hu.MAP 2.0: Complex View
Human Protein Complex Map
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Complex: HuMAP2_02775
Confidence: Medium
Proteins| Genename | Protein Name | Links |
|---|---|---|
| EHD4 | EH domain-containing protein 4 (Hepatocellular carcinoma-associated protein 10/11) (PAST homolog 4) | UniProt NCBI |
| EHD3 | EH domain-containing protein 3 (PAST homolog 3) | UniProt NCBI |
| RBSN | Rabenosyn-5 (110 kDa protein) (FYVE finger-containing Rab5 effector protein rabenosyn-5) (RAB effector RBSN) (Zinc finger FYVE domain-containing protein 20) | UniProt NCBI |
| GALE | UDP-glucose 4-epimerase (EC 5.1.3.2) (Galactowaldenase) (UDP-N-acetylgalactosamine 4-epimerase) (UDP-GalNAc 4-epimerase) (UDP-N-acetylglucosamine 4-epimerase) (UDP-GlcNAc 4-epimerase) (EC 5.1.3.7) (UDP-galactose 4-epimerase) | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| KEGG:04144 | 0.000539397470166 | 0.75 | RBSN EHD3 EHD4 | Endocytosis |
| HPA:024010_22 | 0.015593530775 | 1.0 | RBSN EHD3 GALE EHD4 | kidney; cells in glomeruli[Approved,Medium] |
| HPA:028010_22 | 0.0198210730397 | 1.0 | RBSN EHD3 GALE EHD4 | lymph node; germinal center cells[Approved,Medium] |
| REAC:R-HSA-5609977 | 0.0499190562503 | 0.25 | GALE | Defective GALE can cause Epimerase-deficiency galactosemia (EDG) |
Edges
| Protein 1 | Protein 2 | Score | Precision | Evidence |
|---|---|---|---|---|
| RBSN | EHD3 | 0.191 | 0.444 | bioplex (RBSN) bioplex_WMM |
| RBSN | EHD4 | 0.083 | 0.349 | bioplex (RBSN) bioplex_WMM |
| GALE | EHD4 | 0.028 | 0.231 | Guru fraction |
| EHD3 | EHD4 | 0.008 | 0.011 | bioplex_WMM WMM_only boldt_WMM |
Images
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Complex HuMAP2_02775 has an average edge precision of 0.259 which is ranked 5246 out of all 6965 complexes.
Related Complexes