hu.MAP 2.0: Complex View
Human Protein Complex Map
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Complex: HuMAP2_02541
Confidence: Medium
Proteins| Genename | Protein Name | Links |
|---|---|---|
| SLC1A5 | Neutral amino acid transporter B(0) (ATB(0)) (Baboon M7 virus receptor) (RD114/simian type D retrovirus receptor) (Sodium-dependent neutral amino acid transporter type 2) (Solute carrier family 1 member 5) | UniProt NCBI |
| SLC35F6 | Solute carrier family 35 member F6 (ANT2-binding protein) (ANT2BP) (Transport and Golgi organization 9 homolog) | UniProt NCBI |
| ESYT2 | Extended synaptotagmin-2 (E-Syt2) (Chr2Syt) | UniProt NCBI |
| PTDSS1 | Phosphatidylserine synthase 1 (PSS-1) (PtdSer synthase 1) (EC 2.7.8.29) (Serine-exchange enzyme I) | UniProt NCBI |
| STT3A | Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit STT3A (Oligosaccharyl transferase subunit STT3A) (STT3-A) (EC 2.4.99.18) (B5) (Integral membrane protein 1) (Transmembrane protein TMC) | UniProt NCBI |
| ABCD3 | ATP-binding cassette sub-family D member 3 (70 kDa peroxisomal membrane protein) (PMP70) | UniProt NCBI |
| SLC35E1 | Solute carrier family 35 member E1 | UniProt NCBI |
| DHCR7 | 7-dehydrocholesterol reductase (7-DHC reductase) (EC 1.3.1.21) (Putative sterol reductase SR-2) (Sterol Delta(7)-reductase) | UniProt NCBI |
| TMEM33 | Transmembrane protein 33 (Protein DB83) (SHINC-3) | UniProt NCBI |
| ABCB7 | ATP-binding cassette sub-family B member 7, mitochondrial (ATP-binding cassette transporter 7) (ABC transporter 7 protein) | UniProt NCBI |
| ATP2A2 | Sarcoplasmic/endoplasmic reticulum calcium ATPase 2 (SERCA2) (SR Ca(2+)-ATPase 2) (EC 7.2.2.10) (Calcium pump 2) (Calcium-transporting ATPase sarcoplasmic reticulum type, slow twitch skeletal muscle isoform) (Endoplasmic reticulum class 1/2 Ca(2+) ATPase) | UniProt NCBI |
| COX15 | Cytochrome c oxidase assembly protein COX15 homolog | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| MIRNA:hsa-miR-3664-5p | 0.00306555202276 | 0.333333333333 | SLC1A5 ESYT2 SLC35E1 TMEM33 | hsa-miR-3664-5p |
| MIRNA:hsa-miR-4284 | 0.0165391169292 | 0.416666666667 | ESYT2 SLC1A5 TMEM33 SLC35E1 SLC35F6 | hsa-miR-4284 |
| GO:0031090 | 0.0185226245312 | 0.833333333333 | TMEM33 STT3A PTDSS1 SLC35F6 DHCR7 COX15 ABCB7 ESYT2 ATP2A2 ABCD3 | organelle membrane |
| KEGG:02010 | 0.0228761648372 | 0.166666666667 | ABCB7 ABCD3 | ABC transporters |
