hu.MAP 2.0: Complex View
Human Protein Complex Map
Search for a protein
Complex: HuMAP2_02712
Confidence: Medium
Proteins| Genename | Protein Name | Links |
|---|---|---|
| DSCC1 | Sister chromatid cohesion protein DCC1 (Defective in sister chromatid cohesion protein 1 homolog) | UniProt NCBI |
| ATAD5 | ATPase family AAA domain-containing protein 5 (Chromosome fragility-associated gene 1 protein) | UniProt NCBI |
| RAD17 | Cell cycle checkpoint protein RAD17 (hRad17) (RF-C/activator 1 homolog) | UniProt NCBI |
| CHTF8 | Chromosome transmission fidelity protein 8 homolog (hCTF8) | UniProt NCBI |
| RFC2 | Replication factor C subunit 2 (Activator 1 40 kDa subunit) (A1 40 kDa subunit) (Activator 1 subunit 2) (Replication factor C 40 kDa subunit) (RF-C 40 kDa subunit) (RFC40) | UniProt NCBI |
| RFC3 | Replication factor C subunit 3 (Activator 1 38 kDa subunit) (A1 38 kDa subunit) (Activator 1 subunit 3) (Replication factor C 38 kDa subunit) (RF-C 38 kDa subunit) (RFC38) | UniProt NCBI |
| RFC4 | Replication factor C subunit 4 (Activator 1 37 kDa subunit) (A1 37 kDa subunit) (Activator 1 subunit 4) (Replication factor C 37 kDa subunit) (RF-C 37 kDa subunit) (RFC37) | UniProt NCBI |
| RFC5 | Replication factor C subunit 5 (Activator 1 36 kDa subunit) (A1 36 kDa subunit) (Activator 1 subunit 5) (Replication factor C 36 kDa subunit) (RF-C 36 kDa subunit) (RFC36) | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| GO:0003689 | 9.93317232561e-20 | 0.875 | CHTF8 RFC5 DSCC1 RFC2 RFC4 RFC3 RAD17 | DNA clamp loader activity |
| GO:0033170 | 9.93317232561e-20 | 0.875 | CHTF8 RFC5 DSCC1 RFC2 RFC4 RFC3 RAD17 | protein-DNA loading ATPase activity |
| CORUM:2804 | 5.99037691178e-19 | 0.75 | CHTF8 RFC5 DSCC1 RFC2 RFC4 RFC3 | CTF18-cohesion-RFC complex |
| CORUM:3070 | 2.39587484326e-18 | 0.75 | CHTF8 RFC5 DSCC1 RFC2 RFC4 RFC3 | CTF18-cohesion-RFC-POLH complex |
| CORUM:266 | 4.24766632997e-16 | 0.625 | RFC5 RFC4 RFC2 RAD17 RFC3 | RAD17-RFC complex |
| CORUM:270 | 4.24766632997e-16 | 0.625 | RFC5 RFC4 RFC2 RAD17 RFC3 | RAD17-RFC complex |
| CORUM:2810 | 4.24766632997e-16 | 0.625 | RFC5 RFC4 RFC2 RAD17 RFC3 | RAD17-RFC complex |
| GO:1900262 | 6.46960706472e-16 | 0.75 | CHTF8 RFC5 DSCC1 RFC2 RFC4 RFC3 | regulation of DNA-directed DNA polymerase activity |
| GO:1900264 | 6.46960706472e-16 | 0.75 | CHTF8 RFC5 DSCC1 RFC2 RFC4 RFC3 | positive regulation of DNA-directed DNA polymerase activity |
| GO:0031390 | 2.58754483072e-15 | 0.75 | CHTF8 RFC5 DSCC1 RFC2 RFC4 RFC3 | Ctf18 RFC-like complex |
