hu.MAP 2.0: Complex View
Human Protein Complex Map
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Complex: HuMAP2_02699
Confidence: Very High
Proteins| Genename | Protein Name | Links |
|---|---|---|
| EMC8 | ER membrane protein complex subunit 8 (Neighbor of COX4) (Protein FAM158B) | UniProt NCBI |
| EMC7 | ER membrane protein complex subunit 7 | UniProt NCBI |
| EMC10 | ER membrane protein complex subunit 10 (Hematopoietic signal peptide-containing membrane domain-containing protein 1) | UniProt NCBI |
| EMC4 | ER membrane protein complex subunit 4 (Cell proliferation-inducing gene 17 protein) (Transmembrane protein 85) | UniProt NCBI |
| MMGT1 | Membrane magnesium transporter 1 (ER membrane protein complex subunit 5) (Transmembrane protein 32) | UniProt NCBI |
| EMC1 | ER membrane protein complex subunit 1 | UniProt NCBI |
| EMC2 | ER membrane protein complex subunit 2 (Tetratricopeptide repeat protein 35) (TPR repeat protein 35) | UniProt NCBI |
| EMC3 | ER membrane protein complex subunit 3 (Transmembrane protein 111) | UniProt NCBI |
| EMC6 | ER membrane protein complex subunit 6 (Transmembrane protein 93) | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| GO:0072546 | 5.04290534095e-27 | 1.0 | EMC6 EMC8 EMC4 EMC2 EMC3 MMGT1 EMC7 EMC1 EMC10 | ER membrane protein complex |
| GO:0030176 | 9.61314018901e-15 | 1.0 | EMC6 EMC8 EMC4 EMC2 EMC3 MMGT1 EMC7 EMC1 EMC10 | integral component of endoplasmic reticulum membrane |
| GO:0031227 | 1.47108154718e-14 | 1.0 | EMC6 EMC8 EMC4 EMC2 EMC3 MMGT1 EMC7 EMC1 EMC10 | intrinsic component of endoplasmic reticulum membrane |
| GO:0031301 | 6.11250555903e-12 | 1.0 | EMC6 EMC8 EMC4 EMC2 EMC3 MMGT1 EMC7 EMC1 EMC10 | integral component of organelle membrane |
| GO:0031300 | 1.17005634816e-11 | 1.0 | EMC6 EMC8 EMC4 EMC2 EMC3 MMGT1 EMC7 EMC1 EMC10 | intrinsic component of organelle membrane |
| GO:0005789 | 3.63095613755e-08 | 1.0 | EMC6 EMC8 EMC4 EMC2 EMC3 MMGT1 EMC7 EMC1 EMC10 | endoplasmic reticulum membrane |
| GO:0042175 | 4.20684668442e-08 | 1.0 | EMC6 EMC8 EMC4 EMC2 EMC3 MMGT1 EMC7 EMC1 EMC10 | nuclear outer membrane-endoplasmic reticulum membrane network |
| GO:0098796 | 3.65145237997e-07 | 1.0 | EMC6 EMC8 EMC4 EMC2 EMC3 MMGT1 EMC7 EMC1 EMC10 | membrane protein complex |
| GO:0044432 | 6.18611442372e-07 | 1.0 | EMC6 EMC8 EMC4 EMC2 EMC3 MMGT1 EMC7 EMC1 EMC10 | endoplasmic reticulum part |
