hu.MAP 2.0: Complex View
Human Protein Complex Map
Search for a protein
Complex: HuMAP2_02657
Confidence: Very High
Proteins| Genename | Protein Name | Links |
|---|---|---|
| TRIM8 | E3 ubiquitin-protein ligase TRIM8 (EC 2.3.2.27) (Glioblastoma-expressed RING finger protein) (RING finger protein 27) (RING-type E3 ubiquitin transferase TRIM8) (Tripartite motif-containing protein 8) | UniProt NCBI |
| TRIM47 | E3 ubiquitin-protein ligase TRIM47 (EC 2.3.2.27) (Gene overexpressed in astrocytoma protein) (RING finger protein 100) (Tripartite motif-containing protein 47) | UniProt NCBI |
| KLHL3 | Kelch-like protein 3 | UniProt NCBI |
| KLHL2 | Kelch-like protein 2 (Actin-binding protein Mayven) | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| CORUM:6267 | 0.0499140284799 | 0.25 | KLHL3 | Ubiquitin E3 ligase (CUL3, KLHL3) |
Edges
| Protein 1 | Protein 2 | Score | Precision | Evidence |
|---|---|---|---|---|
| KLHL2 | TRIM8 | 0.941 | 0.854 | bioplex (KLHL2) bioplex_WMM |
| KLHL2 | KLHL3 | 0.917 | 0.84 | bioplex (KLHL2) bioplex_WMM |
| KLHL2 | TRIM47 | 0.728 | 0.735 | bioplex (KLHL2) bioplex_WMM |
| KLHL3 | TRIM8 | 0.009 | 0.095 | bioplex_WMM WMM_only |
| KLHL3 | TRIM47 | 0.008 | 0.091 | bioplex_WMM WMM_only |
| TRIM8 | TRIM47 | 0.008 | 0.091 | bioplex_WMM WMM_only |
Images
Click to enlarge
Complex HuMAP2_02657 has an average edge precision of 0.451 which is ranked 2866 out of all 6965 complexes.
Related Complexes
| Genename | Complexes |
|---|---|
| TRIM8 | HuMAP2_02657 HuMAP2_02675 |
| TRIM47 | HuMAP2_02657 HuMAP2_02675 HuMAP2_06989 |
| KLHL3 | HuMAP2_02657 HuMAP2_02675 |
| KLHL2 | HuMAP2_02657 HuMAP2_02675 |