| GO:0006275 | 1.95569626582e-14 | 1.0 | CHTF8 RFC5 DSCC1 RFC2 RFC4 RFC3 RAD17 ATAD5 | regulation of DNA replication |
| CORUM:268 | 2.3774950694e-14 | 0.625 | RFC5 RFC4 RFC2 RAD17 RFC3 | 9-1-1-RAD17-RFC complex |
| CORUM:274 | 2.3774950694e-14 | 0.625 | RFC5 RFC4 RFC2 RAD17 RFC3 | 9-1-1-RAD17-RFC complex |
| GO:0017116 | 1.14250973879e-12 | 0.75 | CHTF8 RFC5 DSCC1 RFC2 RFC4 RFC3 | single-stranded DNA helicase activity |
| CORUM:2200 | 1.58119379133e-12 | 0.5 | RFC5 RFC4 RFC2 RFC3 | RFC2-5 subcomplex |
| CORUM:279 | 7.90426989013e-12 | 0.5 | RFC5 RFC4 RFC2 RFC3 | RFC complex |
| CORUM:2199 | 7.90426989013e-12 | 0.5 | RFC5 RFC4 RFC2 RFC3 | CHTF18-RFC2-5 complex |
| CORUM:2201 | 7.90426989013e-12 | 0.5 | RFC5 RFC4 RFC2 RFC3 | PCNA-RFC2-5 complex |
| CORUM:2202 | 7.90426989013e-12 | 0.5 | RFC5 RFC4 RFC2 RFC3 | CHTF18-RFC2-5 complex |
| CORUM:2799 | 7.90426989013e-12 | 0.5 | RFC5 RFC4 RFC2 RFC3 | RFC complex |
| CORUM:277 | 7.90426989013e-12 | 0.5 | RFC5 RFC4 RFC2 RFC3 | RFC complex |
| CORUM:2203 | 2.37077133267e-11 | 0.5 | RFC5 RFC4 RFC2 RFC3 | BRD4-RFC complex |
| CORUM:2797 | 2.37077133267e-11 | 0.5 | RFC5 RFC4 RFC2 RFC3 | PCNA-CHL12-RFC2-5 complex |
| GO:0006260 | 6.3244708037e-11 | 1.0 | CHTF8 RFC5 DSCC1 RFC2 RFC4 RFC3 RAD17 ATAD5 | DNA replication |
| GO:0042623 | 7.1060582536e-11 | 1.0 | CHTF8 RFC5 DSCC1 RFC2 RFC4 RFC3 RAD17 ATAD5 | ATPase activity, coupled |
| GO:0008094 | 1.0823804141e-10 | 0.875 | CHTF8 RFC5 DSCC1 RFC2 RFC4 RFC3 RAD17 | DNA-dependent ATPase activity |
| CORUM:1003 | 1.99016407209e-10 | 0.5 | RFC5 RFC4 RFC2 RFC3 | RC complex (Replication competent complex) |
| GO:0090329 | 3.00431142893e-10 | 0.75 | CHTF8 RFC5 DSCC1 RFC2 RFC4 RFC3 | regulation of DNA-dependent DNA replication |
| REAC:R-HSA-5685938 | 6.10090989714e-10 | 0.625 | RFC5 RFC4 RFC2 RAD17 RFC3 | HDR through Single Strand Annealing (SSA) |
| REAC:R-HSA-176187 | 7.05299066681e-10 | 0.625 | RFC5 RFC4 RFC2 RAD17 RFC3 | Activation of ATR in response to replication stress |
| REAC:R-HSA-5693616 | 8.12025961431e-10 | 0.625 | RFC5 RFC4 RFC2 RAD17 RFC3 | Presynaptic phase of homologous DNA pairing and strand exchange |
| REAC:R-HSA-5693579 | 1.21174079583e-09 | 0.625 | RFC5 RFC4 RFC2 RAD17 RFC3 | Homologous DNA Pairing and Strand Exchange |
| GO:0016887 | 1.78687442063e-09 | 1.0 | CHTF8 RFC5 DSCC1 RFC2 RFC4 RFC3 RAD17 ATAD5 | ATPase activity |
| GO:0003678 | 3.33458518048e-09 | 0.75 | CHTF8 RFC5 DSCC1 RFC2 RFC4 RFC3 | DNA helicase activity |
| GO:2000573 | 3.33458518048e-09 | 0.75 | CHTF8 RFC5 DSCC1 RFC2 RFC4 RFC3 | positive regulation of DNA biosynthetic process |
