hu.MAP 2.0: Complex View
Human Protein Complex Map
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Complex: HuMAP2_02778
Confidence: Medium
Proteins| Genename | Protein Name | Links |
|---|---|---|
| TAF12 | Transcription initiation factor TFIID subunit 12 (Transcription initiation factor TFIID 20/15 kDa subunits) (TAFII-20/TAFII-15) (TAFII20/TAFII15) | UniProt NCBI |
| SUPT20H | Transcription factor SPT20 homolog (p38-interacting protein) (p38IP) | UniProt NCBI |
| TADA3 | Transcriptional adapter 3 (ADA3 homolog) (hADA3) (STAF54) (Transcriptional adapter 3-like) (ADA3-like protein) | UniProt NCBI |
| SUPT7L | STAGA complex 65 subunit gamma (Adenocarcinoma antigen ART1) (SPTF-associated factor 65 gamma) (STAF65gamma) (Suppressor of Ty 7-like) | UniProt NCBI |
| TADA1 | Transcriptional adapter 1 (SPT3-associated factor 42) (STAF42) (Transcriptional adapter 1-like protein) | UniProt NCBI |
| TAF6L | TAF6-like RNA polymerase II p300/CBP-associated factor-associated factor 65 kDa subunit 6L (PCAF-associated factor 65-alpha) (PAF65-alpha) | UniProt NCBI |
| TADA2B | Transcriptional adapter 2-beta (ADA2-like protein beta) (ADA2-beta) | UniProt NCBI |
| TAF5L | TAF5-like RNA polymerase II p300/CBP-associated factor-associated factor 65 kDa subunit 5L (PCAF-associated factor 65 beta) (PAF65-beta) | UniProt NCBI |
| SUPT3H | Transcription initiation protein SPT3 homolog (SPT3-like protein) | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| CORUM:6664 | 2.02633105518e-26 | 1.0 | TAF12 TADA1 TAF6L TADA2B SUPT3H SUPT20H TADA3 TAF5L SUPT7L | STAGA complex, SPT3-linked |
| CORUM:6643 | 4.68604530311e-22 | 0.888888888889 | TAF12 SUPT3H TAF6L SUPT7L SUPT20H TADA3 TAF5L TADA2B | SAGA complex, GCN5-linked |
| GO:0070461 | 1.03025295389e-21 | 1.0 | TAF12 TADA1 TAF6L TADA2B SUPT3H SUPT20H TADA3 TAF5L SUPT7L | SAGA-type complex |
| CORUM:476 | 3.65527897904e-20 | 0.777777777778 | TAF12 TADA1 TAF6L SUPT7L SUPT3H TADA3 TAF5L | STAGA complex |
| CORUM:475 | 3.65527897904e-20 | 0.777777777778 | TAF12 TADA1 TAF6L SUPT7L SUPT3H TADA3 TAF5L | STAGA complex |
| GO:0030914 | 1.84308652766e-17 | 0.777777777778 | TAF12 TADA1 TAF6L SUPT7L SUPT3H TADA3 TAF5L | STAGA complex |
| GO:0000123 | 9.19647578982e-17 | 1.0 | TAF12 TADA1 TAF6L TADA2B SUPT3H SUPT20H TADA3 TAF5L SUPT7L | histone acetyltransferase complex |
| REAC:R-HSA-3214847 | 1.00339396271e-16 | 1.0 | TAF12 TADA1 TAF6L TADA2B SUPT3H SUPT20H TADA3 TAF5L SUPT7L | HATs acetylate histones |
| GO:1902493 | 2.88126578321e-16 | 1.0 | TAF12 TADA1 TAF6L TADA2B SUPT3H SUPT20H TADA3 TAF5L SUPT7L | acetyltransferase complex |
| GO:0031248 | 2.88126578321e-16 | 1.0 | TAF12 TADA1 TAF6L TADA2B SUPT3H SUPT20H TADA3 TAF5L SUPT7L | protein acetyltransferase complex |
| GO:0004402 | 1.06328988676e-14 | 0.888888888889 | TAF12 TADA1 TAF6L TADA2B SUPT3H TADA3 TAF5L SUPT7L | histone acetyltransferase activity |
