hu.MAP 2.0: Complex View
Human Protein Complex Map
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Complex: HuMAP2_02686
Confidence: Very High
Proteins| Genename | Protein Name | Links |
|---|---|---|
| HSD17B14 | 17-beta-hydroxysteroid dehydrogenase 14 (17-beta-HSD 14) (EC 1.1.1.-) (17-beta-hydroxysteroid dehydrogenase DHRS10) (Dehydrogenase/reductase SDR family member 10) (Retinal short-chain dehydrogenase/reductase retSDR3) (Short chain dehydrogenase/reductase family 47C member 1) | UniProt NCBI |
| TALDO1 | Transaldolase (EC 2.2.1.2) | UniProt NCBI |
| PGLS | 6-phosphogluconolactonase (6PGL) (EC 3.1.1.31) | UniProt NCBI |
| PPIAL4D | Peptidyl-prolyl cis-trans isomerase A-like 4D (PPIase A-like 4D) (EC 5.2.1.8) | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| WP:WP134 | 3.52660392509e-05 | 0.5 | PGLS TALDO1 | Pentose Phosphate Metabolism |
| KEGG:00030 | 0.000811520562786 | 0.5 | PGLS TALDO1 | Pentose phosphate pathway |
| REAC:R-HSA-71336 | 0.000914071346391 | 0.5 | PGLS TALDO1 | Pentose phosphate pathway |
| KEGG:01200 | 0.012776519361 | 0.5 | PGLS TALDO1 | Carbon metabolism |
| REAC:R-HSA-6791462 | 0.0499190562503 | 0.25 | TALDO1 | TALDO1 deficiency: failed conversion of Fru(6)P, E4P to SH7P, GA3P |
| REAC:R-HSA-6791055 | 0.0499190562503 | 0.25 | TALDO1 | TALDO1 deficiency: failed conversion of SH7P, GA3P to Fru(6)P, E4P |
Edges
| Protein 1 | Protein 2 | Score | Precision | Evidence |
|---|---|---|---|---|
| HSD17B14 | TALDO1 | 0.939 | 0.851 | fraction |
| TALDO1 | PPIAL4D | 0.875 | 0.809 | fraction |
| TALDO1 | PGLS | 0.853 | 0.791 | bioplex (TALDO1) bioplex_WMM fraction |
| HSD17B14 | PGLS | 0.0 | 0.002 | fraction |
Images
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Complex HuMAP2_02686 has an average edge precision of 0.613 which is ranked 1871 out of all 6965 complexes.
Related Complexes
| Genename | Complexes |
|---|---|
| HSD17B14 | HuMAP2_00175 HuMAP2_00664 HuMAP2_02686 HuMAP2_05316 HuMAP2_06328 |
| TALDO1 | HuMAP2_00823 HuMAP2_02686 HuMAP2_05233 HuMAP2_05571 |
| PGLS | HuMAP2_02162 HuMAP2_02686 HuMAP2_04037 HuMAP2_04049 HuMAP2_05296 HuMAP2_05643 |
| PPIAL4D | HuMAP2_01741 HuMAP2_02686 HuMAP2_06602 HuMAP2_06910 |