| CORUM:278 | 4.70911134935e-09 | 0.375 | RFC4 RFC2 RFC5 | RFC core complex |
| REAC:R-HSA-174411 | 6.04867413181e-09 | 0.5 | RFC5 RFC4 RFC2 RFC3 | Polymerase switching on the C-strand of the telomere |
| REAC:R-HSA-69091 | 6.04867413181e-09 | 0.5 | RFC5 RFC4 RFC2 RFC3 | Polymerase switching |
| REAC:R-HSA-69109 | 6.04867413181e-09 | 0.5 | RFC5 RFC4 RFC2 RFC3 | Leading Strand Synthesis |
| GO:0005663 | 8.53661148134e-09 | 0.5 | RFC5 RFC4 RFC2 RFC3 | DNA replication factor C complex |
| REAC:R-HSA-110312 | 1.09928605357e-08 | 0.5 | RFC5 RFC4 RFC2 RFC3 | Translesion synthesis by REV1 |
| REAC:R-HSA-5685942 | 1.33019920702e-08 | 0.625 | RFC5 RFC4 RFC2 RAD17 RFC3 | HDR through Homologous Recombination (HRR) |
| REAC:R-HSA-5655862 | 1.43721880369e-08 | 0.5 | RFC5 RFC4 RFC2 RFC3 | Translesion synthesis by POLK |
| REAC:R-HSA-5656121 | 1.43721880369e-08 | 0.5 | RFC5 RFC4 RFC2 RFC3 | Translesion synthesis by POLI |
| KEGG:03430 | 1.44807079915e-08 | 0.5 | RFC5 RFC4 RFC2 RFC3 | Mismatch repair |
| CORUM:613 | 1.8831701816e-08 | 0.375 | DSCC1 RFC3 CHTF8 | CTF18-CTF8-DCC1-RFC3 complex |
| REAC:R-HSA-110320 | 2.33960691039e-08 | 0.5 | RFC5 RFC4 RFC2 RFC3 | Translesion Synthesis by POLH |
| WP:WP2363 | 2.57180787826e-08 | 0.5 | RAD17 DSCC1 RFC3 RFC4 | Gastric Cancer Network 2 |
| REAC:R-HSA-69186 | 2.92387969037e-08 | 0.5 | RFC5 RFC4 RFC2 RFC3 | Lagging Strand Synthesis |
| REAC:R-HSA-5651801 | 3.61107457747e-08 | 0.5 | RFC5 RFC4 RFC2 RFC3 | PCNA-Dependent Long Patch Base Excision Repair |
| GO:2000278 | 4.96208104538e-08 | 0.75 | CHTF8 RFC5 DSCC1 RFC2 RFC4 RFC3 | regulation of DNA biosynthetic process |
| GO:0004386 | 5.6995229111e-08 | 0.75 | CHTF8 RFC5 DSCC1 RFC2 RFC4 RFC3 | helicase activity |
| REAC:R-HSA-174417 | 6.40710506278e-08 | 0.5 | RFC5 RFC4 RFC2 RFC3 | Telomere C-strand (Lagging Strand) Synthesis |
| REAC:R-HSA-6804756 | 7.45647730076e-08 | 0.625 | RFC5 RFC4 RFC2 RAD17 RFC3 | Regulation of TP53 Activity through Phosphorylation |
| REAC:R-HSA-110373 | 7.62586526259e-08 | 0.5 | RFC5 RFC4 RFC2 RFC3 | Resolution of AP sites via the multiple-nucleotide patch replacement pathway |
| REAC:R-HSA-5696397 | 7.62586526259e-08 | 0.5 | RFC5 RFC4 RFC2 RFC3 | Gap-filling DNA repair synthesis and ligation in GG-NER |
| REAC:R-HSA-69473 | 8.79671668475e-08 | 0.625 | RFC5 RFC4 RFC2 RAD17 RFC3 | G2/M DNA damage checkpoint |
| KEGG:03030 | 9.60590951861e-08 | 0.5 | RFC5 RFC4 RFC2 RFC3 | DNA replication |
| REAC:R-HSA-5693607 | 1.03227550056e-07 | 0.625 | RFC5 RFC4 RFC2 RAD17 RFC3 | Processing of DNA double-strand break ends |