| HP:0000171 | 0.036657717165 | 0.166666666667 | PTDSS1 DHCR7 | Microglossia |
| CORUM:6507 | 0.0499809905632 | 0.0833333333333 | ATP2A2 | SERCA-PLN complex |
| CORUM:6516 | 0.0499809905632 | 0.0833333333333 | ATP2A2 | SLN-PLN-SERCA2A complex |
Edges
| Protein 1 | Protein 2 | Score | Precision | Evidence |
|---|---|---|---|---|
| SLC1A5 | ATP2A2 | 0.146 | 0.408 | hein_WMM bioplex (SLC1A5) bioplex_WMM boldt hein (ATP2A2) gupta_WMM boldt_WMM |
| ESYT2 | ATP2A2 | 0.085 | 0.35 | hein_WMM bioplex_WMM boldt hein (ATP2A2) gupta_WMM boldt_WMM |
| ESYT2 | COX15 | 0.073 | 0.357 | bioplex_WMM boldt youn_WMM gupta_WMM fraction boldt_WMM |
| ATP2A2 | TMEM33 | 0.064 | 0.348 | hein_WMM bioplex_WMM boldt hein (ATP2A2) gupta_WMM boldt_WMM |
| PTDSS1 | ATP2A2 | 0.059 | 0.333 | hein_WMM bioplex_WMM boldt hein (ATP2A2) gupta_WMM boldt_WMM |
| ATP2A2 | ABCD3 | 0.048 | 0.294 | hein_WMM bioplex_WMM boldt hein (ATP2A2) gupta_WMM boldt_WMM treiber_WMM |
| STT3A | ATP2A2 | 0.039 | 0.264 | hein_WMM bioplex_WMM boldt hein (ATP2A2) gupta_WMM boldt_WMM |
| SLC35E1 | ATP2A2 | 0.037 | 0.264 | hein_WMM bioplex_WMM boldt hein (ATP2A2) gupta_WMM boldt_WMM |
| DHCR7 | ATP2A2 | 0.033 | 0.247 | hein_WMM bioplex_WMM boldt hein (ATP2A2) gupta_WMM boldt_WMM |
| SLC35F6 | ATP2A2 | 0.026 | 0.224 | hein_WMM bioplex_WMM boldt hein (ATP2A2) boldt_WMM |
| ABCB7 | ATP2A2 | 0.026 | 0.219 | bioplex_WMM boldt gupta_WMM fraction boldt_WMM |
| ESYT2 | SLC1A5 | 0.013 | 0.149 | hein_WMM bioplex (SLC1A5) bioplex_WMM boldt gupta_WMM boldt_WMM |
| STT3A | SLC1A5 | 0.013 | 0.151 | hein_WMM bioplex (SLC1A5) bioplex_WMM boldt gupta_WMM boldt_WMM |
| DHCR7 | SLC1A5 | 0.009 | 0.104 | hein_WMM bioplex (SLC1A5) bioplex_WMM boldt gupta_WMM boldt_WMM |
| DHCR7 | ESYT2 | 0.009 | 0.104 | hein_WMM bioplex_WMM boldt youn_WMM gupta_WMM boldt_WMM |
| ABCB7 | SLC35F6 | 0.009 | 0.097 | hein_WMM bioplex_WMM boldt youn_WMM boldt_WMM |
| COX15 | SLC35F6 | 0.008 | 0.062 | bioplex_WMM boldt youn_WMM boldt_WMM |
| DHCR7 | PTDSS1 | 0.008 | 0.039 | hein_WMM bioplex_WMM boldt youn_WMM gupta_WMM boldt_WMM |
| DHCR7 | SLC35F6 | 0.008 | 0.031 | hein_WMM bioplex_WMM boldt youn_WMM boldt_WMM |
| SLC35E1 | SLC35F6 | 0.008 | 0.013 | hein_WMM bioplex_WMM boldt boldt_WMM |
| SLC35F6 | TMEM33 | 0.007 | 0.012 | hein_WMM bioplex_WMM boldt youn_WMM boldt_WMM |
