hu.MAP 2.0: Complex View
Human Protein Complex Map
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Complex: HuMAP2_02613
Confidence: Medium High
Proteins| Genename | Protein Name | Links |
|---|---|---|
| CRYAB | Alpha-crystallin B chain (Alpha(B)-crystallin) (Heat shock protein beta-5) (HspB5) (Renal carcinoma antigen NY-REN-27) (Rosenthal fiber component) | UniProt NCBI |
| NYNRIN | Protein NYNRIN (NYN domain and retroviral integrase catalytic domain-containing protein) (Protein cousin of GIN1) | UniProt NCBI |
| NUDT16L1 | Tudor-interacting repair regulator protein (NUDT16-like protein 1) (Protein syndesmos) | UniProt NCBI |
| HSPB1 | Heat shock protein beta-1 (HspB1) (28 kDa heat shock protein) (Estrogen-regulated 24 kDa protein) (Heat shock 27 kDa protein) (HSP 27) (Stress-responsive protein 27) (SRP27) | UniProt NCBI |
| HSPB6 | Heat shock protein beta-6 (HspB6) (Heat shock 20 kDa-like protein p20) | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| HP:0002600 | 0.0127896924378 | 0.4 | HSPB1 CRYAB | Hyporeflexia of lower limbs |
| CORUM:6096 | 0.0499494897235 | 0.2 | CRYAB | alphaB-crystallin-Nav1.5 complex |
Edges
| Protein 1 | Protein 2 | Score | Precision | Evidence |
|---|---|---|---|---|
| CRYAB | HSPB1 | 0.993 | 0.918 | bioplex (CRYAB) bioplex_WMM fraction |
| CRYAB | NYNRIN | 0.379 | 0.549 | bioplex (CRYAB) bioplex_WMM |
| HSPB6 | HSPB1 | 0.316 | 0.51 | bioplex (HSPB6) bioplex_WMM |
| NUDT16L1 | CRYAB | 0.063 | 0.347 | bioplex (CRYAB) bioplex_WMM |
| NUDT16L1 | NYNRIN | 0.008 | 0.082 | bioplex_WMM WMM_only |
| NYNRIN | HSPB1 | 0.008 | 0.034 | bioplex_WMM WMM_only |
| NUDT16L1 | HSPB1 | 0.007 | 0.008 | bioplex_WMM WMM_only treiber_WMM |
Images
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Complex HuMAP2_02613 has an average edge precision of 0.35 which is ranked 3970 out of all 6965 complexes.
Related Complexes
| Genename | Complexes |
|---|---|
| CRYAB | HuMAP2_02613 HuMAP2_03201 HuMAP2_05639 HuMAP2_06316 |
| NYNRIN | HuMAP2_02613 HuMAP2_03201 HuMAP2_05639 |
| NUDT16L1 | HuMAP2_00715 HuMAP2_02613 |
| HSPB1 | HuMAP2_02613 HuMAP2_05639 HuMAP2_06316 |
| HSPB6 | HuMAP2_00689 HuMAP2_02613 HuMAP2_05639 HuMAP2_06990 |