| REAC:R-HSA-110314 | 1.65029347917e-07 | 0.5 | RFC5 RFC4 RFC2 RFC3 | Recognition of DNA damage by PCNA-containing replication complex |
| REAC:R-HSA-180786 | 1.65029347917e-07 | 0.5 | RFC5 RFC4 RFC2 RFC3 | Extension of Telomeres |
| REAC:R-HSA-5656169 | 1.89437369763e-07 | 0.5 | RFC5 RFC4 RFC2 RFC3 | Termination of translesion DNA synthesis |
| WP:WP466 | 1.91888194403e-07 | 0.5 | RFC5 RFC4 RFC2 RFC3 | DNA Replication |
| REAC:R-HSA-69190 | 2.16453264205e-07 | 0.5 | RFC5 RFC4 RFC2 RFC3 | DNA strand elongation |
| KEGG:03420 | 2.20994450988e-07 | 0.5 | RFC5 RFC4 RFC2 RFC3 | Nucleotide excision repair |
| GO:0017111 | 2.38710707286e-07 | 1.0 | CHTF8 RFC5 DSCC1 RFC2 RFC4 RFC3 RAD17 ATAD5 | nucleoside-triphosphatase activity |
| REAC:R-HSA-73933 | 3.14966003786e-07 | 0.5 | RFC5 RFC4 RFC2 RFC3 | Resolution of Abasic Sites (AP sites) |
| GO:0016462 | 4.09751197638e-07 | 1.0 | CHTF8 RFC5 DSCC1 RFC2 RFC4 RFC3 RAD17 ATAD5 | pyrophosphatase activity |
| GO:0016817 | 4.20578185594e-07 | 1.0 | CHTF8 RFC5 DSCC1 RFC2 RFC4 RFC3 RAD17 ATAD5 | hydrolase activity, acting on acid anhydrides |
| GO:0016818 | 4.20578185594e-07 | 1.0 | CHTF8 RFC5 DSCC1 RFC2 RFC4 RFC3 RAD17 ATAD5 | hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides |
| REAC:R-HSA-110313 | 4.43739625768e-07 | 0.5 | RFC5 RFC4 RFC2 RFC3 | Translesion synthesis by Y family DNA polymerases bypasses lesions on DNA template |
| REAC:R-HSA-5693567 | 4.55947799744e-07 | 0.625 | RFC5 RFC4 RFC2 RAD17 RFC3 | HDR through Homologous Recombination (HRR) or Single Strand Annealing (SSA) |
| GO:0006261 | 4.71190498317e-07 | 0.75 | CHTF8 RFC5 DSCC1 RFC2 RFC4 RFC3 | DNA-dependent DNA replication |
| REAC:R-HSA-5693538 | 5.72743727546e-07 | 0.625 | RFC5 RFC4 RFC2 RAD17 RFC3 | Homology Directed Repair |
| REAC:R-HSA-5696400 | 6.08392575302e-07 | 0.5 | RFC5 RFC4 RFC2 RFC3 | Dual Incision in GG-NER |
| GO:0071897 | 9.71594478232e-07 | 0.75 | CHTF8 RFC5 DSCC1 RFC2 RFC4 RFC3 | DNA biosynthetic process |
| REAC:R-HSA-73893 | 1.07016718079e-06 | 0.5 | RFC5 RFC4 RFC2 RFC3 | DNA Damage Bypass |
| REAC:R-HSA-5633007 | 1.18190461448e-06 | 0.625 | RFC5 RFC4 RFC2 RAD17 RFC3 | Regulation of TP53 Activity |
| GO:0051054 | 1.40877955049e-06 | 0.75 | CHTF8 RFC5 DSCC1 RFC2 RFC4 RFC3 | positive regulation of DNA metabolic process |
| REAC:R-HSA-5693532 | 1.47228520714e-06 | 0.625 | RFC5 RFC4 RFC2 RAD17 RFC3 | DNA Double-Strand Break Repair |
| REAC:R-HSA-69481 | 1.61294267391e-06 | 0.625 | RFC5 RFC4 RFC2 RAD17 RFC3 | G2/M Checkpoints |
| GO:0140097 | 3.31598308806e-06 | 0.75 | CHTF8 RFC5 DSCC1 RFC2 RFC4 RFC3 | catalytic activity, acting on DNA |