| GO:0061733 | 1.43461850928e-14 | 0.888888888889 | TAF12 TADA1 TAF6L TADA2B SUPT3H TADA3 TAF5L SUPT7L | peptide-lysine-N-acetyltransferase activity |
| REAC:R-HSA-3247509 | 3.56673942132e-14 | 1.0 | TAF12 TADA1 TAF6L TADA2B SUPT3H SUPT20H TADA3 TAF5L SUPT7L | Chromatin modifying enzymes |
| REAC:R-HSA-4839726 | 3.56673942132e-14 | 1.0 | TAF12 TADA1 TAF6L TADA2B SUPT3H SUPT20H TADA3 TAF5L SUPT7L | Chromatin organization |
| GO:0034212 | 4.87900146463e-14 | 0.888888888889 | TAF12 TADA1 TAF6L TADA2B SUPT3H TADA3 TAF5L SUPT7L | peptide N-acetyltransferase activity |
| GO:0008080 | 1.57309255491e-13 | 0.888888888889 | TAF12 TADA1 TAF6L TADA2B SUPT3H TADA3 TAF5L SUPT7L | N-acetyltransferase activity |
| CORUM:477 | 2.14726471161e-13 | 0.555555555556 | TAF6L TAF12 TAF5L SUPT3H TADA3 | PCAF complex |
| CORUM:471 | 2.14726471161e-13 | 0.555555555556 | TAF6L TAF12 TAF5L SUPT3H TADA3 | PCAF complex |
| GO:0016410 | 5.79049604675e-13 | 0.888888888889 | TAF12 TADA1 TAF6L TADA2B SUPT3H TADA3 TAF5L SUPT7L | N-acyltransferase activity |
| GO:0016407 | 9.90187768428e-13 | 0.888888888889 | TAF12 TADA1 TAF6L TADA2B SUPT3H TADA3 TAF5L SUPT7L | acetyltransferase activity |
| GO:0016573 | 2.43239648597e-12 | 0.888888888889 | TAF12 TADA1 TAF6L TADA2B SUPT3H TADA3 TAF5L SUPT7L | histone acetylation |
| CORUM:462 | 2.55595970459e-12 | 0.555555555556 | TAF6L TAF12 TAF5L SUPT3H TADA3 | TFTC complex (TATA-binding protein-free TAF-II-containing complex) |
| CORUM:455 | 2.55595970459e-12 | 0.555555555556 | TAF6L TAF12 TAF5L SUPT3H TADA3 | TFTC complex (TATA-binding protein-free TAF-II-containing complex) |
| CORUM:456 | 2.55595970459e-12 | 0.555555555556 | TAF6L TAF12 TAF5L SUPT3H TADA3 | TFTC complex (TATA-binding protein-free TAF-II-containing complex) |
| CORUM:445 | 2.55595970459e-12 | 0.555555555556 | TAF6L TAF12 TAF5L SUPT3H TADA3 | TFTC complex (TATA-binding protein-free TAF-II-containing complex) |
| GO:0018393 | 2.83472588394e-12 | 0.888888888889 | TAF12 TADA1 TAF6L TADA2B SUPT3H TADA3 TAF5L SUPT7L | internal peptidyl-lysine acetylation |
| CORUM:513 | 3.7169268162e-12 | 0.555555555556 | TAF6L TAF12 TAF5L SUPT3H TADA3 | TFTC complex (TATA-binding protein-free TAF-II-containing complex) |
| CORUM:470 | 3.7169268162e-12 | 0.555555555556 | TAF6L TAF12 TAF5L SUPT3H TADA3 | TFTC complex (TATA-binding protein-free TAF-II-containing complex) |
| GO:0006475 | 4.10517503321e-12 | 0.888888888889 | TAF12 TADA1 TAF6L TADA2B SUPT3H TADA3 TAF5L SUPT7L | internal protein amino acid acetylation |
| GO:0018394 | 4.41183886913e-12 | 0.888888888889 | TAF12 TADA1 TAF6L TADA2B SUPT3H TADA3 TAF5L SUPT7L | peptidyl-lysine acetylation |
| GO:0043966 | 5.55310186732e-12 | 0.777777777778 | TAF12 TADA1 TAF6L SUPT7L SUPT3H TADA3 TAF5L | histone H3 acetylation |
