hu.MAP 2.0: Complex View
Human Protein Complex Map
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Complex: HuMAP2_02703
Confidence: Medium High
Proteins| Genename | Protein Name | Links |
|---|---|---|
| DNPEP | Aspartyl aminopeptidase (EC 3.4.11.21) | UniProt NCBI |
| PGM2 | Phosphoglucomutase-2 (PGM 2) (EC 5.4.2.2) (Glucose phosphomutase 2) (Phosphodeoxyribomutase) (Phosphopentomutase) (EC 5.4.2.7) | UniProt NCBI |
| TXNDC17 | Thioredoxin domain-containing protein 17 (14 kDa thioredoxin-related protein) (TRP14) (Protein 42-9-9) (Thioredoxin-like protein 5) | UniProt NCBI |
| PGD | 6-phosphogluconate dehydrogenase, decarboxylating (EC 1.1.1.44) | UniProt NCBI |
| SARS | Serine--tRNA ligase, cytoplasmic (EC 6.1.1.11) (Seryl-tRNA synthetase) (SerRS) (Seryl-tRNA(Ser/Sec) synthetase) | UniProt NCBI |
| HAAO | 3-hydroxyanthranilate 3,4-dioxygenase (EC 1.13.11.6) (3-hydroxyanthranilate oxygenase) (3-HAO) (h3HAO) (3-hydroxyanthranilic acid dioxygenase) (HAD) | UniProt NCBI |
| SUCLG1 | Succinate--CoA ligase [ADP/GDP-forming] subunit alpha, mitochondrial (EC 6.2.1.4) (EC 6.2.1.5) (Succinyl-CoA synthetase subunit alpha) (SCS-alpha) | UniProt NCBI |
| FAH | Fumarylacetoacetase (FAA) (EC 3.7.1.2) (Beta-diketonase) (Fumarylacetoacetate hydrolase) | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| REAC:R-HSA-71336 | 0.00406028611704 | 0.25 | PGD PGM2 | Pentose phosphate pathway |
| KEGG:00030 | 0.00489222565408 | 0.25 | PGD PGM2 | Pentose phosphate pathway |
| KEGG:01100 | 0.0101915709661 | 0.625 | SUCLG1 PGD FAH HAAO PGM2 | Metabolic pathways |
| REAC:R-HSA-1430728 | 0.0157286835681 | 0.75 | HAAO SUCLG1 FAH SARS PGD PGM2 | Metabolism |
| WP:WP3925 | 0.0477902143581 | 0.25 | SUCLG1 FAH | Amino Acid metabolism |
| CORUM:393 | 0.0497224828424 | 0.125 | SUCLG1 | Succinyl-CoA synthetase, GDP-forming |
| CORUM:394 | 0.0497224828424 | 0.125 | SUCLG1 | Succinyl-CoA synthetase, ADP-forming |
Edges
| Protein 1 | Protein 2 | Score | Precision | Evidence |
|---|---|---|---|---|
| PGM2 | FAH | 0.849 | 0.79 | bioplex_WMM fraction |
| SARS | FAH | 0.812 | 0.771 | bioplex_WMM fraction |
| PGM2 | DNPEP | 0.373 | 0.546 | fraction |
| PGM2 | HAAO | 0.343 | 0.533 | fraction |
| PGM2 | SUCLG1 | 0.297 | 0.496 | bioplex_WMM fraction |
| SARS | PGD | 0.293 | 0.494 | bioplex_WMM Guru gupta_WMM fraction boldt_WMM treiber_WMM |
| FAH | PGD | 0.251 | 0.474 | bioplex_WMM fraction treiber_WMM |
| TXNDC17 | PGD | 0.19 | 0.442 | bioplex_WMM fraction |
| SARS | DNPEP | 0.179 | 0.438 | fraction |
| FAH | DNPEP | 0.119 | 0.392 | fraction |
| HAAO | PGD | 0.083 | 0.349 | fraction |
| TXNDC17 | PGM2 | 0.064 | 0.347 | bioplex_WMM fraction |
| FAH | HAAO | 0.063 | 0.347 | fraction |
| TXNDC17 | HAAO | 0.054 | 0.299 | fraction |
| PGM2 | PGD | 0.053 | 0.298 | bioplex_WMM fraction |
| TXNDC17 | SARS | 0.046 | 0.292 | bioplex_WMM fraction |
| TXNDC17 | SUCLG1 | 0.028 | 0.23 | bioplex_WMM fraction |
| DNPEP | SUCLG1 | 0.012 | 0.15 | fraction |
| FAH | SUCLG1 | 0.01 | 0.121 | fraction |
| SARS | SUCLG1 | 0.007 | 0.002 | bioplex_WMM WMM_only |
| PGD | DNPEP | 0.007 | 0.004 | fraction |
| PGM2 | SARS | 0.007 | 0.004 | bioplex_WMM WMM_only |
| PGD | SUCLG1 | 0.0 | 0.008 | bioplex_WMM fraction |
| TXNDC17 | FAH | 0.0 | 0.001 | bioplex_WMM fraction |
| TXNDC17 | DNPEP | 0.0 | 0.001 | fraction |
Images
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Complex HuMAP2_02703 has an average edge precision of 0.313 which is ranked 4427 out of all 6965 complexes.
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