| REAC:R-HSA-6782210 | 3.79823767099e-06 | 0.5 | RFC5 RFC4 RFC2 RFC3 | Gap-filling DNA repair synthesis and ligation in TC-NER |
| REAC:R-HSA-6782135 | 4.04643017452e-06 | 0.5 | RFC5 RFC4 RFC2 RFC3 | Dual incision in TC-NER |
| GO:0070987 | 8.24534072683e-06 | 0.5 | RFC5 RFC4 RFC2 RFC3 | error-free translesion synthesis |
| GO:0042276 | 8.24534072683e-06 | 0.5 | RFC5 RFC4 RFC2 RFC3 | error-prone translesion synthesis |
| REAC:R-HSA-6781827 | 8.50137867262e-06 | 0.5 | RFC5 RFC4 RFC2 RFC3 | Transcription-Coupled Nucleotide Excision Repair (TC-NER) |
| REAC:R-HSA-157579 | 9.90934286775e-06 | 0.5 | RFC5 RFC4 RFC2 RFC3 | Telomere Maintenance |
| REAC:R-HSA-5696399 | 1.14847975382e-05 | 0.5 | RFC5 RFC4 RFC2 RFC3 | Global Genome Nucleotide Excision Repair (GG-NER) |
| CORUM:2805 | 1.16880143691e-05 | 0.25 | DSCC1 CHTF8 | CTF8-DCC1 subcomplex |
| REAC:R-HSA-73884 | 1.32404244641e-05 | 0.5 | RFC5 RFC4 RFC2 RFC3 | Base Excision Repair |
| GO:0006297 | 1.50599363112e-05 | 0.5 | RFC5 RFC4 RFC2 RFC3 | nucleotide-excision repair, DNA gap filling |
| REAC:R-HSA-69620 | 2.43008641553e-05 | 0.625 | RFC5 RFC4 RFC2 RAD17 RFC3 | Cell Cycle Checkpoints |
| GO:0032201 | 2.98220816207e-05 | 0.5 | RFC5 RFC4 RFC2 RFC3 | telomere maintenance via semi-conservative replication |
| REAC:R-HSA-73886 | 3.17336382382e-05 | 0.5 | RFC5 RFC4 RFC2 RFC3 | Chromosome Maintenance |
| REAC:R-HSA-5696398 | 3.41708889161e-05 | 0.5 | RFC5 RFC4 RFC2 RFC3 | Nucleotide Excision Repair |
| CORUM:612 | 3.50546248845e-05 | 0.25 | DSCC1 CHTF8 | CTF18-CTF8-DCC1 complex |
| CORUM:2806 | 3.50546248845e-05 | 0.25 | DSCC1 CHTF8 | CTF18-CTF8-DCC1 complex |
| GO:0051052 | 3.89351242067e-05 | 0.75 | CHTF8 RFC5 DSCC1 RFC2 RFC4 RFC3 | regulation of DNA metabolic process |
| REAC:R-HSA-73894 | 4.24460256581e-05 | 0.625 | RFC5 RFC4 RFC2 RAD17 RFC3 | DNA Repair |
| REAC:R-HSA-69239 | 4.53422061837e-05 | 0.5 | RFC5 RFC4 RFC2 RFC3 | Synthesis of DNA |
| REAC:R-HSA-69306 | 5.9038512788e-05 | 0.5 | RFC5 RFC4 RFC2 RFC3 | DNA Replication |
| REAC:R-HSA-3700989 | 6.34254423851e-05 | 0.625 | RFC5 RFC4 RFC2 RAD17 RFC3 | Transcriptional Regulation by TP53 |
| GO:0042769 | 9.99014589936e-05 | 0.5 | RFC5 RFC4 RFC2 RFC3 | DNA damage response, detection of DNA damage |
| GO:0044427 | 0.000101191516069 | 1.0 | CHTF8 RFC5 DSCC1 RFC2 RFC4 RFC3 RAD17 ATAD5 | chromosomal part |
| GO:0006296 | 0.000111986618346 | 0.5 | RFC5 RFC4 RFC2 RFC3 | nucleotide-excision repair, DNA incision, 5'-to lesion |
| GO:0003677 | 0.000131001245107 | 1.0 | CHTF8 RFC5 DSCC1 RFC2 RFC4 RFC3 RAD17 ATAD5 | DNA binding |