| STT3A | SLC35F6 | 0.007 | 0.008 | hein_WMM bioplex_WMM boldt youn_WMM boldt_WMM |
| ESYT2 | SLC35F6 | 0.007 | 0.005 | hein_WMM bioplex_WMM boldt youn_WMM boldt_WMM |
| COX15 | TMEM33 | 0.007 | 0.003 | bioplex_WMM boldt youn_WMM gupta_WMM boldt_WMM |
| PTDSS1 | SLC35F6 | 0.007 | 0.003 | hein_WMM bioplex_WMM boldt youn_WMM boldt_WMM |
| COX15 | SLC1A5 | 0.007 | 0.004 | bioplex (SLC1A5) bioplex_WMM boldt gupta_WMM boldt_WMM |
| ESYT2 | TMEM33 | 0.006 | 0.003 | hein_WMM bioplex_WMM boldt youn_WMM gupta_WMM boldt_WMM |
| SLC1A5 | TMEM33 | 0.006 | 0.007 | hein_WMM bioplex (SLC1A5) bioplex_WMM boldt gupta_WMM boldt_WMM |
| SLC35F6 | SLC1A5 | 0.006 | 0.005 | hein_WMM bioplex_WMM boldt boldt_WMM |
| SLC35E1 | SLC1A5 | 0.006 | 0.003 | hein_WMM bioplex (SLC1A5) bioplex_WMM boldt gupta_WMM boldt_WMM |
| SLC35F6 | ABCD3 | 0.006 | 0.007 | hein_WMM bioplex_WMM boldt youn_WMM boldt_WMM |
| SLC1A5 | ABCD3 | 0.006 | 0.008 | hein_WMM bioplex (SLC1A5) bioplex_WMM boldt gupta_WMM boldt_WMM treiber_WMM |
| DHCR7 | STT3A | 0.006 | 0.003 | hein_WMM bioplex_WMM boldt youn_WMM gupta_WMM boldt_WMM treiber_WMM |
| PTDSS1 | SLC1A5 | 0.006 | 0.005 | hein_WMM bioplex (SLC1A5) bioplex_WMM boldt gupta_WMM boldt_WMM |
| STT3A | TMEM33 | 0.006 | 0.01 | hein_WMM bioplex_WMM boldt youn_WMM gupta_WMM boldt_WMM |
| SLC35E1 | TMEM33 | 0.006 | 0.008 | hein_WMM bioplex_WMM boldt gupta_WMM boldt_WMM |
| STT3A | ABCD3 | 0.006 | 0.009 | hein_WMM bioplex_WMM boldt youn_WMM gupta_WMM boldt_WMM |
| PTDSS1 | TMEM33 | 0.006 | 0.004 | hein_WMM bioplex_WMM boldt youn_WMM gupta_WMM boldt_WMM |
| ABCB7 | TMEM33 | 0.005 | 0.012 | bioplex_WMM boldt youn_WMM gupta_WMM boldt_WMM |
| STT3A | ESYT2 | 0.005 | 0.005 | hein_WMM bioplex_WMM boldt youn_WMM gupta_WMM boldt_WMM |
| DHCR7 | TMEM33 | 0.005 | 0.013 | hein_WMM bioplex_WMM boldt youn_WMM gupta_WMM boldt_WMM |
| DHCR7 | ABCB7 | 0.005 | 0.009 | bioplex_WMM boldt youn_WMM gupta_WMM boldt_WMM |
| TMEM33 | ABCD3 | 0.005 | 0.013 | hein_WMM bioplex_WMM boldt youn_WMM gupta_WMM boldt_WMM |
| ABCB7 | SLC35E1 | 0.005 | 0.008 | hein_WMM bioplex_WMM boldt boldt_WMM |
| DHCR7 | SLC35E1 | 0.005 | 0.011 | hein_WMM bioplex_WMM boldt gupta_WMM boldt_WMM |
| DHCR7 | ABCD3 | 0.004 | 0.009 | hein_WMM bioplex_WMM boldt youn_WMM gupta_WMM boldt_WMM |
| COX15 | ATP2A2 | 0.004 | 0.013 | bioplex_WMM boldt gupta_WMM boldt_WMM |
| ESYT2 | ABCB7 | 0.004 | 0.005 | hein_WMM bioplex_WMM boldt youn_WMM gupta_WMM boldt_WMM |
