 | 0.136363636364 | CDT1 ORC1 GMNN | Clitoral hypoplasia |
| HP:0000039 | 0.00433921112909 | 0.136363636364 | CDT1 ORC1 GMNN | Epispadias |
| HP:0040255 | 0.00433921112909 | 0.136363636364 | CDT1 ORC1 GMNN | Aplasia/Hypoplasia of the clitoris |
| KEGG:05165 | 0.00434069345003 | 0.227272727273 | CCNA1 RBL1 CCNA2 CREBBP RBL2 | Human papillomavirus infection |
| REAC:R-HSA-6804757 | 0.00472219367534 | 0.136363636364 | CCNA1 CCNA2 CDK1 | Regulation of TP53 Degradation |
| GO:0061575 | 0.00487641079113 | 0.136363636364 | CKS1B CKS2 CCNB1 | cyclin-dependent protein serine/threonine kinase activator activity |
| REAC:R-HSA-6806003 | 0.0051465559385 | 0.136363636364 | CCNA1 CCNA2 CDK1 | Regulation of TP53 Expression and Degradation |
| MIRNA:hsa-miR-193b-3p | 0.00538092309259 | 0.363636363636 | CDT1 RBL1 TICRR PHF8 GMNN PKMYT1 CCNA2 CDK1 | hsa-miR-193b-3p |
| REAC:R-HSA-68911 | 0.00552450821321 | 0.0909090909091 | CCNA1 CCNA2 | G2 Phase |
| HPA:008020_23 | 0.00591061203617 | 0.227272727273 | CKS1B ORC1 PHF8 CKS2 CDT1 | cerebral cortex; glial cells[Approved,High] |
| GO:0010948 | 0.00595956729471 | 0.318181818182 | CDT1 RBL1 ORC1 RBL2 CDK1 CCNB1 TICRR | negative regulation of cell cycle process |
| KEGG:04115 | 0.00621796795782 | 0.136363636364 | CCNB1 CDK1 CCNB2 | p53 signaling pathway |
| HP:0012880 | 0.00798835940696 | 0.136363636364 | CDT1 ORC1 GMNN | Abnormality of the labia minora |
| REAC:R-HSA-176417 | 0.00827934426264 | 0.0909090909091 | CCNB1 CDK1 | Phosphorylation of Emi1 |
| WP:WP1403 | 0.00829062394376 | 0.136363636364 | CCNA1 CCNA2 CCNB1 | AMP-activated Protein Kinase (AMPK) Signaling |
| HP:0006498 | 0.00890156886321 | 0.136363636364 | CDT1 ORC1 GMNN | Aplasia/Hypoplasia of the patella |
| WP:WP707 | 0.00950518438845 | 0.136363636364 | CCNB1 CDK1 CCNB2 | DNA Damage Response |
| REAC:R-HSA-2980766 | 0.0101405184691 | 0.136363636364 | CCNB1 CDK1 CCNB2 | Nuclear Envelope Breakdown |
| KEGG:05166 | 0.010190740436 | 0.181818181818 | CCNA1 CCNA2 CREBBP CCNB2 | Human T-cell leukemia virus 1 infection |
| WP:WP53 | 0.0102744787089 | 0.0909090909091 | RBL1 RBL2 | ID signaling pathway |
| WP:WP1530 | 0.0108302376434 | 0.136363636364 | CCNB1 CDK1 CCNB2 | miRNA Regulation of DNA Damage Response |
| HP:0000059 | 0.0109294005379 | 0.136363636364 | CDT1 ORC1 GMNN | Hypoplastic labia majora |