| GO:0005694 | 0.00013521994769 | 1.0 | CHTF8 RFC5 DSCC1 RFC2 RFC4 RFC3 RAD17 ATAD5 | chromosome |
| GO:0033683 | 0.00013940565471 | 0.5 | RFC5 RFC4 RFC2 RFC3 | nucleotide-excision repair, DNA incision |
| REAC:R-HSA-69242 | 0.000150143341926 | 0.5 | RFC5 RFC4 RFC2 RFC3 | S Phase |
| GO:0019985 | 0.000154861828642 | 0.5 | RFC5 RFC4 RFC2 RFC3 | translesion synthesis |
| CORUM:435 | 0.000175131922226 | 0.25 | RFC4 RFC2 | BASC (Ab 81) complex (BRCA1-associated genome surveillance complex) |
| GO:0006259 | 0.000210601211554 | 0.875 | CHTF8 RFC5 DSCC1 RFC2 RFC4 RFC3 RAD17 | DNA metabolic process |
| GO:0000731 | 0.000276162599924 | 0.5 | RFC5 RFC4 RFC2 RFC3 | DNA synthesis involved in DNA repair |
| CORUM:434 | 0.000326737313819 | 0.25 | RFC4 RFC2 | BASC (Ab 80) complex (BRCA1-associated genome surveillance complex) |
| GO:1901796 | 0.000378328505435 | 0.625 | RFC5 RFC4 RFC2 RAD17 RFC3 | regulation of signal transduction by p53 class mediator |
| GO:0006301 | 0.00038940760077 | 0.5 | RFC5 RFC4 RFC2 RFC3 | postreplication repair |
| GO:0033260 | 0.000457563898772 | 0.5 | RFC5 RFC4 RFC2 RFC3 | nuclear DNA replication |
| WP:WP2446 | 0.000534181644969 | 0.375 | RFC4 RFC3 RFC5 | Retinoblastoma Gene in Cancer |
| GO:0044786 | 0.000620237823973 | 0.5 | RFC5 RFC4 RFC2 RFC3 | cell cycle DNA replication |
| CORUM:433 | 0.000769339286093 | 0.25 | RFC4 RFC2 | BASC complex (BRCA1-associated genome surveillance complex) |
| GO:0051347 | 0.000978927120993 | 0.75 | CHTF8 RFC5 DSCC1 RFC2 RFC4 RFC3 | positive regulation of transferase activity |
| GO:0005657 | 0.00107110302322 | 0.5 | RFC5 RFC4 RFC2 RFC3 | replication fork |
| REAC:R-HSA-1640170 | 0.00108292913925 | 0.625 | RFC5 RFC4 RFC2 RAD17 RFC3 | Cell Cycle |
| GO:0006283 | 0.00183129501431 | 0.5 | RFC5 RFC4 RFC2 RFC3 | transcription-coupled nucleotide-excision repair |
| GO:0016787 | 0.00203376575868 | 1.0 | CHTF8 RFC5 DSCC1 RFC2 RFC4 RFC3 RAD17 ATAD5 | hydrolase activity |
| GO:0072331 | 0.0023171202017 | 0.625 | RFC5 RFC4 RFC2 RAD17 RFC3 | signal transduction by p53 class mediator |
| GO:0022402 | 0.0042701794658 | 0.875 | RFC5 DSCC1 RFC2 RFC4 RFC3 RAD17 ATAD5 | cell cycle process |
| GO:0006289 | 0.0079874415284 | 0.5 | RFC5 RFC4 RFC2 RFC3 | nucleotide-excision repair |
| CORUM:0000000 | 0.00993810898821 | 0.875 | CHTF8 RFC5 DSCC1 RFC2 RFC4 RFC3 RAD17 | CORUM root |
| GO:0051338 | 0.010227554511 | 0.75 | CHTF8 RFC5 DSCC1 RFC2 RFC4 RFC3 | regulation of transferase activity |
| GO:0010557 | 0.01150474629 | 0.875 | CHTF8 RFC5 DSCC1 RFC2 RFC4 RFC3 ATAD5 | positive regulation of macromolecule biosynthetic process |
