hu.MAP 2.0: Complex View
Human Protein Complex Map
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Complex: HuMAP2_02537
Confidence: Medium
Proteins| Genename | Protein Name | Links |
|---|---|---|
| IMP3 | U3 small nucleolar ribonucleoprotein protein IMP3 (U3 snoRNP protein IMP3) (BRMS2) | UniProt NCBI |
| MPHOSPH10 | U3 small nucleolar ribonucleoprotein protein MPP10 (M phase phosphoprotein 10) | UniProt NCBI |
| IMP4 | U3 small nucleolar ribonucleoprotein protein IMP4 (U3 snoRNP protein IMP4) (Brix domain-containing protein 4) | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| CORUM:533 | 2.25356268047e-10 | 1.0 | IMP4 MPHOSPH10 IMP3 | IMP3-IMP4-MPP10 complex |
| GO:0034457 | 9.08185760231e-08 | 1.0 | IMP4 MPHOSPH10 IMP3 | Mpp10 complex |
| KEGG:03008 | 2.19979431659e-06 | 1.0 | IMP4 MPHOSPH10 IMP3 | Ribosome biogenesis in eukaryotes |
| REAC:R-HSA-6790901 | 1.53852062946e-05 | 1.0 | IMP4 MPHOSPH10 IMP3 | rRNA modification in the nucleus and cytosol |
| GO:0030686 | 0.000331851076788 | 1.0 | IMP4 MPHOSPH10 IMP3 | 90S preribosome |
| REAC:R-HSA-6791226 | 0.00043699470959 | 1.0 | IMP4 MPHOSPH10 IMP3 | Major pathway of rRNA processing in the nucleolus and cytosol |
| REAC:R-HSA-8868773 | 0.000513949964862 | 1.0 | IMP4 MPHOSPH10 IMP3 | rRNA processing in the nucleus and cytosol |
| REAC:R-HSA-72312 | 0.000599447561444 | 1.0 | IMP4 MPHOSPH10 IMP3 | rRNA processing |
| GO:0032040 | 0.000648444632805 | 1.0 | IMP4 MPHOSPH10 IMP3 | small-subunit processome |
| GO:0030684 | 0.00564855215433 | 1.0 | IMP4 MPHOSPH10 IMP3 | preribosome |
| REAC:R-HSA-8953854 | 0.0206735000409 | 1.0 | IMP4 MPHOSPH10 IMP3 | Metabolism of RNA |
Edges
| Protein 1 | Protein 2 | Score | Precision | Evidence |
|---|---|---|---|---|
| MPHOSPH10 | IMP3 | 0.232 | 0.47 | bioplex_WMM Guru youn_WMM fraction |
| IMP4 | MPHOSPH10 | 0.068 | 0.349 | bioplex_WMM Guru youn_WMM fraction treiber_WMM |
| IMP4 | IMP3 | 0.028 | 0.233 | bioplex_WMM youn_WMM WMM_only treiber_WMM |
Images
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Complex HuMAP2_02537 has an average edge precision of 0.351 which is ranked 3944 out of all 6965 complexes.
Related Complexes
| Genename | Complexes |
|---|---|
| IMP3 | HuMAP2_02537 HuMAP2_06590 HuMAP2_06780 |
| MPHOSPH10 | HuMAP2_02537 HuMAP2_06590 HuMAP2_06780 |
| IMP4 | HuMAP2_02537 HuMAP2_06590 HuMAP2_06780 |