hu.MAP 2.0: Complex View
Human Protein Complex Map
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Complex: HuMAP2_02638
Confidence: Medium High
Proteins| Genename | Protein Name | Links |
|---|---|---|
| SHKBP1 | SH3KBP1-binding protein 1 (SETA-binding protein 1) | UniProt NCBI |
| FHL3 | Four and a half LIM domains protein 3 (FHL-3) (Skeletal muscle LIM-protein 2) (SLIM-2) | UniProt NCBI |
| HOXC6 | Homeobox protein Hox-C6 (Homeobox protein CP25) (Homeobox protein HHO.C8) (Homeobox protein Hox-3C) | UniProt NCBI |
| KCTD1 | BTB/POZ domain-containing protein KCTD1 (Potassium channel tetramerization domain-containing protein 1) | UniProt NCBI |
| KCTD3 | BTB/POZ domain-containing protein KCTD3 (Renal carcinoma antigen NY-REN-45) | UniProt NCBI |
| KCTD15 | BTB/POZ domain-containing protein KCTD15 (Potassium channel tetramerization domain-containing protein 15) | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| REAC:R-HSA-8866904 | 0.000797179114843 | 0.333333333333 | KCTD1 KCTD15 | Negative regulation of activity of TFAP2 (AP-2) family transcription factors |
| REAC:R-HSA-8864260 | 0.00895825109095 | 0.333333333333 | KCTD1 KCTD15 | Transcriptional regulation by the AP-2 (TFAP2) family of transcription factors |
| CORUM:3184 | 0.0249904952816 | 0.166666666667 | FHL3 | FHL3 homodimer complex |
| CORUM:3187 | 0.0499726005494 | 0.166666666667 | FHL3 | FHL2-FHL3 complex |
| CORUM:3190 | 0.0499726005494 | 0.166666666667 | FHL3 | FHL3-CREB complex |
Edges
| Protein 1 | Protein 2 | Score | Precision | Evidence |
|---|---|---|---|---|
| KCTD3 | FHL3 | 0.939 | 0.85 | bioplex (FHL3,KCTD3) bioplex_WMM youn_WMM |
| KCTD3 | KCTD1 | 0.714 | 0.728 | bioplex (KCTD3) bioplex_WMM |
| KCTD3 | KCTD15 | 0.554 | 0.646 | bioplex (KCTD3) bioplex_WMM |
| KCTD3 | SHKBP1 | 0.471 | 0.606 | bioplex (KCTD3,SHKBP1) bioplex_WMM youn_WMM boldt_WMM |
| FHL3 | HOXC6 | 0.351 | 0.537 | bioplex (FHL3) bioplex_WMM |
| SHKBP1 | FHL3 | 0.127 | 0.398 | bioplex (FHL3,SHKBP1) bioplex_WMM youn_WMM |
| SHKBP1 | KCTD1 | 0.008 | 0.066 | bioplex_WMM WMM_only |
| SHKBP1 | HOXC6 | 0.008 | 0.066 | bioplex_WMM WMM_only |
| KCTD15 | KCTD1 | 0.008 | 0.067 | bioplex_WMM WMM_only |
| KCTD3 | HOXC6 | 0.008 | 0.065 | bioplex_WMM WMM_only |
| KCTD15 | SHKBP1 | 0.007 | 0.012 | bioplex_WMM youn_WMM WMM_only |
| KCTD1 | FHL3 | 0.007 | 0.008 | bioplex_WMM WMM_only |
| KCTD15 | FHL3 | 0.007 | 0.007 | bioplex_WMM WMM_only |
Images
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Complex HuMAP2_02638 has an average edge precision of 0.312 which is ranked 4434 out of all 6965 complexes.
Related Complexes
| Genename | Complexes |
|---|---|
| SHKBP1 | HuMAP2_00381 HuMAP2_02638 |
| FHL3 | HuMAP2_01385 HuMAP2_02638 HuMAP2_03292 HuMAP2_03868 |
| HOXC6 | HuMAP2_01385 HuMAP2_02638 HuMAP2_03292 |
| KCTD1 | HuMAP2_00381 HuMAP2_02638 HuMAP2_05268 HuMAP2_06500 |
| KCTD3 | HuMAP2_00381 HuMAP2_02638 HuMAP2_05268 HuMAP2_06500 |
| KCTD15 | HuMAP2_00381 HuMAP2_02638 HuMAP2_04791 HuMAP2_05268 |