hu.MAP 2.0: Complex View
Human Protein Complex Map
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Complex: HuMAP2_02731
Confidence: Medium High
Proteins| Genename | Protein Name | Links |
|---|---|---|
| CTPS1 | CTP synthase 1 (EC 6.3.4.2) (CTP synthetase 1) (UTP--ammonia ligase 1) | UniProt NCBI |
| TIGD3 | Tigger transposable element-derived protein 3 | UniProt NCBI |
| SNX3 | Sorting nexin-3 (Protein SDP3) | UniProt NCBI |
| CTPS2 | CTP synthase 2 (EC 6.3.4.2) (CTP synthetase 2) (UTP--ammonia ligase 2) | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| KEGG:00240 | 0.00244394709319 | 0.5 | CTPS1 CTPS2 | Pyrimidine metabolism |
| GO:0003883 | 0.00270494046827 | 0.5 | CTPS1 CTPS2 | CTP synthase activity |
| GO:0006241 | 0.00270494046827 | 0.5 | CTPS1 CTPS2 | CTP biosynthetic process |
| GO:0046036 | 0.00270494046827 | 0.5 | CTPS1 CTPS2 | CTP metabolic process |
| REAC:R-HSA-499943 | 0.00352159938331 | 0.5 | CTPS1 CTPS2 | Interconversion of nucleotide di- and triphosphates |
| WP:WP4022 | 0.00514073093691 | 0.5 | CTPS1 CTPS2 | Pyrimidine metabolism |
| GO:0097268 | 0.00811409485621 | 0.5 | CTPS1 CTPS2 | cytoophidium |
| GO:0009209 | 0.00811409485621 | 0.5 | CTPS1 CTPS2 | pyrimidine ribonucleoside triphosphate biosynthetic process |
| GO:0009148 | 0.0162267366884 | 0.5 | CTPS1 CTPS2 | pyrimidine nucleoside triphosphate biosynthetic process |
| GO:0009208 | 0.0162267366884 | 0.5 | CTPS1 CTPS2 | pyrimidine ribonucleoside triphosphate metabolic process |
| GO:0019856 | 0.0270421395626 | 0.5 | CTPS1 CTPS2 | pyrimidine nucleobase biosynthetic process |
| REAC:R-HSA-15869 | 0.0364771667023 | 0.5 | CTPS1 CTPS2 | Metabolism of nucleotides |
Edges
| Protein 1 | Protein 2 | Score | Precision | Evidence |
|---|---|---|---|---|
| TIGD3 | CTPS2 | 0.13 | 0.401 | bioplex (TIGD3) bioplex_WMM |
| CTPS2 | SNX3 | 0.1 | 0.361 | hein_WMM hein (SNX3) |
| CTPS1 | SNX3 | 0.086 | 0.351 | hein_WMM bioplex_WMM hein (SNX3) gupta_WMM |
| CTPS1 | CTPS2 | 0.069 | 0.348 | hein_WMM bioplex (CTPS2) bioplex_WMM gupta_WMM |
| CTPS1 | TIGD3 | 0.022 | 0.207 | bioplex (TIGD3) bioplex_WMM |
Images
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Complex HuMAP2_02731 has an average edge precision of 0.334 which is ranked 4193 out of all 6965 complexes.
Related Complexes
| Genename | Complexes |
|---|---|
| CTPS1 | HuMAP2_00692 HuMAP2_02731 HuMAP2_05170 HuMAP2_05725 |
| TIGD3 | HuMAP2_00692 HuMAP2_02731 HuMAP2_05170 HuMAP2_05725 |
| SNX3 | HuMAP2_02731 HuMAP2_05725 |
| CTPS2 | HuMAP2_00692 HuMAP2_02731 HuMAP2_05170 HuMAP2_05725 |