| GO:0005783 | 1.56807560541e-05 | 1.0 | EMC6 EMC8 EMC4 EMC2 EMC3 MMGT1 EMC7 EMC1 EMC10 | endoplasmic reticulum |
| GO:0016021 | 0.000122576181806 | 1.0 | EMC6 EMC8 EMC4 EMC2 EMC3 MMGT1 EMC7 EMC1 EMC10 | integral component of membrane |
| GO:0031224 | 0.000178357129028 | 1.0 | EMC6 EMC8 EMC4 EMC2 EMC3 MMGT1 EMC7 EMC1 EMC10 | intrinsic component of membrane |
| GO:0031090 | 0.00246412233577 | 1.0 | EMC6 EMC8 EMC4 EMC2 EMC3 MMGT1 EMC7 EMC1 EMC10 | organelle membrane |
| MIRNA:hsa-miR-5089-5p | 0.00775236217124 | 0.444444444444 | EMC3 EMC7 EMC10 EMC1 | hsa-miR-5089-5p |
| GO:0044425 | 0.0305435489729 | 1.0 | EMC6 EMC8 EMC4 EMC2 EMC3 MMGT1 EMC7 EMC1 EMC10 | membrane part |
| GO:0012505 | 0.0445398812368 | 1.0 | EMC6 EMC8 EMC4 EMC2 EMC3 MMGT1 EMC7 EMC1 EMC10 | endomembrane system |
Edges
| Protein 1 | Protein 2 | Score | Precision | Evidence |
|---|---|---|---|---|
| EMC3 | EMC2 | 1.0 | 0.949 | hein_WMM bioplex (EMC2,EMC3) bioplex_WMM youn_WMM hein (EMC2,EMC3) gupta_WMM |
| EMC7 | EMC2 | 1.0 | 0.949 | hein_WMM bioplex (EMC2,EMC7) bioplex_WMM youn_WMM hein (EMC2) gupta_WMM |
| EMC8 | EMC2 | 1.0 | 0.949 | hein_WMM bioplex (EMC2) bioplex_WMM youn_WMM hein (EMC2) gupta_WMM |
| MMGT1 | EMC2 | 1.0 | 0.949 | hein_WMM bioplex (EMC2) bioplex_WMM youn_WMM hein (EMC2,MMGT1) gupta_WMM |
| EMC4 | EMC2 | 1.0 | 0.949 | hein_WMM bioplex (EMC2) bioplex_WMM youn_WMM hein (EMC2) gupta_WMM |
| EMC1 | EMC2 | 1.0 | 0.949 | hein_WMM bioplex (EMC2) bioplex_WMM youn_WMM hein (EMC1,EMC2) gupta_WMM |
| EMC10 | EMC2 | 1.0 | 0.949 | hein_WMM bioplex (EMC2) bioplex_WMM youn_WMM hein (EMC2) gupta_WMM |
| EMC7 | EMC3 | 1.0 | 0.949 | hein_WMM bioplex (EMC3,EMC7) bioplex_WMM youn_WMM hein (EMC3) gupta_WMM |
| EMC7 | EMC1 | 1.0 | 0.949 | hein_WMM bioplex (EMC7) bioplex_WMM youn_WMM hein (EMC1) gupta_WMM fraction |
| EMC1 | EMC3 | 1.0 | 0.949 | hein_WMM bioplex (EMC3) bioplex_WMM youn_WMM hein (EMC1,EMC3) gupta_WMM |
| EMC4 | EMC3 | 1.0 | 0.949 | hein_WMM bioplex (EMC3) bioplex_WMM youn_WMM hein (EMC3) gupta_WMM |
| MMGT1 | EMC3 | 0.998 | 0.944 | hein_WMM bioplex (EMC3) bioplex_WMM youn_WMM hein (EMC3,MMGT1) gupta_WMM |
| EMC8 | EMC3 | 0.992 | 0.912 | hein_WMM bioplex_WMM youn_WMM hein (EMC3) gupta_WMM |
| EMC7 | MMGT1 | 0.939 | 0.852 | hein_WMM bioplex (EMC7) bioplex_WMM youn_WMM hein (MMGT1) gupta_WMM |
| EMC2 | EMC6 | 0.922 | 0.843 | hein_WMM bioplex (EMC2) bioplex_WMM youn_WMM hein (EMC6) gupta_WMM |
