hu.MAP 2.0: Complex View
Human Protein Complex Map
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Complex: HuMAP2_02551
Confidence: Medium High
Proteins| Genename | Protein Name | Links |
|---|---|---|
| RACGAP1 | Rac GTPase-activating protein 1 (Male germ cell RacGap) (MgcRacGAP) (Protein CYK4 homolog) (CYK4) (HsCYK-4) | UniProt NCBI |
| LRWD1 | Leucine-rich repeat and WD repeat-containing protein 1 (Centromere protein 33) (CENP-33) (Origin recognition complex-associated protein) (ORC-associated protein) (ORCA) | UniProt NCBI |
| SMNDC1 | Survival of motor neuron-related-splicing factor 30 (30 kDa splicing factor SMNrp) (SMN-related protein) (Survival motor neuron domain-containing protein 1) | UniProt NCBI |
| KIF23 | Kinesin-like protein KIF23 (Kinesin-like protein 5) (Mitotic kinesin-like protein 1) | UniProt NCBI |
| SHCBP1 | SHC SH2 domain-binding protein 1 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| CORUM:7440 | 6.70868171695e-06 | 0.4 | RACGAP1 KIF23 | KIF23-RACGAP1 complex |
| CORUM:929 | 1.04649653412e-05 | 0.6 | RACGAP1 SHCBP1 KIF23 | CEN complex |
| CORUM:7439 | 2.0123342217e-05 | 0.4 | RACGAP1 KIF23 | ECT2-KIF23-RACGAP1 complex |
| GO:0097149 | 0.0135228859698 | 0.4 | RACGAP1 KIF23 | centralspindlin complex |
| REAC:R-HSA-983189 | 0.0213836497757 | 0.4 | RACGAP1 KIF23 | Kinesins |
| MIRNA:hsa-miR-581 | 0.0308167272302 | 0.4 | SMNDC1 KIF23 | hsa-miR-581 |
Edges
| Protein 1 | Protein 2 | Score | Precision | Evidence |
|---|---|---|---|---|
| RACGAP1 | KIF23 | 1.0 | 0.949 | hein_WMM bioplex (RACGAP1) bioplex_WMM Guru youn_WMM hein (KIF23,RACGAP1) Malo gupta_WMM fraction boldt_WMM treiber_WMM |
| SHCBP1 | RACGAP1 | 0.957 | 0.863 | hein_WMM bioplex (RACGAP1) bioplex_WMM youn_WMM hein (RACGAP1,SHCBP1) boldt_WMM |
| KIF23 | SMNDC1 | 0.11 | 0.379 | youn_WMM gupta_WMM fraction |
| KIF23 | LRWD1 | 0.075 | 0.357 | youn_WMM gupta_WMM fraction |
| SHCBP1 | KIF23 | 0.061 | 0.334 | hein_WMM bioplex_WMM youn_WMM hein (KIF23,SHCBP1) gupta_WMM boldt_WMM |
| RACGAP1 | SMNDC1 | 0.042 | 0.27 | hein_WMM youn_WMM gupta_WMM fraction |
| SHCBP1 | LRWD1 | 0.007 | 0.001 | youn_WMM WMM_only |
| RACGAP1 | LRWD1 | 0.003 | 0.014 | youn_WMM gupta_WMM fraction |
| LRWD1 | SMNDC1 | 0.0 | 0.015 | bioplex_WMM youn_WMM gupta_WMM fraction |
Images
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Complex HuMAP2_02551 has an average edge precision of 0.354 which is ranked 3878 out of all 6965 complexes.
Related Complexes