| HP:0000327 | 0.0109416299951 | 0.181818181818 | CDT1 ORC1 CREBBP GMNN | Hypoplasia of the maxilla |
| HP:0003100 | 0.0120484906767 | 0.136363636364 | CDT1 ORC1 GMNN | Slender long bone |
| GO:0000075 | 0.0121509642952 | 0.272727272727 | CDT1 ORC1 RBL2 CDK1 CCNB1 TICRR | cell cycle checkpoint |
| GO:0044774 | 0.0127353855697 | 0.227272727273 | CCNB1 ORC1 RBL2 CDK1 TICRR | mitotic DNA integrity checkpoint |
| CORUM:5614 | 0.0131556336706 | 0.0909090909091 | RBL1 RBL2 | Emerin complex 32 |
| GO:0045786 | 0.0144613495035 | 0.363636363636 | CDT1 RBL1 ORC1 RBL2 CCNB1 CDK1 GMNN TICRR | negative regulation of cell cycle |
| HP:0012881 | 0.0158530787672 | 0.136363636364 | CDT1 ORC1 GMNN | Abnormality of the labia majora |
| HP:0000326 | 0.0172065444469 | 0.181818181818 | CDT1 ORC1 CREBBP GMNN | Abnormality of the maxilla |
| KEGG:05222 | 0.0182463181319 | 0.136363636364 | CKS1B CKS2 SKP2 | Small cell lung cancer |
| GO:0005654 | 0.0183985716155 | 0.727272727273 | CDT1 MCIDAS CREBBP GMNN PKMYT1 ORC1 TICRR RBL2 CCNA1 CDK1 SKP2 CCNB1 CKS1B RBL1 CCNA2 PHF8 | nucleoplasm |
| REAC:R-HSA-212436 | 0.018551985949 | 0.363636363636 | RBL1 SKP2 RBL2 CCNA1 CDK1 CREBBP CCNB1 CCNA2 | Generic Transcription Pathway |
| GO:0006260 | 0.0213681018243 | 0.272727272727 | CDT1 ORC1 CDK1 GMNN TICRR CCNA2 | DNA replication |
| GO:0003682 | 0.0217012372696 | 0.318181818182 | CDT1 CREBBP RBL1 RBL2 PHF8 GMNN TICRR | chromatin binding |
| GO:1901990 | 0.0225622230283 | 0.318181818182 | CDT1 RBL1 ORC1 RBL2 CDK1 CCNB1 TICRR | regulation of mitotic cell cycle phase transition |
| GO:0007077 | 0.022900928028 | 0.136363636364 | CCNB1 CDK1 CCNB2 | mitotic nuclear envelope disassembly |
| REAC:R-HSA-68827 | 0.0229225657581 | 0.136363636364 | CDT1 ORC1 GMNN | CDT1 association with the CDC6:ORC:origin complex |
| HP:0000413 | 0.023816759106 | 0.136363636364 | CDT1 ORC1 GMNN | Atresia of the external auditory canal |
| REAC:R-HSA-2465910 | 0.0247492288517 | 0.0909090909091 | CCNB1 CDK1 | MASTL Facilitates Mitotic Progression |
| HP:0006710 | 0.0296639635299 | 0.136363636364 | CDT1 ORC1 GMNN | Aplasia/Hypoplasia of the clavicles |
| HP:0000066 | 0.031804046258 | 0.136363636364 | CDT1 ORC1 GMNN | Labial hypoplasia |
| WP:000000 | 0.0341427164554 | 0.727272727273 | CDT1 CKS2 CREBBP GMNN PKMYT1 ORC1 CCNB2 RBL2 CCNA1 CDK1 SKP2 CCNB1 CKS1B RBL1 CCNA2 PHF8 | WIKIPATHWAYS |