| EMC8 | MMGT1 | 0.92 | 0.843 | hein_WMM bioplex_WMM youn_WMM hein (MMGT1) gupta_WMM |
| EMC8 | EMC1 | 0.91 | 0.834 | hein_WMM bioplex_WMM youn_WMM hein (EMC1) gupta_WMM |
| EMC7 | EMC8 | 0.825 | 0.774 | hein_WMM bioplex (EMC7) bioplex_WMM youn_WMM gupta_WMM |
| EMC4 | EMC6 | 0.813 | 0.773 | hein_WMM bioplex_WMM youn_WMM hein (EMC6) gupta_WMM |
| EMC4 | MMGT1 | 0.798 | 0.764 | hein_WMM bioplex_WMM youn_WMM hein (MMGT1) gupta_WMM |
| EMC4 | EMC1 | 0.792 | 0.758 | hein_WMM bioplex_WMM youn_WMM hein (EMC1) gupta_WMM |
| MMGT1 | EMC10 | 0.756 | 0.747 | hein_WMM bioplex_WMM youn_WMM hein (MMGT1) gupta_WMM |
| MMGT1 | EMC6 | 0.736 | 0.738 | hein_WMM bioplex_WMM youn_WMM hein (EMC6) gupta_WMM |
| EMC4 | EMC7 | 0.728 | 0.735 | hein_WMM bioplex (EMC7) bioplex_WMM youn_WMM gupta_WMM |
| EMC8 | EMC6 | 0.716 | 0.73 | hein_WMM bioplex_WMM youn_WMM hein (EMC6) gupta_WMM |
| EMC10 | EMC3 | 0.656 | 0.694 | hein_WMM bioplex (EMC3) bioplex_WMM youn_WMM gupta_WMM |
| MMGT1 | EMC1 | 0.638 | 0.686 | hein_WMM bioplex_WMM youn_WMM hein (EMC1,MMGT1) gupta_WMM |
| EMC10 | EMC1 | 0.511 | 0.63 | hein_WMM bioplex_WMM youn_WMM hein (EMC1) gupta_WMM |
| EMC7 | EMC10 | 0.482 | 0.613 | hein_WMM bioplex (EMC7) bioplex_WMM youn_WMM gupta_WMM |
| EMC10 | EMC6 | 0.432 | 0.578 | hein_WMM bioplex_WMM youn_WMM hein (EMC6) gupta_WMM |
| EMC7 | EMC6 | 0.144 | 0.407 | hein_WMM bioplex_WMM youn_WMM hein (EMC6) gupta_WMM |
| EMC3 | EMC6 | 0.072 | 0.356 | hein_WMM bioplex_WMM youn_WMM hein (EMC6) gupta_WMM |
| EMC4 | EMC8 | 0.056 | 0.312 | hein_WMM bioplex_WMM youn_WMM gupta_WMM WMM_only |
| EMC4 | EMC10 | 0.032 | 0.242 | hein_WMM bioplex_WMM youn_WMM gupta_WMM WMM_only |
| EMC8 | EMC10 | 0.024 | 0.212 | hein_WMM bioplex_WMM youn_WMM gupta_WMM WMM_only |
| EMC1 | EMC6 | 0.008 | 0.06 | bioplex_WMM youn_WMM gupta_WMM WMM_only |
Images
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Complex HuMAP2_02699 has an average edge precision of 0.735 which is ranked 1234 out of all 6965 complexes.
Related Complexes
| Genename | Complexes |
|---|---|
| EMC8 | HuMAP2_00132 HuMAP2_02699 |
| EMC7 | HuMAP2_00132 HuMAP2_02699 |
| EMC10 | HuMAP2_00132 HuMAP2_02699 |
| EMC4 | HuMAP2_00132 HuMAP2_02699 |
| MMGT1 | HuMAP2_00132 HuMAP2_01365 HuMAP2_02699 |
| EMC1 | HuMAP2_00132 HuMAP2_02699 |
| EMC2 | HuMAP2_00132 HuMAP2_02699 HuMAP2_04941 |
| EMC3 | HuMAP2_00132 HuMAP2_02699 |
| EMC6 | HuMAP2_00132 HuMAP2_02699 |