hu.MAP 2.0: Complex View
Human Protein Complex Map
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Complex: HuMAP2_02605
Confidence: Medium
Proteins| Genename | Protein Name | Links |
|---|---|---|
| ZNF302 | Zinc finger protein 302 (Zinc finger protein 135-like) (Zinc finger protein 140-like) (Zinc finger protein 327) | UniProt NCBI |
| SALL1 | Sal-like protein 1 (Spalt-like transcription factor 1) (Zinc finger protein 794) (Zinc finger protein SALL1) (Zinc finger protein Spalt-1) (HSal1) (Sal-1) | UniProt NCBI |
| BRD2 | Bromodomain-containing protein 2 (O27.1.1) (Really interesting new gene 3 protein) | UniProt NCBI |
| BRD3 | Bromodomain-containing protein 3 (RING3-like protein) | UniProt NCBI |
| RFPL4A | Ret finger protein-like 4A (RING finger protein 210) | UniProt NCBI |
| RFPL4B | Ret finger protein-like 4B (RING finger protein 211) | UniProt NCBI |
| MTMR14 | Myotubularin-related protein 14 (EC 3.1.3.-) (HCV NS5A-transactivated protein 4 splice variant A-binding protein 1) (NS5ATP4ABP1) (hJumpy) | UniProt NCBI |
| GPC3 | Glypican-3 (GTR2-2) (Intestinal protein OCI-5) (MXR7) [Cleaved into: Glypican-3 alpha subunit; Glypican-3 beta subunit] | UniProt NCBI |
| ZNF195 | Zinc finger protein 195 | UniProt NCBI |
| CAMKV | CaM kinase-like vesicle-associated protein | UniProt NCBI |
| GPC1 | Glypican-1 [Cleaved into: Secreted glypican-1] | UniProt NCBI |
| FAM90A1 | Protein FAM90A1 | UniProt NCBI |
| FAM90A5P | NCBI | |
| FAM90A26 | NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| REAC:R-HSA-3656253 | 0.0130103194074 | 0.166666666667 | GPC1 GPC3 | Defective EXT1 causes exostoses 1, TRPS2 and CHDS |
| REAC:R-HSA-3656237 | 0.0130103194074 | 0.166666666667 | GPC1 GPC3 | Defective EXT2 causes exostoses 2 |
| REAC:R-HSA-4420332 | 0.024393293376 | 0.166666666667 | GPC1 GPC3 | Defective B3GALT6 causes EDSP2 and SEMDJL1 |
| REAC:R-HSA-3560801 | 0.024393293376 | 0.166666666667 | GPC1 GPC3 | Defective B3GAT3 causes JDSSDHD |
| REAC:R-HSA-3560783 | 0.024393293376 | 0.166666666667 | GPC1 GPC3 | Defective B4GALT7 causes EDS, progeroid type |
| REAC:R-HSA-2024096 | 0.0299298635014 | 0.166666666667 | GPC1 GPC3 | HS-GAG degradation |
| REAC:R-HSA-1971475 | 0.0392835928601 | 0.166666666667 | GPC1 GPC3 | A tetrasaccharide linker sequence is required for GAG synthesis |
Edges
| Protein 1 | Protein 2 | Score | Precision | Evidence |
|---|---|---|---|---|
| BRD3 | FAM90A1 | 1.0 | 0.949 | bioplex (FAM90A1) bioplex_WMM |
| FAM90A26 | FAM90A1 | 1.0 | 0.949 | bioplex (FAM90A1) bioplex_WMM |
| FAM90A5P | FAM90A1 | 1.0 | 0.949 | bioplex (FAM90A1) bioplex_WMM |
| FAM90A1 | BRD2 | 0.999 | 0.949 | bioplex (FAM90A1) bioplex_WMM |
| FAM90A1 | RFPL4B | 0.935 | 0.85 | bioplex (FAM90A1) bioplex_WMM |
| RFPL4B | RFPL4A | 0.229 | 0.469 | bioplex (RFPL4B) bioplex_WMM |
| ZNF302 | RFPL4B | 0.207 | 0.455 | bioplex (RFPL4B) bioplex_WMM |
| FAM90A1 | RFPL4A | 0.113 | 0.383 | bioplex (FAM90A1) bioplex_WMM |
| BRD3 | BRD2 | 0.102 | 0.365 | bioplex (BRD3) bioplex_WMM youn_WMM fraction |
| CAMKV | GPC1 | 0.065 | 0.347 | bioplex (CAMKV) bioplex_WMM |
| BRD2 | CAMKV | 0.052 | 0.301 | bioplex (CAMKV) bioplex_WMM |
