hu.MAP 2.0: Complex View
Human Protein Complex Map
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Complex: HuMAP2_02608
Confidence: Medium
Proteins| Genename | Protein Name | Links |
|---|---|---|
| APIP | Methylthioribulose-1-phosphate dehydratase (MTRu-1-P dehydratase) (EC 4.2.1.109) (APAF1-interacting protein) (hAPIP) | UniProt NCBI |
| FASTKD2 | FAST kinase domain-containing protein 2, mitochondrial | UniProt NCBI |
| YARS2 | Tyrosine--tRNA ligase, mitochondrial (EC 6.1.1.1) (Tyrosyl-tRNA synthetase) (TyrRS) | UniProt NCBI |
| TRUB2 | Mitochondrial mRNA pseudouridine synthase TRUB2 (EC 5.4.99.-) | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| HP:0003546 | 0.0441507593067 | 0.5 | FASTKD2 YARS2 | Exercise intolerance |
| HP:0003800 | 0.0470133620262 | 0.5 | FASTKD2 YARS2 | Muscle abnormality related to mitochondrial dysfunction |
Edges
| Protein 1 | Protein 2 | Score | Precision | Evidence |
|---|---|---|---|---|
| APIP | FASTKD2 | 0.38 | 0.548 | bioplex (APIP) bioplex_WMM |
| TRUB2 | YARS2 | 0.055 | 0.309 | hein_WMM bioplex (TRUB2) bioplex_WMM |
| FASTKD2 | YARS2 | 0.035 | 0.261 | hein_WMM bioplex (FASTKD2) bioplex_WMM youn_WMM |
| TRUB2 | FASTKD2 | 0.025 | 0.211 | hein_WMM bioplex (FASTKD2) bioplex_WMM treiber_WMM |
Images
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Complex HuMAP2_02608 has an average edge precision of 0.332 which is ranked 4209 out of all 6965 complexes.
Related Complexes