| COX15 | SLC35E1 | 0.004 | 0.007 | bioplex_WMM boldt boldt_WMM |
| DHCR7 | COX15 | 0.004 | 0.011 | bioplex_WMM boldt youn_WMM gupta_WMM boldt_WMM |
| ESYT2 | SLC35E1 | 0.004 | 0.013 | hein_WMM bioplex_WMM boldt gupta_WMM boldt_WMM |
| STT3A | COX15 | 0.004 | 0.008 | bioplex_WMM boldt youn_WMM gupta_WMM boldt_WMM |
| ABCB7 | ABCD3 | 0.004 | 0.008 | bioplex_WMM boldt youn_WMM gupta_WMM boldt_WMM |
| STT3A | PTDSS1 | 0.004 | 0.015 | hein_WMM bioplex_WMM boldt youn_WMM gupta_WMM boldt_WMM |
| ESYT2 | PTDSS1 | 0.003 | 0.018 | hein_WMM bioplex_WMM boldt youn_WMM gupta_WMM boldt_WMM |
| STT3A | ABCB7 | 0.003 | 0.017 | bioplex_WMM boldt youn_WMM gupta_WMM boldt_WMM |
| PTDSS1 | ABCD3 | 0.003 | 0.013 | hein_WMM bioplex_WMM boldt youn_WMM gupta_WMM boldt_WMM |
| STT3A | SLC35E1 | 0.003 | 0.011 | hein_WMM bioplex_WMM boldt gupta_WMM boldt_WMM |
| ESYT2 | ABCD3 | 0.003 | 0.014 | hein_WMM bioplex_WMM boldt youn_WMM gupta_WMM boldt_WMM |
| SLC35E1 | ABCD3 | 0.003 | 0.013 | hein_WMM bioplex_WMM boldt gupta_WMM boldt_WMM |
| COX15 | ABCB7 | 0.003 | 0.011 | bioplex_WMM boldt youn_WMM boldt_WMM |
| COX15 | ABCD3 | 0.003 | 0.006 | bioplex_WMM boldt youn_WMM gupta_WMM boldt_WMM |
| ABCB7 | SLC1A5 | 0.003 | 0.01 | hein_WMM bioplex (SLC1A5) bioplex_WMM boldt gupta_WMM boldt_WMM |
| ABCB7 | PTDSS1 | 0.0 | 0.014 | bioplex_WMM boldt youn_WMM boldt_WMM |
| COX15 | PTDSS1 | 0.0 | 0.01 | bioplex_WMM boldt youn_WMM gupta_WMM boldt_WMM |
| PTDSS1 | SLC35E1 | 0.0 | 0.008 | hein_WMM bioplex_WMM boldt gupta_WMM boldt_WMM |
Images
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Complex HuMAP2_02541 has an average edge precision of 0.068 which is ranked 6971 out of all 6965 complexes.
Related Complexes
| Genename | Complexes |
|---|---|
| SLC1A5 | HuMAP2_02393 HuMAP2_02541 HuMAP2_05501 |
| SLC35F6 | HuMAP2_02393 HuMAP2_02541 |
| ESYT2 | HuMAP2_00803 HuMAP2_02541 HuMAP2_05501 |
| PTDSS1 | HuMAP2_02201 HuMAP2_02541 HuMAP2_05501 |
| STT3A | HuMAP2_00485 HuMAP2_01092 HuMAP2_02541 HuMAP2_05631 HuMAP2_06974 |
| ABCD3 | HuMAP2_02541 HuMAP2_03628 HuMAP2_05501 |
| SLC35E1 | HuMAP2_02393 HuMAP2_02541 |
| DHCR7 | HuMAP2_00382 HuMAP2_02541 |
| TMEM33 | HuMAP2_02541 HuMAP2_03387 |
| ABCB7 | HuMAP2_02063 HuMAP2_02541 |
| ATP2A2 | HuMAP2_02393 HuMAP2_02541 HuMAP2_04352 HuMAP2_05501 |
| COX15 | HuMAP2_00803 HuMAP2_02541 |