| REAC:R-HSA-68867 | 0.0350345282182 | 0.136363636364 | CDT1 ORC1 GMNN | Assembly of the pre-replicative complex |
| GO:1901987 | 0.0360027489759 | 0.318181818182 | CDT1 RBL1 ORC1 RBL2 CDK1 CCNB1 TICRR | regulation of cell cycle phase transition |
| REAC:R-HSA-4419969 | 0.0362339328935 | 0.0909090909091 | CCNB1 CDK1 | Depolymerisation of the Nuclear Lamina |
| HP:0012815 | 0.0363834389622 | 0.136363636364 | CDT1 ORC1 GMNN | Hypoplastic female external genitalia |
| HP:0000189 | 0.0393442345928 | 0.181818181818 | CDT1 ORC1 CREBBP GMNN | Narrow palate |
| GO:0030397 | 0.039619012417 | 0.136363636364 | CCNB1 CDK1 CCNB2 | membrane disassembly |
| GO:0051081 | 0.039619012417 | 0.136363636364 | CCNB1 CDK1 CCNB2 | nuclear envelope disassembly |
| REAC:R-HSA-174184 | 0.0398407594538 | 0.136363636364 | CCNA1 CCNA2 CDK1 | Cdc20:Phospho-APC/C mediated degradation of Cyclin A |
| REAC:R-HSA-73857 | 0.0400365473952 | 0.363636363636 | RBL1 SKP2 RBL2 CCNA1 CDK1 CREBBP CCNB1 CCNA2 | RNA Polymerase II Transcription |
| REAC:R-HSA-179419 | 0.0415332126901 | 0.136363636364 | CCNA1 CCNA2 CDK1 | APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint |
| REAC:R-HSA-75035 | 0.0427836044327 | 0.0909090909091 | CCNB1 CDK1 | Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex |
| HP:0010311 | 0.0467978221321 | 0.136363636364 | CDT1 ORC1 GMNN | Aplasia/Hypoplasia of the breasts |
| GO:0043549 | 0.0483972475918 | 0.363636363636 | RBL1 CCNB2 RBL2 CCNA1 CDK1 PKMYT1 CCNB1 CCNA2 | regulation of kinase activity |
| REAC:R-HSA-8852276 | 0.0487698380601 | 0.136363636364 | CCNB1 CDK1 CCNB2 | The role of GTSE1 in G2/M progression after G2 checkpoint |
| REAC:R-HSA-6804116 | 0.0498695456423 | 0.0909090909091 | CCNA1 CCNA2 | TP53 Regulates Transcription of Genes Involved in G1 Cell Cycle Arrest |
| CORUM:7185 | 0.0499021917043 | 0.0454545454545 | CCNB1 | CCNB1-CCNF complex |
Edges
| Protein 1 | Protein 2 | Score | Precision | Evidence |
|---|---|---|---|---|
| CCNB1 | CDK1 | 1.0 | 0.949 | hein_WMM bioplex (CDK1) bioplex_WMM Guru hein (CCNB1,CDK1) gupta_WMM fraction boldt_WMM |
| CCNB2 | CDK1 | 1.0 | 0.949 | hein_WMM bioplex (CDK1) bioplex_WMM Guru hein (CCNB2,CDK1) gupta_WMM fraction |
| CCNA2 | CCNA1 | 1.0 | 0.949 | bioplex (CCNA2) bioplex_WMM |
| CKS2 | CDK1 | 1.0 | 0.949 | hein_WMM bioplex (CDK1,CKS2) bioplex_WMM Guru hein (CDK1) fraction |
