hu.MAP 2.0: Complex View
Human Protein Complex Map
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Complex: HuMAP2_02741
Confidence: Medium High
Proteins| Genename | Protein Name | Links |
|---|---|---|
| RAD18 | E3 ubiquitin-protein ligase RAD18 (EC 2.3.2.27) (Postreplication repair protein RAD18) (hHR18) (hRAD18) (RING finger protein 73) (RING-type E3 ubiquitin transferase RAD18) | UniProt NCBI |
| UBE2A | Ubiquitin-conjugating enzyme E2 A (EC 2.3.2.23) (E2 ubiquitin-conjugating enzyme A) (RAD6 homolog A) (HR6A) (hHR6A) (Ubiquitin carrier protein A) (Ubiquitin-protein ligase A) | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| REAC:R-HSA-8866654 | 0.00258092213206 | 1.0 | RAD18 UBE2A | E3 ubiquitin ligases ubiquitinate target proteins |
| REAC:R-HSA-8852135 | 0.00465068760809 | 1.0 | RAD18 UBE2A | Protein ubiquitination |
| HP:0011913 | 0.0497341708567 | 0.5 | UBE2A | Lumbar hypertrichosis |
Edges
| Protein 1 | Protein 2 | Score | Precision | Evidence |
|---|---|---|---|---|
| UBE2A | RAD18 | 0.064 | 0.347 | hein_WMM bioplex_WMM hein (RAD18,UBE2A) boldt_WMM |
Images
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Complex HuMAP2_02741 has an average edge precision of 0.347 which is ranked 4018 out of all 6965 complexes.
Related Complexes
| Genename | Complexes |
|---|---|
| RAD18 | HuMAP2_01690 HuMAP2_02741 |
| UBE2A | HuMAP2_01337 HuMAP2_01690 HuMAP2_02741 HuMAP2_03854 |