hu.MAP 2.0: Complex View
Human Protein Complex Map
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Complex: HuMAP2_02559
Confidence: Medium
Proteins| Genename | Protein Name | Links |
|---|---|---|
| NOB1 | RNA-binding protein NOB1 (Phosphorylation regulatory protein HP-10) (Protein ART-4) | UniProt NCBI |
| UTP14A | U3 small nucleolar RNA-associated protein 14 homolog A (Antigen NY-CO-16) (Serologically defined colon cancer antigen 16) | UniProt NCBI |
| UTP14C | U3 small nucleolar RNA-associated protein 14 homolog C | UniProt NCBI |
| PNO1 | RNA-binding protein PNO1 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| REAC:R-HSA-6791226 | 3.92257636671e-06 | 1.0 | UTP14C PNO1 UTP14A NOB1 | Major pathway of rRNA processing in the nucleolus and cytosol |
| REAC:R-HSA-8868773 | 4.87252320159e-06 | 1.0 | UTP14C PNO1 UTP14A NOB1 | rRNA processing in the nucleus and cytosol |
| REAC:R-HSA-72312 | 5.98537842586e-06 | 1.0 | UTP14C PNO1 UTP14A NOB1 | rRNA processing |
| KEGG:03008 | 1.96107212107e-05 | 0.75 | UTP14C UTP14A NOB1 | Ribosome biogenesis in eukaryotes |
| REAC:R-HSA-6790901 | 4.60801423694e-05 | 0.75 | UTP14C UTP14A PNO1 | rRNA modification in the nucleus and cytosol |
| REAC:R-HSA-8953854 | 0.000676603019954 | 1.0 | UTP14C PNO1 UTP14A NOB1 | Metabolism of RNA |
| GO:0030684 | 0.0225145500348 | 0.75 | UTP14C UTP14A NOB1 | preribosome |
Edges
| Protein 1 | Protein 2 | Score | Precision | Evidence |
|---|---|---|---|---|
| UTP14C | PNO1 | 0.296 | 0.496 | bioplex (PNO1) bioplex_WMM youn_WMM |
| NOB1 | PNO1 | 0.059 | 0.328 | hein_WMM bioplex (NOB1,PNO1) bioplex_WMM youn_WMM gupta_WMM fraction |
| UTP14A | PNO1 | 0.04 | 0.267 | bioplex (PNO1) bioplex_WMM youn_WMM gupta_WMM |
| NOB1 | UTP14C | 0.008 | 0.089 | bioplex_WMM WMM_only |
| UTP14A | UTP14C | 0.008 | 0.084 | bioplex_WMM youn_WMM WMM_only |
| UTP14A | NOB1 | 0.007 | 0.005 | bioplex_WMM WMM_only |
Images
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Complex HuMAP2_02559 has an average edge precision of 0.212 which is ranked 5998 out of all 6965 complexes.
Related Complexes
| Genename | Complexes |
|---|---|
| NOB1 | HuMAP2_02559 HuMAP2_03347 HuMAP2_03680 HuMAP2_05710 HuMAP2_06629 HuMAP2_06766 |
| UTP14A | HuMAP2_00420 HuMAP2_02559 HuMAP2_06704 |
| UTP14C | HuMAP2_02559 HuMAP2_03347 HuMAP2_06766 |
| PNO1 | HuMAP2_02559 HuMAP2_03347 HuMAP2_05710 HuMAP2_06766 |