hu.MAP 2.0: Complex View
Human Protein Complex Map
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Complex: HuMAP2_02646
Confidence: Medium
Proteins| Genename | Protein Name | Links |
|---|---|---|
| H3-3A | Histone H3.3 | UniProt NCBI |
| OSER1 | Oxidative stress-responsive serine-rich protein 1 (Oxidative stress-responsive protein 1) (Peroxide-inducible transcript 1 protein) | UniProt NCBI |
| LACC1 | Laccase domain-containing protein 1 (Fatty acid metabolism-immunity nexus) | UniProt NCBI |
| PLP2 | Proteolipid protein 2 (Differentiation-dependent protein A4) (Intestinal membrane A4 protein) | UniProt NCBI |
| MSH6 | DNA mismatch repair protein Msh6 (hMSH6) (G/T mismatch-binding protein) (GTBP) (GTMBP) (MutS protein homolog 6) (MutS-alpha 160 kDa subunit) (p160) | UniProt NCBI |
| MEA1 | Male-enhanced antigen 1 (MEA-1) | UniProt NCBI |
| SGO2 | Shugoshin 2 (Shugoshin-2) (Shugoshin-like 2) (Tripin) | UniProt NCBI |
| H3-2 | NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| MIRNA:hsa-miR-324-5p | 0.0368617342826 | 0.5 | MSH6 LACC1 MEA1 | hsa-miR-324-5p |
| CORUM:374 | 0.0499726005494 | 0.166666666667 | MSH6 | MSH2-MSH6 complex |
| CORUM:1078 | 0.0499726005494 | 0.166666666667 | MSH6 | MSH2-MSH6 complex |
| CORUM:2740 | 0.0499726005494 | 0.166666666667 | MSH6 | MSH2-MSH6 complex |
Edges
| Protein 1 | Protein 2 | Score | Precision | Evidence |
|---|---|---|---|---|
| H3-3A | LACC1 | 0.943 | 0.856 | bioplex (LACC1) bioplex_WMM |
| H3-3A | SGO2 | 0.821 | 0.773 | bioplex (SGO2) bioplex_WMM |
| LACC1 | OSER1 | 0.604 | 0.672 | bioplex (LACC1,OSER1) bioplex_WMM |
| PLP2 | SGO2 | 0.089 | 0.352 | bioplex (SGO2) bioplex_WMM |
| PLP2 | LACC1 | 0.06 | 0.336 | bioplex (LACC1) bioplex_WMM |
| H3-2 | LACC1 | 0.056 | 0.315 | bioplex (LACC1) bioplex_WMM |
| MSH6 | H3-3A | 0.038 | 0.266 | hein_WMM hein (MSH6) |
| MSH6 | MEA1 | 0.022 | 0.205 | bioplex_WMM fraction |
| H3-3A | PLP2 | 0.012 | 0.149 | bioplex_WMM WMM_only |
| H3-3A | H3-2 | 0.01 | 0.105 | bioplex_WMM WMM_only |
| H3-2 | PLP2 | 0.009 | 0.112 | bioplex_WMM WMM_only |
| PLP2 | OSER1 | 0.008 | 0.089 | bioplex_WMM WMM_only |
| H3-3A | OSER1 | 0.008 | 0.083 | bioplex_WMM WMM_only |
| H3-2 | OSER1 | 0.007 | 0.012 | bioplex_WMM WMM_only |
| MSH6 | SGO2 | 0.007 | 0.0 | youn_WMM WMM_only boldt_WMM |
| MSH6 | PLP2 | 0.007 | 0.003 | gupta_WMM WMM_only |
| MSH6 | H3-2 | 0.007 | 0.002 | bioplex_WMM WMM_only |
| MEA1 | OSER1 | 0.007 | 0.0 | bioplex_WMM WMM_only |
| MEA1 | SGO2 | 0.007 | 0.0 | bioplex_WMM WMM_only |
| H3-2 | SGO2 | 0.0 | 0.009 | bioplex (SGO2) bioplex_WMM |
Images
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Complex HuMAP2_02646 has an average edge precision of 0.217 which is ranked 5910 out of all 6965 complexes.
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