| GMNN | CDT1 | 1.0 | 0.949 | hein_WMM bioplex (GMNN) bioplex_WMM hein (CDT1,GMNN) |
| CDK1 | CKS1B | 0.996 | 0.926 | hein_WMM bioplex (CDK1,CKS1B) bioplex_WMM Guru hein (CDK1) gupta_WMM fraction |
| CCNA2 | RBL1 | 0.989 | 0.903 | bioplex (CCNA2) bioplex_WMM boldt boldt_WMM |
| CCNA2 | PKMYT1 | 0.973 | 0.886 | hein_WMM bioplex (CCNA2) bioplex_WMM hein (CCNA2) |
| CCNA2 | CKS1B | 0.966 | 0.876 | hein_WMM bioplex (CCNA2,CKS1B) bioplex_WMM hein (CCNA2) |
| CCNA2 | SCAPER | 0.961 | 0.869 | hein_WMM bioplex (CCNA2) bioplex_WMM hein (CCNA2) |
| CKS1B | SKP2 | 0.96 | 0.865 | hein_WMM bioplex (CKS1B) bioplex_WMM youn_WMM |
| CCNA2 | SKP2 | 0.959 | 0.865 | hein_WMM bioplex (CCNA2) bioplex_WMM hein (CCNA2) |
| CCNA2 | CDK1 | 0.957 | 0.863 | hein_WMM bioplex (CCNA2,CDK1) bioplex_WMM hein (CCNA2,CDK1) gupta_WMM |
| CCNA2 | GMNN | 0.926 | 0.844 | hein_WMM bioplex (CCNA2,GMNN) bioplex_WMM boldt hein (CCNA2,GMNN) boldt_WMM |
| CCNA2 | CDT1 | 0.89 | 0.818 | hein_WMM bioplex (CCNA2) bioplex_WMM hein (CCNA2,CDT1) |
| CCNB1 | CKS1B | 0.815 | 0.773 | hein_WMM bioplex (CKS1B) bioplex_WMM youn_WMM hein (CCNB1) |
| CCNB1 | CKS2 | 0.765 | 0.749 | hein_WMM bioplex (CKS2) bioplex_WMM youn_WMM hein (CCNB1) |
| CCNA2 | CREBBP | 0.761 | 0.749 | bioplex (CCNA2) bioplex_WMM boldt boldt_WMM |
| CCNA2 | RBL2 | 0.704 | 0.725 | bioplex (CCNA2) bioplex_WMM boldt_WMM |
| CDK1 | PKMYT1 | 0.462 | 0.6 | hein_WMM bioplex (CDK1) bioplex_WMM hein (CDK1) gupta_WMM |
| CCNB2 | CKS1B | 0.403 | 0.562 | hein_WMM bioplex (CKS1B) bioplex_WMM youn_WMM gupta_WMM |
| CCNA2 | TICRR | 0.385 | 0.55 | bioplex (CCNA2) bioplex_WMM |
| PKMYT1 | CKS1B | 0.348 | 0.536 | hein_WMM bioplex (CKS1B) bioplex_WMM |
| CKS1B | CDT1 | 0.322 | 0.511 | hein_WMM bioplex (CKS1B) bioplex_WMM |
| GMNN | MCIDAS | 0.287 | 0.489 | bioplex (GMNN) bioplex_WMM boldt_WMM |
| CCNB2 | CKS2 | 0.229 | 0.468 | hein_WMM bioplex (CKS2) bioplex_WMM youn_WMM |
| CDK1 | SKP2 | 0.219 | 0.466 | hein_WMM bioplex (CDK1,SKP2) bioplex_WMM hein (CDK1) |
| GMNN | MTMR1 | 0.192 | 0.445 | bioplex (GMNN) bioplex_WMM |
| GMNN | CKS1B | 0.134 | 0.406 | hein_WMM bioplex (CKS1B,GMNN) bioplex_WMM hein (GMNN) |
| CCNA2 | CKS2 | 0.115 | 0.385 | hein_WMM bioplex (CCNA2,CKS2) bioplex_WMM |
| CCNA2 | PHF8 | 0.107 | 0.373 | bioplex (CCNA2) bioplex_WMM |
| CCNA2 | ORC1 | 0.082 | 0.35 | hein_WMM bioplex (CCNA2) bioplex_WMM hein (CCNA2) |
| CKS2 | CDT1 | 0.063 | 0.348 | bioplex (CKS2) bioplex_WMM |
