hu.MAP 2.0: Complex View
Human Protein Complex Map
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Complex: HuMAP2_02622
Confidence: Medium
Proteins| Genename | Protein Name | Links |
|---|---|---|
| MAU2 | MAU2 chromatid cohesion factor homolog (MAU-2) (Cohesin loading complex subunit SCC4 homolog) | UniProt NCBI |
| NIPBL | Nipped-B-like protein (Delangin) (SCC2 homolog) | UniProt NCBI |
| ARFGAP1 | ADP-ribosylation factor GTPase-activating protein 1 (ARF GAP 1) (ADP-ribosylation factor 1 GTPase-activating protein) (ARF1 GAP) (ARF1-directed GTPase-activating protein) | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| REAC:R-HSA-2470946 | 0.000301184970683 | 0.666666666667 | MAU2 NIPBL | Cohesin Loading onto Chromatin |
| REAC:R-HSA-68884 | 0.00060895383853 | 0.666666666667 | MAU2 NIPBL | Mitotic Telophase/Cytokinesis |
| GO:0032116 | 0.00135247023414 | 0.666666666667 | MAU2 NIPBL | SMC loading complex |
| GO:0090694 | 0.00135247023414 | 0.666666666667 | MAU2 NIPBL | Scc2-Scc4 cohesin loading complex |
| GO:0071921 | 0.0135228859698 | 0.666666666667 | MAU2 NIPBL | cohesin loading |
| GO:0034085 | 0.0283955176165 | 0.666666666667 | MAU2 NIPBL | establishment of sister chromatid cohesion |
Edges
| Protein 1 | Protein 2 | Score | Precision | Evidence |
|---|---|---|---|---|
| MAU2 | NIPBL | 0.994 | 0.918 | hein_WMM bioplex_WMM hein (MAU2) Malo fraction |
| ARFGAP1 | MAU2 | 0.052 | 0.301 | bioplex (ARFGAP1) bioplex_WMM |
| ARFGAP1 | NIPBL | 0.009 | 0.095 | bioplex (ARFGAP1) bioplex_WMM youn_WMM |
Images
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Complex HuMAP2_02622 has an average edge precision of 0.438 which is ranked 2949 out of all 6965 complexes.
Related Complexes
| Genename | Complexes |
|---|---|
| MAU2 | HuMAP2_02622 HuMAP2_04695 |
| NIPBL | HuMAP2_02622 HuMAP2_04695 |
| ARFGAP1 | HuMAP2_02612 HuMAP2_02622 HuMAP2_03588 HuMAP2_03897 |