hu.MAP 2.0: Complex View
Human Protein Complex Map
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Complex: HuMAP2_02734
Confidence: Medium
Proteins| Genename | Protein Name | Links |
|---|---|---|
| C2CD2 | C2 domain-containing protein 2 (Transmembrane protein 24-like) | UniProt NCBI |
| ARHGAP26 | Rho GTPase-activating protein 26 (GTPase regulator associated with focal adhesion kinase) (Oligophrenin-1-like protein) (Rho-type GTPase-activating protein 26) | UniProt NCBI |
| MICAL1 | [F-actin]-monooxygenase MICAL1 (EC 1.14.13.225) (Molecule interacting with CasL protein 1) (MICAL-1) (NEDD9-interacting protein with calponin homology and LIM domains) | UniProt NCBI |
| ARHGAP42 | Rho GTPase-activating protein 42 (Rho GTPase-activating protein 10-like) (Rho-type GTPase-activating protein 42) | UniProt NCBI |
| ARHGAP10 | Rho GTPase-activating protein 10 (GTPase regulator associated with focal adhesion kinase 2) (Graf-related protein 2) (Rho-type GTPase-activating protein 10) | UniProt NCBI |
| JPH1 | Junctophilin-1 (JP-1) (Junctophilin type 1) | UniProt NCBI |
| SEC14L1 | SEC14-like protein 1 | UniProt NCBI |
| OPHN1 | Oligophrenin-1 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| REAC:R-HSA-194840 | 6.90355722144e-05 | 0.5 | ARHGAP10 ARHGAP26 ARHGAP42 OPHN1 | Rho GTPase cycle |
| REAC:R-HSA-194315 | 0.00775496685796 | 0.5 | ARHGAP10 ARHGAP26 ARHGAP42 OPHN1 | Signaling by Rho GTPases |
| CORUM:5274 | 0.0497224828424 | 0.125 | ARHGAP10 | Cell-cell junction complex (ARHGAP10-CTNNA1) |
Edges
| Protein 1 | Protein 2 | Score | Precision | Evidence |
|---|---|---|---|---|
| ARHGAP26 | ARHGAP10 | 0.981 | 0.896 | bioplex (ARHGAP26) bioplex_WMM boldt boldt_WMM |
| OPHN1 | ARHGAP26 | 0.786 | 0.758 | bioplex (ARHGAP26) bioplex_WMM |
| C2CD2 | ARHGAP26 | 0.651 | 0.69 | bioplex (C2CD2) bioplex_WMM |
| C2CD2 | ARHGAP10 | 0.632 | 0.681 | bioplex (C2CD2) bioplex_WMM |
| ARHGAP42 | ARHGAP26 | 0.431 | 0.578 | bioplex (ARHGAP26) bioplex_WMM |
| C2CD2 | SEC14L1 | 0.067 | 0.351 | bioplex (C2CD2) bioplex_WMM |
| ARHGAP26 | MICAL1 | 0.038 | 0.263 | bioplex (ARHGAP26) bioplex_WMM |
| ARHGAP26 | JPH1 | 0.037 | 0.265 | bioplex (ARHGAP26) bioplex_WMM |
| OPHN1 | ARHGAP10 | 0.008 | 0.091 | bioplex_WMM WMM_only |
| ARHGAP42 | OPHN1 | 0.008 | 0.087 | bioplex_WMM WMM_only |
| SEC14L1 | ARHGAP26 | 0.008 | 0.084 | bioplex_WMM WMM_only |
| SEC14L1 | ARHGAP10 | 0.008 | 0.084 | bioplex_WMM WMM_only |
| ARHGAP42 | ARHGAP10 | 0.008 | 0.067 | bioplex_WMM WMM_only |
| OPHN1 | MICAL1 | 0.008 | 0.046 | bioplex_WMM WMM_only |
| ARHGAP10 | MICAL1 | 0.008 | 0.029 | bioplex_WMM WMM_only |
| OPHN1 | JPH1 | 0.008 | 0.009 | bioplex_WMM WMM_only |
| ARHGAP42 | MICAL1 | 0.007 | 0.01 | bioplex_WMM WMM_only |
| ARHGAP10 | JPH1 | 0.007 | 0.005 | bioplex_WMM WMM_only |
| ARHGAP42 | JPH1 | 0.007 | 0.007 | bioplex_WMM WMM_only |
| MICAL1 | JPH1 | 0.007 | 0.005 | bioplex_WMM WMM_only |
Images
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Complex HuMAP2_02734 has an average edge precision of 0.25 which is ranked 5370 out of all 6965 complexes.
Related Complexes
| Genename | Complexes |
|---|---|
| C2CD2 | HuMAP2_00400 HuMAP2_02734 HuMAP2_03108 HuMAP2_04406 |
| ARHGAP26 | HuMAP2_01128 HuMAP2_02734 HuMAP2_03108 HuMAP2_04406 |
| MICAL1 | HuMAP2_02734 |
| ARHGAP42 | HuMAP2_00991 HuMAP2_01112 HuMAP2_01852 HuMAP2_02734 HuMAP2_03108 HuMAP2_05483 |
| ARHGAP10 | HuMAP2_01128 HuMAP2_02734 HuMAP2_03108 HuMAP2_04406 |
| JPH1 | HuMAP2_02734 HuMAP2_05879 |
| SEC14L1 | HuMAP2_00400 HuMAP2_02734 HuMAP2_03108 |
| OPHN1 | HuMAP2_01128 HuMAP2_02734 HuMAP2_03108 HuMAP2_04406 |