| GMNN | SKP2 | 0.059 | 0.333 | hein_WMM bioplex (GMNN) bioplex_WMM hein (GMNN) |
| GMNN | CCDC146 | 0.054 | 0.304 | bioplex (CCDC146) bioplex_WMM |
| CKS2 | CKS1B | 0.053 | 0.302 | hein_WMM bioplex (CKS1B) bioplex_WMM youn_WMM |
| CCNB2 | PKMYT1 | 0.043 | 0.272 | hein_WMM bioplex_WMM hein (CCNB2) |
| CCNB1 | PKMYT1 | 0.037 | 0.268 | hein_WMM bioplex_WMM hein (CCNB1) gupta_WMM |
| CKS2 | PKMYT1 | 0.036 | 0.266 | hein_WMM bioplex (CKS2) bioplex_WMM |
| CKS1B | TRIM49 | 0.027 | 0.232 | bioplex (TRIM49) bioplex_WMM |
| CKS2 | GMNN | 0.021 | 0.185 | bioplex (CKS2,GMNN) bioplex_WMM |
| CCNB1 | CCNB2 | 0.017 | 0.174 | hein_WMM bioplex_WMM youn_WMM gupta_WMM fraction |
| RBL1 | CREBBP | 0.016 | 0.163 | bioplex_WMM boldt boldt_WMM |
| CKS2 | SKP2 | 0.015 | 0.143 | hein_WMM bioplex_WMM WMM_only |
| RBL2 | CREBBP | 0.014 | 0.137 | bioplex_WMM WMM_only boldt_WMM |
| PKMYT1 | CDT1 | 0.012 | 0.145 | hein_WMM bioplex_WMM WMM_only |
| CCNB1 | CCNA2 | 0.012 | 0.152 | hein_WMM bioplex_WMM gupta_WMM WMM_only |
| RBL2 | RBL1 | 0.011 | 0.149 | bioplex_WMM WMM_only boldt_WMM |
| CCNB2 | CCNA2 | 0.01 | 0.106 | hein_WMM bioplex_WMM WMM_only |
| CCNB1 | CDT1 | 0.01 | 0.097 | bioplex_WMM WMM_only |
| CCNB2 | CDT1 | 0.01 | 0.104 | bioplex_WMM WMM_only |
| GMNN | PKMYT1 | 0.009 | 0.115 | hein_WMM bioplex_WMM WMM_only |
| SCAPER | ORC1 | 0.009 | 0.107 | hein_WMM bioplex_WMM WMM_only |
| CDK1 | RBL2 | 0.009 | 0.105 | bioplex_WMM WMM_only |
| CCNB2 | GMNN | 0.009 | 0.102 | bioplex_WMM WMM_only |
| PKMYT1 | SKP2 | 0.009 | 0.098 | hein_WMM bioplex_WMM WMM_only |
| SCAPER | TICRR | 0.009 | 0.095 | bioplex_WMM WMM_only |
| CCNA1 | ORC1 | 0.009 | 0.095 | bioplex_WMM WMM_only |
| SCAPER | CCNA1 | 0.009 | 0.095 | bioplex_WMM WMM_only |
| CCNA1 | TICRR | 0.009 | 0.095 | bioplex_WMM WMM_only |
| TICRR | ORC1 | 0.009 | 0.095 | bioplex_WMM WMM_only |
| CCNB1 | GMNN | 0.009 | 0.095 | bioplex_WMM WMM_only |
| SCAPER | PHF8 | 0.008 | 0.092 | bioplex_WMM youn_WMM WMM_only |
| CCNA1 | PHF8 | 0.008 | 0.091 | bioplex_WMM WMM_only |
| PHF8 | TICRR | 0.008 | 0.091 | bioplex_WMM WMM_only |
| PHF8 | ORC1 | 0.008 | 0.091 | bioplex_WMM WMM_only |
| CDT1 | SCAPER | 0.008 | 0.09 | hein_WMM bioplex_WMM WMM_only |
| PKMYT1 | SCAPER | 0.008 | 0.088 | hein_WMM bioplex_WMM WMM_only |
| CKS1B | RBL1 | 0.008 | 0.088 | bioplex_WMM WMM_only |
