hu.MAP 2.0: Complex View
Human Protein Complex Map
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Complex: HuMAP2_02728
Confidence: Medium High
Proteins| Genename | Protein Name | Links |
|---|---|---|
| NUP42 | Nucleoporin-like protein 2 (NLP-1) (NUP42 homolog) (Nucleoporin hCG1) | UniProt NCBI |
| NXF1 | Nuclear RNA export factor 1 (Tip-associated protein) (Tip-associating protein) (mRNA export factor TAP) | UniProt NCBI |
| GLE1 | Nucleoporin GLE1 (hGLE1) (GLE1-like protein) | UniProt NCBI |
| NXT1 | NTF2-related export protein 1 (Protein p15) | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| REAC:R-HSA-159236 | 7.38564283704e-08 | 1.0 | GLE1 NXT1 NXF1 NUP42 | Transport of Mature mRNA derived from an Intron-Containing Transcript |
| REAC:R-HSA-72202 | 1.22728265013e-07 | 1.0 | GLE1 NXT1 NXF1 NUP42 | Transport of Mature Transcript to Cytoplasm |
| REAC:R-HSA-72203 | 1.12324610099e-05 | 1.0 | GLE1 NXT1 NXF1 NUP42 | Processing of Capped Intron-Containing Pre-mRNA |
| CORUM:1348 | 1.50819606993e-05 | 0.5 | NUP42 GLE1 | GLE1-NUPL2-NUP155 complex |
| GO:0006406 | 0.000125895977869 | 1.0 | GLE1 NXT1 NXF1 NUP42 | mRNA export from nucleus |
| GO:0071427 | 0.000125895977869 | 1.0 | GLE1 NXT1 NXF1 NUP42 | mRNA-containing ribonucleoprotein complex export from nucleus |
| GO:0051028 | 0.000151516440356 | 1.0 | GLE1 NXT1 NXF1 NUP42 | mRNA transport |
| KEGG:03013 | 0.000156303289806 | 0.75 | NXT1 NXF1 NUP42 | RNA transport |
| GO:0071426 | 0.000214275729623 | 1.0 | GLE1 NXT1 NXF1 NUP42 | ribonucleoprotein complex export from nucleus |
| GO:0071166 | 0.000221478275157 | 1.0 | GLE1 NXT1 NXF1 NUP42 | ribonucleoprotein complex localization |
| GO:0006405 | 0.000285834009959 | 1.0 | GLE1 NXT1 NXF1 NUP42 | RNA export from nucleus |
| GO:0050657 | 0.000494260781771 | 1.0 | GLE1 NXT1 NXF1 NUP42 | nucleic acid transport |
| GO:0050658 | 0.000494260781771 | 1.0 | GLE1 NXT1 NXF1 NUP42 | RNA transport |
| GO:0051236 | 0.000535430121219 | 1.0 | GLE1 NXT1 NXF1 NUP42 | establishment of RNA localization |
| GO:0006611 | 0.000609694967109 | 1.0 | GLE1 NXT1 NXF1 NUP42 | protein export from nucleus |
| REAC:R-HSA-8953854 | 0.000676603019954 | 1.0 | GLE1 NXT1 NXF1 NUP42 | Metabolism of RNA |
| GO:0051168 | 0.000819333954364 | 1.0 | GLE1 NXT1 NXF1 NUP42 | nuclear export |
| GO:0015931 | 0.000879263724448 | 1.0 | GLE1 NXT1 NXF1 NUP42 | nucleobase-containing compound transport |
| GO:0006403 | 0.00117775012637 | 1.0 | GLE1 NXT1 NXF1 NUP42 | RNA localization |
| GO:0031503 | 0.00272272763799 | 1.0 | GLE1 NXT1 NXF1 NUP42 | protein-containing complex localization |
| REAC:R-HSA-159227 | 0.00436320194063 | 0.5 | NXF1 NUP42 | Transport of the SLBP independent Mature mRNA |
| REAC:R-HSA-159230 | 0.00466369436644 | 0.5 | NXF1 NUP42 | Transport of the SLBP Dependant Mature mRNA |
| GO:0006913 | 0.00512711596139 | 1.0 | GLE1 NXT1 NXF1 NUP42 | nucleocytoplasmic transport |
| GO:0051169 | 0.0053619122614 | 1.0 | GLE1 NXT1 NXF1 NUP42 | nuclear transport |
| KEGG:03008 | 0.00582341320088 | 0.5 | NXT1 NXF1 | Ribosome biogenesis in eukaryotes |
| REAC:R-HSA-159231 | 0.00667602194349 | 0.5 | NXF1 NUP42 | Transport of Mature mRNA Derived from an Intronless Transcript |
| REAC:R-HSA-159234 | 0.0070462802506 | 0.5 | NXF1 NUP42 | Transport of Mature mRNAs Derived from Intronless Transcripts |
| KEGG:03015 | 0.00761107721317 | 0.5 | NXT1 NXF1 | mRNA surveillance pathway |
| KEGG:05164 | 0.0215119370249 | 0.5 | NXT1 NXF1 | Influenza A |
Edges
| Protein 1 | Protein 2 | Score | Precision | Evidence |
|---|---|---|---|---|
| NXF1 | NXT1 | 0.948 | 0.856 | hein_WMM youn (NXF1) bioplex (NXF1) bioplex_WMM Guru youn_WMM fraction |
| NUP42 | GLE1 | 0.352 | 0.538 | hein_WMM youn (GLE1) bioplex_WMM youn_WMM |
| NXF1 | GLE1 | 0.249 | 0.472 | hein_WMM youn (GLE1,NXF1) bioplex (NXF1) bioplex_WMM youn_WMM |
| NXF1 | NUP42 | 0.102 | 0.366 | hein_WMM youn (NXF1) bioplex (NXF1) bioplex_WMM youn_WMM gupta_WMM |
| NXT1 | GLE1 | 0.01 | 0.131 | hein_WMM youn (GLE1) bioplex_WMM youn_WMM |
| NUP42 | NXT1 | 0.01 | 0.105 | hein_WMM bioplex_WMM youn_WMM WMM_only |
Images
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Complex HuMAP2_02728 has an average edge precision of 0.411 which is ranked 3183 out of all 6965 complexes.
Related Complexes
| Genename | Complexes |
|---|---|
| NUP42 | HuMAP2_02728 HuMAP2_04845 HuMAP2_04881 |
| NXF1 | HuMAP2_02388 HuMAP2_02728 HuMAP2_04845 HuMAP2_05527 |
| GLE1 | HuMAP2_02728 HuMAP2_04845 |
| NXT1 | HuMAP2_02728 HuMAP2_04845 HuMAP2_05527 |