hu.MAP 2.0: Complex View
Human Protein Complex Map
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Complex: HuMAP2_02665
Confidence: Extremely High
Proteins| Genename | Protein Name | Links |
|---|---|---|
| PFDN2 | Prefoldin subunit 2 | UniProt NCBI |
| PFDN6 | Prefoldin subunit 6 (Protein Ke2) | UniProt NCBI |
| PFDN5 | Prefoldin subunit 5 (Myc modulator 1) (c-Myc-binding protein Mm-1) | UniProt NCBI |
| PFDN1 | Prefoldin subunit 1 | UniProt NCBI |
| PFDN4 | Prefoldin subunit 4 (Protein C-1) | UniProt NCBI |
| VBP1 | Prefoldin subunit 3 (HIBBJ46) (von Hippel-Lindau-binding protein 1) (VBP-1) (VHL-binding protein 1) | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| CORUM:33 | 4.09578169876e-21 | 1.0 | PFDN1 PFDN5 PFDN4 VBP1 PFDN2 PFDN6 | Prefoldin complex |
| CORUM:112 | 4.09578169876e-21 | 1.0 | PFDN1 PFDN5 PFDN4 VBP1 PFDN2 PFDN6 | Prefoldin complex |
| REAC:R-HSA-389957 | 3.2038958248e-15 | 1.0 | PFDN1 PFDN5 PFDN4 VBP1 PFDN2 PFDN6 | Prefoldin mediated transfer of substrate to CCT/TriC |
| REAC:R-HSA-389958 | 7.96921597844e-15 | 1.0 | PFDN1 PFDN5 PFDN4 VBP1 PFDN2 PFDN6 | Cooperation of Prefoldin and TriC/CCT in actin and tubulin folding |
| GO:0016272 | 4.91515675326e-14 | 0.833333333333 | PFDN2 PFDN6 PFDN5 PFDN4 VBP1 | prefoldin complex |
| REAC:R-HSA-390466 | 6.73893589242e-12 | 1.0 | PFDN1 PFDN5 PFDN4 VBP1 PFDN2 PFDN6 | Chaperonin-mediated protein folding |
| REAC:R-HSA-391251 | 1.00340062517e-11 | 1.0 | PFDN1 PFDN5 PFDN4 VBP1 PFDN2 PFDN6 | Protein folding |
| REAC:R-HSA-392499 | 0.000522475750064 | 1.0 | PFDN1 PFDN5 PFDN4 VBP1 PFDN2 PFDN6 | Metabolism of proteins |
| CORUM:0000000 | 0.0090785708022 | 1.0 | PFDN1 PFDN5 PFDN4 VBP1 PFDN2 PFDN6 | CORUM root |
Edges
| Protein 1 | Protein 2 | Score | Precision | Evidence |
|---|---|---|---|---|
| VBP1 | PFDN1 | 1.0 | 0.949 | hein_WMM bioplex (VBP1) bioplex_WMM Guru boldt youn_WMM hein (VBP1) gupta_WMM fraction boldt_WMM |
| PFDN2 | PFDN5 | 1.0 | 0.949 | hein_WMM bioplex (PFDN2) bioplex_WMM Guru boldt youn_WMM hein (PFDN2) gupta_WMM fraction boldt_WMM |
| VBP1 | PFDN4 | 1.0 | 0.949 | hein_WMM bioplex (PFDN4,VBP1) bioplex_WMM Guru boldt youn_WMM hein (VBP1) gupta_WMM fraction boldt_WMM |
| PFDN2 | VBP1 | 1.0 | 0.949 | hein_WMM bioplex (PFDN2,VBP1) bioplex_WMM Guru boldt youn_WMM hein (PFDN2,VBP1) gupta_WMM fraction boldt_WMM |
| VBP1 | PFDN6 | 1.0 | 0.949 | hein_WMM bioplex (VBP1) bioplex_WMM Guru boldt youn_WMM hein (VBP1) gupta_WMM fraction boldt_WMM |
| PFDN2 | PFDN1 | 1.0 | 0.949 | hein_WMM bioplex (PFDN2) bioplex_WMM Guru boldt youn_WMM hein (PFDN2) gupta_WMM fraction boldt_WMM |
| PFDN5 | PFDN6 | 1.0 | 0.949 | hein_WMM bioplex_WMM Guru boldt youn_WMM gupta_WMM fraction boldt_WMM |
| PFDN4 | PFDN6 | 1.0 | 0.949 | hein_WMM bioplex (PFDN4) bioplex_WMM Guru boldt youn_WMM gupta_WMM fraction boldt_WMM |
| PFDN2 | PFDN6 | 1.0 | 0.949 | hein_WMM bioplex (PFDN2) bioplex_WMM Guru boldt youn_WMM hein (PFDN2) Malo gupta_WMM fraction boldt_WMM |
| VBP1 | PFDN5 | 1.0 | 0.949 | hein_WMM bioplex (VBP1) bioplex_WMM Guru boldt youn_WMM hein (VBP1) gupta_WMM fraction boldt_WMM |
| PFDN2 | PFDN4 | 1.0 | 0.949 | hein_WMM bioplex (PFDN2,PFDN4) bioplex_WMM Guru boldt youn_WMM hein (PFDN2) gupta_WMM fraction boldt_WMM |
| PFDN4 | PFDN5 | 1.0 | 0.949 | hein_WMM bioplex (PFDN4) bioplex_WMM Guru boldt youn_WMM gupta_WMM fraction boldt_WMM |
| PFDN1 | PFDN5 | 1.0 | 0.949 | hein_WMM bioplex_WMM Guru boldt youn_WMM gupta_WMM fraction boldt_WMM |
| PFDN1 | PFDN6 | 1.0 | 0.949 | hein_WMM bioplex_WMM Guru boldt youn_WMM gupta_WMM fraction boldt_WMM |
| PFDN4 | PFDN1 | 0.999 | 0.949 | hein_WMM bioplex (PFDN4) bioplex_WMM Guru boldt youn_WMM gupta_WMM fraction boldt_WMM |
Images
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Complex HuMAP2_02665 has an average edge precision of 0.949 which is ranked 5 out of all 6965 complexes.
Related Complexes
| Genename | Complexes |
|---|---|
| PFDN2 | HuMAP2_01751 HuMAP2_02328 HuMAP2_02428 HuMAP2_02665 HuMAP2_02988 HuMAP2_03507 |
| PFDN6 | HuMAP2_02428 HuMAP2_02665 HuMAP2_02988 |
| PFDN5 | HuMAP2_02428 HuMAP2_02665 HuMAP2_02988 HuMAP2_05617 |
| PFDN1 | HuMAP2_02428 HuMAP2_02665 HuMAP2_02988 |
| PFDN4 | HuMAP2_02428 HuMAP2_02665 HuMAP2_02988 HuMAP2_06252 |
| VBP1 | HuMAP2_02428 HuMAP2_02665 HuMAP2_02988 |