| GMNN | SCAPER | 0.008 | 0.087 | hein_WMM bioplex_WMM WMM_only |
| CDK1 | CREBBP | 0.008 | 0.083 | bioplex_WMM WMM_only |
| CKS1B | SCAPER | 0.008 | 0.081 | hein_WMM bioplex_WMM youn_WMM WMM_only |
| CDK1 | SCAPER | 0.008 | 0.085 | hein_WMM bioplex_WMM gupta_WMM WMM_only |
| SKP2 | TRIM49 | 0.008 | 0.085 | bioplex (TRIM49) bioplex_WMM |
| RBL2 | CKS1B | 0.008 | 0.081 | bioplex_WMM WMM_only |
| RBL1 | SCAPER | 0.008 | 0.082 | bioplex_WMM WMM_only |
| RBL1 | CCNA1 | 0.008 | 0.082 | bioplex_WMM WMM_only |
| RBL1 | TICRR | 0.008 | 0.082 | bioplex_WMM WMM_only |
| RBL1 | ORC1 | 0.008 | 0.082 | bioplex_WMM WMM_only |
| SKP2 | SCAPER | 0.008 | 0.075 | hein_WMM bioplex_WMM WMM_only |
| CDT1 | MCIDAS | 0.008 | 0.067 | bioplex_WMM WMM_only |
| RBL2 | SCAPER | 0.008 | 0.067 | bioplex_WMM WMM_only |
| RBL2 | ORC1 | 0.008 | 0.067 | bioplex_WMM WMM_only |
| RBL2 | TICRR | 0.008 | 0.067 | bioplex_WMM WMM_only |
| CDT1 | CCNA1 | 0.008 | 0.067 | bioplex_WMM WMM_only |
| RBL2 | CCNA1 | 0.008 | 0.067 | bioplex_WMM WMM_only |
| CDT1 | TICRR | 0.008 | 0.067 | bioplex_WMM WMM_only |
| CKS1B | CREBBP | 0.008 | 0.067 | bioplex_WMM WMM_only |
| CKS2 | RBL1 | 0.008 | 0.067 | bioplex_WMM WMM_only |
| SKP2 | RBL1 | 0.008 | 0.071 | bioplex_WMM WMM_only |
| PKMYT1 | CCNA1 | 0.008 | 0.066 | bioplex_WMM WMM_only |
| SCAPER | CREBBP | 0.008 | 0.066 | bioplex_WMM WMM_only |
| PKMYT1 | TICRR | 0.008 | 0.066 | bioplex_WMM WMM_only |
| CCNA1 | CREBBP | 0.008 | 0.066 | bioplex_WMM WMM_only |
| TICRR | CREBBP | 0.008 | 0.066 | bioplex_WMM WMM_only |
| CREBBP | ORC1 | 0.008 | 0.066 | bioplex_WMM WMM_only |
| CDT1 | ORC1 | 0.008 | 0.061 | hein_WMM bioplex_WMM WMM_only |
| PKMYT1 | ORC1 | 0.008 | 0.059 | hein_WMM bioplex_WMM WMM_only |
| CKS2 | RBL2 | 0.008 | 0.053 | bioplex_WMM WMM_only |
| PHF8 | CREBBP | 0.008 | 0.052 | bioplex_WMM youn_WMM WMM_only |
| CDK1 | TICRR | 0.008 | 0.05 | bioplex_WMM WMM_only |
| CDK1 | CCNA1 | 0.008 | 0.05 | bioplex_WMM WMM_only |
| RBL2 | SKP2 | 0.008 | 0.047 | bioplex_WMM WMM_only |
| RBL1 | PHF8 | 0.008 | 0.046 | bioplex_WMM WMM_only |
| CKS1B | MCIDAS | 0.008 | 0.046 | bioplex_WMM WMM_only |
| CKS1B | TICRR | 0.008 | 0.046 | bioplex_WMM WMM_only |
| CKS1B | CCNA1 | 0.008 | 0.046 | bioplex_WMM WMM_only |
| GMNN | ORC1 | 0.008 | 0.042 | hein_WMM bioplex_WMM WMM_only |
| CDT1 | PHF8 | 0.008 | 0.04 | bioplex_WMM WMM_only |