| REAC:R-HSA-212436 | 0.0132859010078 | 0.625 | RFC5 RFC4 RFC2 RAD17 RFC3 | Generic Transcription Pathway |
| GO:0007049 | 0.0140553715629 | 0.875 | RFC5 DSCC1 RFC2 RFC4 RFC3 RAD17 ATAD5 | cell cycle |
| GO:0031328 | 0.0153801389192 | 0.875 | CHTF8 RFC5 DSCC1 RFC2 RFC4 RFC3 ATAD5 | positive regulation of cellular biosynthetic process |
| REAC:R-HSA-69278 | 0.0158165770804 | 0.5 | RFC5 RFC4 RFC2 RFC3 | Cell Cycle, Mitotic |
| GO:0009891 | 0.0168100413109 | 0.875 | CHTF8 RFC5 DSCC1 RFC2 RFC4 RFC3 ATAD5 | positive regulation of biosynthetic process |
| GO:0090305 | 0.0177371420122 | 0.5 | RFC5 RFC4 RFC2 RFC3 | nucleic acid phosphodiester bond hydrolysis |
| REAC:R-HSA-73857 | 0.0224473446481 | 0.625 | RFC5 RFC4 RFC2 RAD17 RFC3 | RNA Polymerase II Transcription |
| GO:2000112 | 0.0246985668667 | 1.0 | CHTF8 RFC5 DSCC1 RFC2 RFC4 RFC3 RAD17 ATAD5 | regulation of cellular macromolecule biosynthetic process |
| GO:0010556 | 0.028892472479 | 1.0 | CHTF8 RFC5 DSCC1 RFC2 RFC4 RFC3 RAD17 ATAD5 | regulation of macromolecule biosynthetic process |
| GO:0000723 | 0.0335258158335 | 0.5 | RFC5 RFC4 RFC2 RFC3 | telomere maintenance |
| GO:0003676 | 0.0339112472963 | 1.0 | CHTF8 RFC5 DSCC1 RFC2 RFC4 RFC3 RAD17 ATAD5 | nucleic acid binding |
| GO:0051606 | 0.0362947680097 | 0.5 | RFC5 RFC4 RFC2 RFC3 | detection of stimulus |
| GO:0043085 | 0.03767041438 | 0.75 | CHTF8 RFC5 DSCC1 RFC2 RFC4 RFC3 | positive regulation of catalytic activity |
| GO:0031391 | 0.0378589948753 | 0.25 | RFC4 ATAD5 | Elg1 RFC-like complex |
| REAC:R-HSA-74160 | 0.037866398773 | 0.625 | RFC5 RFC4 RFC2 RAD17 RFC3 | Gene expression (Transcription) |
| GO:0031326 | 0.038100921268 | 1.0 | CHTF8 RFC5 DSCC1 RFC2 RFC4 RFC3 RAD17 ATAD5 | regulation of cellular biosynthetic process |
| GO:0009889 | 0.044342603266 | 1.0 | CHTF8 RFC5 DSCC1 RFC2 RFC4 RFC3 RAD17 ATAD5 | regulation of biosynthetic process |
| GO:0032200 | 0.0467680285702 | 0.5 | RFC5 RFC4 RFC2 RFC3 | telomere organization |
| CORUM:1132 | 0.0497224828424 | 0.125 | RFC4 | RFC2-RIalpha complex |
| CORUM:1131 | 0.0497224828424 | 0.125 | RFC2 | RFC2-RIalpha complex |
Edges
| Protein 1 | Protein 2 | Score | Precision | Evidence |
|---|---|---|---|---|
| RFC3 | RFC5 | 1.0 | 0.949 | hein_WMM bioplex (RFC5) bioplex_WMM Guru youn_WMM Malo fraction treiber_WMM |
| RFC2 | RFC4 | 1.0 | 0.949 | hein_WMM bioplex (RFC4) bioplex_WMM Guru youn_WMM Malo gupta_WMM fraction boldt_WMM treiber_WMM |
| RFC5 | RFC4 | 1.0 | 0.949 | hein_WMM bioplex (RFC4,RFC5) bioplex_WMM Guru youn_WMM Malo gupta_WMM fraction treiber_WMM |
