hu.MAP 2.0: Complex View
Human Protein Complex Map
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Complex: HuMAP2_02765
Confidence: Medium
Proteins| Genename | Protein Name | Links |
|---|---|---|
| HINT1 | Histidine triad nucleotide-binding protein 1 (EC 3.-.-.-) (Adenosine 5'-monophosphoramidase) (Protein kinase C inhibitor 1) (Protein kinase C-interacting protein 1) (PKCI-1) | UniProt NCBI |
| NT5DC1 | 5'-nucleotidase domain-containing protein 1 (EC 3.1.3.-) | UniProt NCBI |
| LTA4H | Leukotriene A-4 hydrolase (LTA-4 hydrolase) (EC 3.3.2.6) (Leukotriene A(4) hydrolase) | UniProt NCBI |
| TRAP1 | Heat shock protein 75 kDa, mitochondrial (HSP 75) (TNFR-associated protein 1) (Tumor necrosis factor type 1 receptor-associated protein) (TRAP-1) | UniProt NCBI |
| VCL | Vinculin (Metavinculin) (MV) | UniProt NCBI |
| PITPNB | Phosphatidylinositol transfer protein beta isoform (PI-TP-beta) (PtdIns transfer protein beta) (PtdInsTP beta) | UniProt NCBI |
| PGP | Glycerol-3-phosphate phosphatase (G3PP) (EC 3.1.3.21) (Aspartate-based ubiquitous Mg(2+)-dependent phosphatase) (AUM) (EC 3.1.3.48) (Phosphoglycolate phosphatase) (PGP) | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| CORUM:7324 | 0.0499886427319 | 0.142857142857 | HINT1 | HINT1-TIP60 complex |
| CORUM:7326 | 0.0499886427319 | 0.142857142857 | HINT1 | HINT1-SP1 complex |
Edges
| Protein 1 | Protein 2 | Score | Precision | Evidence |
|---|---|---|---|---|
| LTA4H | VCL | 1.0 | 0.949 | bioplex_WMM fraction treiber_WMM |
| LTA4H | HINT1 | 0.938 | 0.85 | bioplex_WMM fraction |
| LTA4H | TRAP1 | 0.856 | 0.793 | bioplex_WMM fraction treiber_WMM |
| PITPNB | VCL | 0.538 | 0.642 | bioplex_WMM fraction |
| NT5DC1 | PGP | 0.512 | 0.631 | bioplex_WMM fraction |
| LTA4H | NT5DC1 | 0.508 | 0.628 | bioplex_WMM fraction |
| LTA4H | PGP | 0.374 | 0.546 | bioplex_WMM fraction |
| LTA4H | PITPNB | 0.27 | 0.483 | bioplex_WMM fraction |
| TRAP1 | VCL | 0.203 | 0.453 | hein_WMM bioplex_WMM boldt fraction boldt_WMM treiber_WMM |
| PGP | VCL | 0.134 | 0.406 | bioplex_WMM fraction |
| PGP | HINT1 | 0.014 | 0.141 | bioplex_WMM Guru fraction |
| PGP | PITPNB | 0.005 | 0.011 | bioplex_WMM fraction |
| NT5DC1 | VCL | 0.004 | 0.01 | bioplex (NT5DC1) bioplex_WMM fraction |
| HINT1 | VCL | 0.003 | 0.008 | bioplex_WMM Guru youn_WMM gupta_WMM fraction |
| NT5DC1 | PITPNB | 0.0 | 0.009 | bioplex_WMM WMM_only |
| PGP | TRAP1 | 0.0 | 0.013 | bioplex_WMM fraction |
| NT5DC1 | TRAP1 | 0.0 | 0.011 | bioplex (NT5DC1) bioplex_WMM fraction |
| TRAP1 | PITPNB | 0.0 | 0.01 | hein_WMM bioplex_WMM fraction |
| NT5DC1 | HINT1 | 0.0 | 0.008 | bioplex_WMM fraction |
| HINT1 | TRAP1 | 0.0 | 0.001 | bioplex_WMM fraction |
| HINT1 | PITPNB | 0.0 | 0.001 | bioplex_WMM fraction |
Images
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Complex HuMAP2_02765 has an average edge precision of 0.314 which is ranked 4415 out of all 6965 complexes.
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