| RBL2 | PHF8 | 0.008 | 0.04 | bioplex_WMM WMM_only |
| CKS1B | ORC1 | 0.008 | 0.034 | hein_WMM bioplex_WMM WMM_only |
| CDK1 | ORC1 | 0.008 | 0.032 | hein_WMM bioplex_WMM fraction |
| SKP2 | CCNA1 | 0.008 | 0.031 | bioplex_WMM WMM_only |
| SKP2 | MCIDAS | 0.008 | 0.031 | bioplex_WMM WMM_only |
| SKP2 | TICRR | 0.008 | 0.031 | bioplex_WMM WMM_only |
| CKS2 | TICRR | 0.008 | 0.033 | bioplex_WMM WMM_only |
| CKS2 | MCIDAS | 0.008 | 0.033 | bioplex_WMM WMM_only |
| CKS2 | SCAPER | 0.008 | 0.033 | bioplex_WMM WMM_only |
| CKS2 | CCNA1 | 0.008 | 0.033 | bioplex_WMM WMM_only |
| CKS2 | ORC1 | 0.008 | 0.033 | bioplex_WMM WMM_only |
| CKS2 | CREBBP | 0.008 | 0.036 | bioplex_WMM WMM_only |
| GMNN | RBL1 | 0.008 | 0.04 | bioplex_WMM WMM_only |
| SKP2 | CREBBP | 0.008 | 0.037 | bioplex_WMM WMM_only |
| PKMYT1 | PHF8 | 0.008 | 0.034 | bioplex_WMM WMM_only |
| CCNA2 | MCIDAS | 0.008 | 0.033 | bioplex_WMM WMM_only |
| CDK1 | PHF8 | 0.008 | 0.033 | bioplex_WMM WMM_only |
| MCIDAS | MTMR1 | 0.008 | 0.026 | bioplex_WMM WMM_only |
| GMNN | TICRR | 0.008 | 0.025 | bioplex_WMM WMM_only |
| GMNN | CCNA1 | 0.008 | 0.025 | bioplex_WMM WMM_only |
| CKS1B | PHF8 | 0.008 | 0.024 | bioplex_WMM youn_WMM WMM_only |
| SKP2 | ORC1 | 0.008 | 0.026 | hein_WMM bioplex_WMM WMM_only |
| GMNN | RBL2 | 0.008 | 0.023 | bioplex_WMM WMM_only |
| CCNB2 | RBL1 | 0.008 | 0.014 | bioplex_WMM WMM_only |
| CKS2 | PHF8 | 0.008 | 0.013 | bioplex_WMM youn_WMM WMM_only |
| SKP2 | PHF8 | 0.008 | 0.01 | bioplex_WMM youn_WMM WMM_only |
| CCNB2 | RBL2 | 0.007 | 0.005 | bioplex_WMM WMM_only |
| GMNN | CREBBP | 0.007 | 0.013 | bioplex_WMM WMM_only |
| RBL1 | CDT1 | 0.007 | 0.01 | bioplex_WMM WMM_only |
| CCNB2 | CREBBP | 0.007 | 0.01 | bioplex_WMM WMM_only |
| PKMYT1 | RBL1 | 0.007 | 0.005 | bioplex_WMM WMM_only |
| RBL2 | CDT1 | 0.007 | 0.012 | bioplex_WMM WMM_only |
| CDK1 | RBL1 | 0.007 | 0.01 | bioplex_WMM gupta_WMM WMM_only |
| GMNN | PHF8 | 0.007 | 0.005 | bioplex_WMM WMM_only |
| CCNB1 | RBL1 | 0.007 | 0.002 | bioplex_WMM WMM_only |
| PKMYT1 | RBL2 | 0.007 | 0.003 | bioplex_WMM WMM_only |
| CDT1 | CREBBP | 0.007 | 0.003 | bioplex_WMM WMM_only |
| CCNB1 | RBL2 | 0.007 | 0.007 | bioplex_WMM WMM_only |
| PKMYT1 | CREBBP | 0.007 | 0.008 | bioplex_WMM WMM_only |
| CCNB1 | SCAPER | 0.007 | 0.003 | youn_WMM gupta_WMM WMM_only |
| CDT1 | MTMR1 | 0.007 | 0.006 | bioplex_WMM WMM_only |
