hu.MAP 2.0: Complex View
Human Protein Complex Map
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Complex: HuMAP2_02582
Confidence: High
Proteins| Genename | Protein Name | Links |
|---|---|---|
| ALDH4A1 | Delta-1-pyrroline-5-carboxylate dehydrogenase, mitochondrial (P5C dehydrogenase) (EC 1.2.1.88) (Aldehyde dehydrogenase family 4 member A1) (L-glutamate gamma-semialdehyde dehydrogenase) | UniProt NCBI |
| FH | Fumarate hydratase, mitochondrial (Fumarase) (HsFH) (EC 4.2.1.2) | UniProt NCBI |
| PGM1 | Phosphoglucomutase-1 (PGM 1) (EC 5.4.2.2) (Glucose phosphomutase 1) | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| WP:WP4595 | 0.000201260405501 | 0.666666666667 | FH ALDH4A1 | Urea cycle and associated pathways |
| KEGG:01100 | 0.0105851300972 | 1.0 | FH ALDH4A1 PGM1 | Metabolic pathways |
| REAC:R-HSA-5609974 | 0.0498572752401 | 0.333333333333 | PGM1 | Defective PGM1 causes PGM1-CDG (CDG1t) |
| WP:WP4236 | 0.0499785733994 | 0.333333333333 | FH | Disorders of the Krebs cycle |
Edges
| Protein 1 | Protein 2 | Score | Precision | Evidence |
|---|---|---|---|---|
| PGM1 | ALDH4A1 | 0.762 | 0.749 | fraction treiber_WMM |
| ALDH4A1 | FH | 0.738 | 0.738 | Guru fraction |
| PGM1 | FH | 0.0 | 0.001 | bioplex_WMM fraction |
Images
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Complex HuMAP2_02582 has an average edge precision of 0.496 which is ranked 2521 out of all 6965 complexes.
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