hu.MAP 2.0: Complex View
Human Protein Complex Map
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Complex: HuMAP2_02673
Confidence: High
Proteins| Genename | Protein Name | Links |
|---|---|---|
| GGNBP2 | Gametogenetin-binding protein 2 (Laryngeal carcinoma-related protein 1) (Protein ZNF403) | UniProt NCBI |
| FBLN1 | Fibulin-1 (FIBL-1) | UniProt NCBI |
| LDLR | Low-density lipoprotein receptor (LDL receptor) | UniProt NCBI |
| ZFP41 | Zinc finger protein 41 homolog (Zfp-41) | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| WP:WP2846 | 0.0166793461628 | 0.25 | LDLR | Proprotein convertase subtilisin/kexin type 9 (PCSK9) mediated LDL receptor degradation |
| WP:WP3408 | 0.0166793461628 | 0.25 | LDLR | Evolocumab Mechanism |
Edges
| Protein 1 | Protein 2 | Score | Precision | Evidence |
|---|---|---|---|---|
| ZFP41 | FBLN1 | 0.712 | 0.728 | bioplex (ZFP41) bioplex_WMM |
| GGNBP2 | ZFP41 | 0.609 | 0.674 | bioplex (ZFP41) bioplex_WMM |
| LDLR | ZFP41 | 0.578 | 0.66 | bioplex (ZFP41) bioplex_WMM |
| GGNBP2 | LDLR | 0.008 | 0.008 | bioplex_WMM WMM_only |
| GGNBP2 | FBLN1 | 0.007 | 0.012 | bioplex_WMM WMM_only |
| LDLR | FBLN1 | 0.007 | 0.009 | bioplex_WMM WMM_only |
Images
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Complex HuMAP2_02673 has an average edge precision of 0.349 which is ranked 3992 out of all 6965 complexes.
Related Complexes
| Genename | Complexes |
|---|---|
| GGNBP2 | HuMAP2_01082 HuMAP2_02673 HuMAP2_04155 HuMAP2_05261 |
| FBLN1 | HuMAP2_02647 HuMAP2_02673 HuMAP2_04155 |
| LDLR | HuMAP2_01127 HuMAP2_02673 HuMAP2_04155 |
| ZFP41 | HuMAP2_02647 HuMAP2_02673 HuMAP2_04155 |