| CDK1 | MTMR1 | 0.007 | 0.004 | bioplex_WMM gupta_WMM WMM_only |
| CCNB1 | MTMR1 | 0.007 | 0.001 | youn_WMM gupta_WMM WMM_only |
| CKS1B | MTMR1 | 0.007 | 0.002 | bioplex_WMM youn_WMM WMM_only |
| CCNB2 | PHF8 | 0.007 | 0.003 | youn_WMM WMM_only |
| PKMYT1 | MTMR1 | 0.007 | 0.003 | gupta_WMM WMM_only |
| CCNB2 | MTMR1 | 0.007 | 0.003 | gupta_WMM WMM_only |
| SCAPER | MTMR1 | 0.007 | 0.001 | youn_WMM WMM_only |
| CCNB2 | SCAPER | 0.007 | 0.001 | gupta_WMM WMM_only |
| CCNB1 | PHF8 | 0.007 | 0.004 | youn_WMM WMM_only |
| MTMR1 | PHF8 | 0.007 | 0.001 | youn_WMM WMM_only |
| CCNA2 | MTMR1 | 0.007 | 0.004 | bioplex_WMM gupta_WMM WMM_only |
| CDK1 | MCIDAS | 0.007 | 0.005 | bioplex_WMM WMM_only |
| CKS2 | MTMR1 | 0.007 | 0.002 | bioplex_WMM youn_WMM WMM_only |
| SKP2 | MTMR1 | 0.007 | 0.003 | bioplex_WMM WMM_only |
| SKP2 | CDT1 | 0.005 | 0.008 | hein_WMM bioplex_WMM hein (CDT1) |
| CDK1 | CDT1 | 0.005 | 0.006 | hein_WMM bioplex (CDK1) bioplex_WMM |
| CCNB1 | CREBBP | 0.003 | 0.011 | bioplex_WMM fraction |
| CCNB2 | SKP2 | 0.003 | 0.007 | hein_WMM bioplex_WMM fraction |
| CDK1 | GMNN | 0.0 | 0.012 | hein_WMM bioplex (CDK1,GMNN) bioplex_WMM |
| CCNB1 | SKP2 | 0.0 | 0.012 | hein_WMM bioplex_WMM fraction |
Images
Click to enlarge
Complex HuMAP2_02530 has an average edge precision of 0.187 which is ranked 6348 out of all 6965 complexes.
Related Complexes
| Genename | Complexes |
|---|---|
| CDK1 | HuMAP2_01003 HuMAP2_01010 HuMAP2_02530 |
| CKS1B | HuMAP2_01003 HuMAP2_01010 HuMAP2_02530 |
| SCAPER | HuMAP2_02530 |
| MCIDAS | HuMAP2_02530 HuMAP2_02598 |
| CCNA2 | HuMAP2_01003 HuMAP2_02530 HuMAP2_06689 |
| PHF8 | HuMAP2_02530 |
| ORC1 | HuMAP2_02530 |
| TRIM49 | HuMAP2_02530 |
| CCDC146 | HuMAP2_02530 HuMAP2_02598 |
| CCNB1 | HuMAP2_00550 HuMAP2_01003 HuMAP2_01010 HuMAP2_02530 HuMAP2_05166 |
| PKMYT1 | HuMAP2_01003 HuMAP2_02530 |
| SKP2 | HuMAP2_01003 HuMAP2_02530 HuMAP2_04602 |
| TICRR | HuMAP2_02530 |
| RBL2 | HuMAP2_01003 HuMAP2_02530 HuMAP2_06056 |
| CREBBP | HuMAP2_02530 HuMAP2_02545 |
| CKS2 | HuMAP2_01003 HuMAP2_01010 HuMAP2_02530 |
| CDT1 | HuMAP2_01003 HuMAP2_02530 HuMAP2_03813 |
| CCNA1 | HuMAP2_02530 |
| CCNB2 | HuMAP2_00557 HuMAP2_01003 HuMAP2_01010 HuMAP2_02530 HuMAP2_04188 |
| MTMR1 | HuMAP2_02530 HuMAP2_02598 |
| GMNN | HuMAP2_01003 HuMAP2_02530 HuMAP2_02598 HuMAP2_03813 |
| RBL1 | HuMAP2_01003 HuMAP2_02530 HuMAP2_04287 HuMAP2_06056 |