hu.MAP 2.0: Complex View
Human Protein Complex Map
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Complex: HuMAP2_02738
Confidence: Very High
Proteins| Genename | Protein Name | Links |
|---|---|---|
| IFT74 | Intraflagellar transport protein 74 homolog (Capillary morphogenesis gene 1 protein) (CMG-1) (Coiled-coil domain-containing protein 2) | UniProt NCBI |
| IFT46 | Intraflagellar transport protein 46 homolog | UniProt NCBI |
| IFT22 | Intraflagellar transport protein 22 homolog (Rab-like protein 5) | UniProt NCBI |
| TTC30A | Tetratricopeptide repeat protein 30A (TPR repeat protein 30A) | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| REAC:R-HSA-5620924 | 2.26633858062e-08 | 1.0 | IFT22 IFT74 TTC30A IFT46 | Intraflagellar transport |
| GO:0030992 | 5.80614360177e-08 | 1.0 | IFT22 IFT74 TTC30A IFT46 | intraciliary transport particle B |
| CORUM:6173 | 8.09991585269e-08 | 0.75 | IFT74 IFT22 IFT46 | Intraflagellar transport complex B core complex |
| CORUM:6172 | 3.07044439662e-07 | 0.75 | IFT74 IFT22 IFT46 | Intraflagellar transport complex B |
| GO:0030990 | 3.08603851103e-07 | 1.0 | IFT22 IFT74 TTC30A IFT46 | intraciliary transport particle |
| WP:WP4352 | 1.2395315779e-06 | 1.0 | IFT22 IFT74 TTC30A IFT46 | Ciliary landscape |
| REAC:R-HSA-5617833 | 4.87252320159e-06 | 1.0 | IFT22 IFT74 TTC30A IFT46 | Cilium Assembly |
| GO:0042073 | 5.61829777936e-06 | 1.0 | IFT22 IFT74 TTC30A IFT46 | intraciliary transport |
| GO:0098840 | 1.18961295599e-05 | 1.0 | IFT22 IFT74 TTC30A IFT46 | protein transport along microtubule |
| GO:0099118 | 1.18961295599e-05 | 1.0 | IFT22 IFT74 TTC30A IFT46 | microtubule-based protein transport |
| REAC:R-HSA-1852241 | 2.24070737955e-05 | 1.0 | IFT22 IFT74 TTC30A IFT46 | Organelle biogenesis and maintenance |
| GO:0010970 | 0.000268579907655 | 1.0 | IFT22 IFT74 TTC30A IFT46 | transport along microtubule |
| GO:0099111 | 0.000419088323416 | 1.0 | IFT22 IFT74 TTC30A IFT46 | microtubule-based transport |
| GO:0030705 | 0.000521431948115 | 1.0 | IFT22 IFT74 TTC30A IFT46 | cytoskeleton-dependent intracellular transport |
| WP:WP4532 | 0.000588391449758 | 0.5 | IFT46 IFT22 | Intraflagellar transport proteins binding to dynein |
| GO:0031503 | 0.00272272763799 | 1.0 | IFT22 IFT74 TTC30A IFT46 | protein-containing complex localization |
| GO:0007018 | 0.00286921344524 | 1.0 | IFT22 IFT74 TTC30A IFT46 | microtubule-based movement |
| GO:0035735 | 0.00358246159338 | 0.75 | IFT74 IFT22 IFT46 | intraciliary transport involved in cilium assembly |
| GO:0097542 | 0.00480126971785 | 0.75 | IFT74 IFT22 IFT46 | ciliary tip |
| WP:WP4536 | 0.0087458913108 | 0.5 | IFT74 IFT46 | Genes related to primary cilium development (based on CRISPR) |
| GO:0044441 | 0.01169323475 | 1.0 | IFT22 IFT74 TTC30A IFT46 | ciliary part |
| GO:0044782 | 0.0128783441389 | 1.0 | IFT22 IFT74 TTC30A IFT46 | cilium organization |
| GO:0005929 | 0.0272124122863 | 1.0 | IFT22 IFT74 TTC30A IFT46 | cilium |
Edges
| Protein 1 | Protein 2 | Score | Precision | Evidence |
|---|---|---|---|---|
| IFT74 | TTC30A | 0.99 | 0.907 | bioplex (TTC30A) bioplex_WMM boldt (IFT74,TTC30A) boldt_WMM |
| TTC30A | IFT46 | 0.987 | 0.901 | bioplex (TTC30A) bioplex_WMM boldt (IFT46,TTC30A) boldt_WMM |
| TTC30A | IFT22 | 0.838 | 0.782 | bioplex (TTC30A) bioplex_WMM boldt (TTC30A) boldt_WMM |
| IFT74 | IFT46 | 0.702 | 0.723 | bioplex (IFT74) bioplex_WMM boldt (IFT46,IFT74) youn_WMM gupta_WMM boldt_WMM |
| IFT46 | IFT22 | 0.052 | 0.301 | bioplex_WMM boldt (IFT46) gupta_WMM boldt_WMM |
| IFT74 | IFT22 | 0.018 | 0.177 | bioplex (IFT74) bioplex_WMM boldt (IFT22,IFT74) youn_WMM gupta_WMM fraction boldt_WMM |
Images
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Complex HuMAP2_02738 has an average edge precision of 0.632 which is ranked 1774 out of all 6965 complexes.
Related Complexes
| Genename | Complexes |
|---|---|
| IFT74 | HuMAP2_00081 HuMAP2_02738 HuMAP2_04688 |
| IFT46 | HuMAP2_00081 HuMAP2_02738 HuMAP2_04688 |
| IFT22 | HuMAP2_02738 HuMAP2_04688 |
| TTC30A | HuMAP2_00081 HuMAP2_02738 HuMAP2_04688 |