hu.MAP 2.0: Complex View
Human Protein Complex Map
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Complex: HuMAP2_02667
Confidence: Very High
Proteins| Genename | Protein Name | Links |
|---|---|---|
| GSR | Glutathione reductase, mitochondrial (GR) (GRase) (EC 1.8.1.7) | UniProt NCBI |
| AKR1A1 | Aldo-keto reductase family 1 member A1 (EC 1.1.1.2) (EC 1.1.1.372) (EC 1.1.1.54) (Alcohol dehydrogenase [NADP(+)]) (Aldehyde reductase) (Glucuronate reductase) (EC 1.1.1.19) (Glucuronolactone reductase) (EC 1.1.1.20) | UniProt NCBI |
| UPP1 | Uridine phosphorylase 1 (UPase 1) (UrdPase 1) (EC 2.4.2.3) | UniProt NCBI |
| HIBCH | 3-hydroxyisobutyryl-CoA hydrolase, mitochondrial (EC 3.1.2.4) (3-hydroxyisobutyryl-coenzyme A hydrolase) (HIB-CoA hydrolase) (HIBYL-CoA-H) | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| KEGG:01100 | 0.00203701694021 | 1.0 | AKR1A1 UPP1 GSR HIBCH | Metabolic pathways |
| WP:WP3925 | 0.0063819591539 | 0.5 | GSR HIBCH | Amino Acid metabolism |
| WP:WP702 | 0.0208080933183 | 0.5 | GSR AKR1A1 | Metapathway biotransformation Phase I and II |
Edges
| Protein 1 | Protein 2 | Score | Precision | Evidence |
|---|---|---|---|---|
| GSR | AKR1A1 | 1.0 | 0.949 | bioplex_WMM fraction treiber_WMM |
| AKR1A1 | HIBCH | 0.99 | 0.907 | bioplex_WMM fraction |
| GSR | HIBCH | 0.972 | 0.885 | bioplex_WMM fraction |
| UPP1 | AKR1A1 | 0.765 | 0.749 | fraction |
| UPP1 | GSR | 0.007 | 0.001 | bioplex_WMM WMM_only treiber_WMM |
Images
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Complex HuMAP2_02667 has an average edge precision of 0.698 which is ranked 1376 out of all 6965 complexes.
Related Complexes
| Genename | Complexes |
|---|---|
| GSR | HuMAP2_00363 HuMAP2_01741 HuMAP2_02667 HuMAP2_04952 HuMAP2_06138 |
| AKR1A1 | HuMAP2_00919 HuMAP2_01741 HuMAP2_02667 HuMAP2_06546 |
| UPP1 | HuMAP2_00244 HuMAP2_02667 HuMAP2_04018 HuMAP2_04478 HuMAP2_04494 HuMAP2_04550 HuMAP2_06910 |
| HIBCH | HuMAP2_02667 HuMAP2_02827 |