| CAMKV | GPC3 | 0.048 | 0.294 | bioplex (CAMKV) bioplex_WMM |
| BRD3 | CAMKV | 0.045 | 0.285 | bioplex (CAMKV) bioplex_WMM |
| FAM90A1 | MTMR14 | 0.041 | 0.271 | bioplex (FAM90A1) bioplex_WMM |
| RFPL4B | SALL1 | 0.039 | 0.264 | bioplex (RFPL4B) bioplex_WMM |
| RFPL4B | ZNF195 | 0.028 | 0.23 | bioplex (RFPL4B) bioplex_WMM |
| GPC1 | GPC3 | 0.011 | 0.141 | bioplex_WMM WMM_only |
| FAM90A5P | FAM90A26 | 0.01 | 0.105 | bioplex_WMM WMM_only |
| FAM90A5P | RFPL4B | 0.009 | 0.108 | bioplex_WMM WMM_only |
| FAM90A26 | RFPL4A | 0.009 | 0.108 | bioplex_WMM WMM_only |
| FAM90A26 | MTMR14 | 0.009 | 0.108 | bioplex_WMM WMM_only |
| FAM90A26 | RFPL4B | 0.009 | 0.108 | bioplex_WMM WMM_only |
| FAM90A5P | RFPL4A | 0.009 | 0.108 | bioplex_WMM WMM_only |
| FAM90A5P | MTMR14 | 0.009 | 0.108 | bioplex_WMM WMM_only |
| FAM90A26 | BRD3 | 0.009 | 0.108 | bioplex_WMM WMM_only |
| FAM90A5P | BRD3 | 0.009 | 0.108 | bioplex_WMM WMM_only |
| MTMR14 | RFPL4A | 0.009 | 0.096 | bioplex_WMM WMM_only |
| RFPL4B | MTMR14 | 0.009 | 0.096 | bioplex_WMM WMM_only |
| FAM90A5P | BRD2 | 0.009 | 0.099 | bioplex_WMM WMM_only |
| FAM90A26 | BRD2 | 0.009 | 0.099 | bioplex_WMM WMM_only |
| BRD3 | MTMR14 | 0.009 | 0.099 | bioplex_WMM WMM_only |
| BRD3 | RFPL4A | 0.009 | 0.099 | bioplex_WMM WMM_only |
| BRD3 | RFPL4B | 0.009 | 0.099 | bioplex_WMM WMM_only |
| ZNF302 | RFPL4A | 0.009 | 0.098 | bioplex_WMM WMM_only |
| SALL1 | RFPL4A | 0.008 | 0.088 | bioplex_WMM WMM_only |
| BRD2 | RFPL4A | 0.008 | 0.086 | bioplex_WMM WMM_only |
| BRD2 | RFPL4B | 0.008 | 0.086 | bioplex_WMM WMM_only |
| BRD2 | MTMR14 | 0.008 | 0.086 | bioplex_WMM WMM_only |
| RFPL4A | ZNF195 | 0.008 | 0.086 | bioplex_WMM WMM_only |
| ZNF302 | SALL1 | 0.008 | 0.08 | bioplex_WMM WMM_only |
| ZNF302 | ZNF195 | 0.008 | 0.073 | bioplex_WMM WMM_only |
| SALL1 | ZNF195 | 0.008 | 0.04 | bioplex_WMM WMM_only |
| BRD3 | GPC1 | 0.008 | 0.011 | bioplex_WMM WMM_only |
| BRD2 | GPC1 | 0.007 | 0.003 | bioplex_WMM WMM_only |
| BRD3 | GPC3 | 0.007 | 0.007 | bioplex_WMM WMM_only |
| BRD2 | SALL1 | 0.007 | 0.007 | youn_WMM WMM_only |
| BRD2 | GPC3 | 0.007 | 0.004 | bioplex_WMM WMM_only |
| BRD3 | SALL1 | 0.007 | 0.004 | youn_WMM WMM_only |
Images
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Complex HuMAP2_02605 has an average edge precision of 0.226 which is ranked 5755 out of all 6965 complexes.
Related Complexes
| Genename | Complexes |
|---|---|
| ZNF302 | HuMAP2_01500 HuMAP2_01902 HuMAP2_02605 HuMAP2_04592 |
| SALL1 | HuMAP2_02605 |
| BRD2 | HuMAP2_01344 HuMAP2_02548 HuMAP2_02605 HuMAP2_06352 |
| BRD3 | HuMAP2_00321 HuMAP2_02548 HuMAP2_02605 HuMAP2_06352 |
| RFPL4A | HuMAP2_02605 HuMAP2_04592 |
| RFPL4B | HuMAP2_02605 HuMAP2_04592 |
| MTMR14 | HuMAP2_02605 HuMAP2_03945 |
| GPC3 | HuMAP2_02605 HuMAP2_04691 HuMAP2_04797 HuMAP2_06352 |
| ZNF195 | HuMAP2_02605 |
| CAMKV | HuMAP2_02605 HuMAP2_06352 |
| GPC1 | HuMAP2_02605 HuMAP2_04691 HuMAP2_04797 HuMAP2_06352 |
| FAM90A1 | HuMAP2_00321 HuMAP2_02548 HuMAP2_02605 HuMAP2_03945 |
| FAM90A5P | HuMAP2_00321 HuMAP2_02605 HuMAP2_03945 |
| FAM90A26 | HuMAP2_00321 HuMAP2_02605 HuMAP2_03945 |