| RFC3 | RFC4 | 1.0 | 0.949 | hein_WMM bioplex (RFC4) bioplex_WMM Guru boldt youn_WMM Malo gupta_WMM fraction boldt_WMM treiber_WMM |
| RFC2 | RFC3 | 1.0 | 0.949 | hein_WMM bioplex_WMM Guru youn_WMM Malo gupta_WMM fraction boldt_WMM treiber_WMM |
| RFC2 | RFC5 | 0.999 | 0.948 | hein_WMM bioplex (RFC5) bioplex_WMM Guru youn_WMM Malo fraction treiber_WMM |
| DSCC1 | CHTF8 | 0.991 | 0.91 | bioplex (DSCC1) bioplex_WMM |
| RFC4 | ATAD5 | 0.894 | 0.819 | hein_WMM bioplex (RFC4) bioplex_WMM youn_WMM gupta_WMM |
| DSCC1 | RFC4 | 0.846 | 0.789 | bioplex (DSCC1,RFC4) bioplex_WMM |
| RFC5 | DSCC1 | 0.582 | 0.663 | bioplex (DSCC1,RFC5) bioplex_WMM |
| RFC3 | DSCC1 | 0.452 | 0.595 | bioplex (DSCC1) bioplex_WMM |
| RFC2 | DSCC1 | 0.444 | 0.588 | bioplex (DSCC1) bioplex_WMM |
| RFC4 | RAD17 | 0.239 | 0.47 | bioplex (RAD17,RFC4) bioplex_WMM youn_WMM |
| RFC4 | CHTF8 | 0.134 | 0.405 | bioplex (RFC4) bioplex_WMM |
| RFC5 | ATAD5 | 0.133 | 0.406 | hein_WMM bioplex (RFC5) bioplex_WMM youn_WMM |
| RFC5 | RAD17 | 0.059 | 0.328 | bioplex (RAD17,RFC5) bioplex_WMM youn_WMM |
| RFC5 | CHTF8 | 0.049 | 0.294 | bioplex (RFC5) bioplex_WMM |
| RFC3 | RAD17 | 0.014 | 0.137 | bioplex (RAD17) bioplex_WMM youn_WMM |
| RFC2 | RAD17 | 0.012 | 0.148 | bioplex (RAD17) bioplex_WMM |
| RFC2 | ATAD5 | 0.011 | 0.144 | hein_WMM bioplex_WMM youn_WMM WMM_only |
| RFC2 | CHTF8 | 0.011 | 0.146 | bioplex_WMM WMM_only |
| ATAD5 | RAD17 | 0.01 | 0.107 | bioplex_WMM WMM_only |
| ATAD5 | CHTF8 | 0.009 | 0.112 | bioplex_WMM WMM_only |
| DSCC1 | ATAD5 | 0.009 | 0.104 | bioplex_WMM WMM_only |
| RAD17 | CHTF8 | 0.009 | 0.097 | bioplex_WMM WMM_only |
| DSCC1 | RAD17 | 0.009 | 0.097 | bioplex_WMM WMM_only |
| RFC3 | CHTF8 | 0.008 | 0.083 | bioplex_WMM WMM_only |
| RFC3 | ATAD5 | 0.003 | 0.009 | hein_WMM bioplex_WMM youn_WMM fraction |
Images
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Complex HuMAP2_02712 has an average edge precision of 0.469 which is ranked 2706 out of all 6965 complexes.
Related Complexes
| Genename | Complexes |
|---|---|
| DSCC1 | HuMAP2_00874 HuMAP2_01694 HuMAP2_02712 |
| ATAD5 | HuMAP2_00874 HuMAP2_02712 HuMAP2_02847 HuMAP2_05133 |
| RAD17 | HuMAP2_00874 HuMAP2_02712 |
| CHTF8 | HuMAP2_00874 HuMAP2_01694 HuMAP2_02712 HuMAP2_02959 |
| RFC2 | HuMAP2_00430 HuMAP2_00874 HuMAP2_02712 HuMAP2_02847 |
| RFC3 | HuMAP2_00430 HuMAP2_00874 HuMAP2_02712 HuMAP2_02847 |
| RFC4 | HuMAP2_00874 HuMAP2_02712 HuMAP2_02847 HuMAP2_05133 |
| RFC5 | HuMAP2_00430 HuMAP2_00874 HuMAP2_02712 HuMAP2_02847 |