hu.MAP 2.0: Complex View
Human Protein Complex Map
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Complex: HuMAP2_02597
Confidence: Medium High
Proteins| Genename | Protein Name | Links |
|---|---|---|
| MORF4L1 | Mortality factor 4-like protein 1 (MORF-related gene 15 protein) (Protein MSL3-1) (Transcription factor-like protein MRG15) | UniProt NCBI |
| MRFAP1 | MORF4 family-associated protein 1 (Protein PGR1) (Protein associated with MRG of 14 kDa) | UniProt NCBI |
| ASH1L | Histone-lysine N-methyltransferase ASH1L (EC 2.1.1.43) (ASH1-like protein) (huASH1) (Absent small and homeotic disks protein 1 homolog) (Lysine N-methyltransferase 2H) | UniProt NCBI |
| MORF4L2 | Mortality factor 4-like protein 2 (MORF-related gene X protein) (Protein MSL3-2) (Transcription factor-like protein MRGX) | UniProt NCBI |
| PALB2 | Partner and localizer of BRCA2 | UniProt NCBI |
| MRFAP1L1 | MORF4 family-associated protein 1-like 1 | UniProt NCBI |
| EP400P1 | NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| CORUM:722 | 2.51655344529e-05 | 0.333333333333 | MRFAP1 MORF4L1 | MRG15-PAM14-RB complex |
| CORUM:723 | 2.51655344529e-05 | 0.333333333333 | MRFAP1 MORF4L1 | MRG15-PAM14-RB complex |
| CORUM:528 | 0.000878902571644 | 0.333333333333 | MORF4L2 MORF4L1 | NuA4/Tip60-HAT complex |
| CORUM:529 | 0.00100428015077 | 0.333333333333 | MORF4L2 MORF4L1 | NuA4/Tip60-HAT complex |
| REAC:R-HSA-3247509 | 0.0183482160149 | 0.5 | ASH1L MORF4L1 MORF4L2 | Chromatin modifying enzymes |
| REAC:R-HSA-4839726 | 0.0183482160149 | 0.5 | ASH1L MORF4L1 MORF4L2 | Chromatin organization |
| CORUM:724 | 0.0499726005494 | 0.166666666667 | MORF4L1 | MAF2 complex |
Edges
| Protein 1 | Protein 2 | Score | Precision | Evidence |
|---|---|---|---|---|
| MORF4L1 | EP400P1 | 1.0 | 0.949 | bioplex (MORF4L1) bioplex_WMM |
| MORF4L1 | MRFAP1L1 | 1.0 | 0.949 | bioplex (MORF4L1) bioplex_WMM |
| MORF4L1 | MORF4L2 | 0.994 | 0.92 | hein_WMM bioplex (MORF4L1,MORF4L2) bioplex_WMM |
| MRFAP1L1 | MORF4L2 | 0.945 | 0.856 | bioplex (MORF4L2) bioplex_WMM |
| MRFAP1 | MORF4L1 | 0.941 | 0.854 | bioplex (MORF4L1) bioplex_WMM |
| PALB2 | MORF4L1 | 0.925 | 0.843 | bioplex (MORF4L1) bioplex_WMM |
| EP400P1 | MORF4L2 | 0.742 | 0.739 | bioplex (MORF4L2) bioplex_WMM |
| MORF4L2 | ASH1L | 0.352 | 0.539 | hein_WMM bioplex (MORF4L2) bioplex_WMM |
| PALB2 | MORF4L2 | 0.261 | 0.482 | bioplex (MORF4L2) bioplex_WMM |
| MRFAP1 | MORF4L2 | 0.133 | 0.406 | bioplex (MORF4L2) bioplex_WMM |
| PALB2 | MRFAP1L1 | 0.012 | 0.149 | bioplex_WMM WMM_only |
| MRFAP1 | MRFAP1L1 | 0.011 | 0.14 | bioplex_WMM WMM_only |
| MRFAP1 | PALB2 | 0.011 | 0.14 | bioplex_WMM WMM_only |
| PALB2 | EP400P1 | 0.011 | 0.137 | bioplex_WMM WMM_only |
| EP400P1 | MRFAP1L1 | 0.011 | 0.137 | bioplex_WMM WMM_only |
| MRFAP1 | EP400P1 | 0.011 | 0.143 | bioplex_WMM WMM_only |
| PALB2 | ASH1L | 0.011 | 0.141 | bioplex_WMM WMM_only |
| MRFAP1L1 | ASH1L | 0.011 | 0.141 | bioplex_WMM WMM_only |
| MRFAP1 | ASH1L | 0.01 | 0.129 | bioplex_WMM WMM_only |
| EP400P1 | ASH1L | 0.01 | 0.126 | bioplex_WMM WMM_only |
| MORF4L1 | ASH1L | 0.0 | 0.003 | bioplex (MORF4L1) bioplex_WMM |
Images
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Complex HuMAP2_02597 has an average edge precision of 0.425 which is ranked 3075 out of all 6965 complexes.
Related Complexes
| Genename | Complexes |
|---|---|
| MORF4L1 | HuMAP2_00585 HuMAP2_00767 HuMAP2_01575 HuMAP2_02597 HuMAP2_04349 HuMAP2_04375 HuMAP2_04895 HuMAP2_06712 |
| MRFAP1 | HuMAP2_00585 HuMAP2_00767 HuMAP2_01575 HuMAP2_02597 HuMAP2_04375 HuMAP2_06712 |
| ASH1L | HuMAP2_02597 |
| MORF4L2 | HuMAP2_01575 HuMAP2_02597 HuMAP2_04895 HuMAP2_06712 |
| PALB2 | HuMAP2_00585 HuMAP2_00767 HuMAP2_01575 HuMAP2_02597 HuMAP2_04375 HuMAP2_06712 |
| MRFAP1L1 | HuMAP2_01575 HuMAP2_02597 HuMAP2_04895 HuMAP2_06712 |
| EP400P1 | HuMAP2_01575 HuMAP2_02597 HuMAP2_04895 HuMAP2_06712 HuMAP2_06963 |