| GO:0006473 | 3.31658234125e-11 | 0.888888888889 | TAF12 TADA1 TAF6L TADA2B SUPT3H TADA3 TAF5L SUPT7L | protein acetylation |
| GO:0043543 | 1.89767498809e-10 | 0.888888888889 | TAF12 TADA1 TAF6L TADA2B SUPT3H TADA3 TAF5L SUPT7L | protein acylation |
| GO:0016747 | 2.07437665339e-10 | 0.888888888889 | TAF12 TADA1 TAF6L TADA2B SUPT3H TADA3 TAF5L SUPT7L | transferase activity, transferring acyl groups other than amino-acyl groups |
| GO:0016746 | 5.40806342262e-10 | 0.888888888889 | TAF12 TADA1 TAF6L TADA2B SUPT3H TADA3 TAF5L SUPT7L | transferase activity, transferring acyl groups |
| GO:0003713 | 5.73379806422e-09 | 0.888888888889 | TAF12 TADA1 TAF6L TADA2B SUPT3H TADA3 TAF5L SUPT7L | transcription coactivator activity |
| GO:0018205 | 7.42509028435e-09 | 0.888888888889 | TAF12 TADA1 TAF6L TADA2B SUPT3H TADA3 TAF5L SUPT7L | peptidyl-lysine modification |
| GO:0016570 | 2.08448274487e-08 | 0.888888888889 | TAF12 TADA1 TAF6L TADA2B SUPT3H TADA3 TAF5L SUPT7L | histone modification |
| GO:0016569 | 2.9994528829e-08 | 0.888888888889 | TAF12 TADA1 TAF6L TADA2B SUPT3H TADA3 TAF5L SUPT7L | covalent chromatin modification |
| GO:1990234 | 5.25719457291e-08 | 1.0 | TAF12 TADA1 TAF6L TADA2B SUPT3H SUPT20H TADA3 TAF5L SUPT7L | transferase complex |
| GO:0003712 | 4.27319045693e-07 | 0.888888888889 | TAF12 TADA1 TAF6L TADA2B SUPT3H TADA3 TAF5L SUPT7L | transcription coregulator activity |
| GO:0044451 | 6.24729577516e-07 | 1.0 | TAF12 TADA1 TAF6L TADA2B SUPT3H SUPT20H TADA3 TAF5L SUPT7L | nucleoplasm part |
| CORUM:438 | 7.54972137794e-07 | 0.333333333333 | TADA3 TAF5L SUPT3H | GCN5-TRRAP histone acetyltransferase complex |
| GO:0000124 | 1.01246124774e-06 | 0.444444444444 | TADA3 TADA1 SUPT20H TAF12 | SAGA complex |
| GO:0006325 | 2.25523237578e-06 | 0.888888888889 | TAF12 TADA1 TAF6L TADA2B SUPT3H TADA3 TAF5L SUPT7L | chromatin organization |
| GO:0033276 | 3.06865717378e-06 | 0.444444444444 | TADA3 TAF5L SUPT3H TAF12 | transcription factor TFTC complex |
| GO:1902494 | 6.70061170383e-06 | 1.0 | TAF12 TADA1 TAF6L TADA2B SUPT3H SUPT20H TADA3 TAF5L SUPT7L | catalytic complex |
| GO:0018193 | 5.87460343344e-05 | 0.888888888889 | TAF12 TADA1 TAF6L TADA2B SUPT3H TADA3 TAF5L SUPT7L | peptidyl-amino acid modification |
| CORUM:0000000 | 7.29350199909e-05 | 1.0 | TAF12 TADA1 TAF6L TADA2B SUPT3H SUPT20H TADA3 TAF5L SUPT7L | CORUM root |
| KEGG:03022 | 8.8588800407e-05 | 0.333333333333 | TAF6L TAF5L TAF12 | Basal transcription factors |
| GO:0051276 | 9.38953674575e-05 | 0.888888888889 | TAF12 TADA1 TAF6L TADA2B SUPT3H TADA3 TAF5L SUPT7L | chromosome organization |
| CORUM:6641 | 0.000374856382464 | 0.222222222222 | TADA3 TADA2B | USP22-SAGA complex |
| GO:0140110 | 0.00107701684708 | 0.888888888889 | TAF12 TADA1 TAF6L TADA2B SUPT3H TADA3 TAF5L SUPT7L | transcription regulator activity |
| GO:0016591 | 0.00310500088273 | 0.444444444444 | TADA3 TAF5L SUPT3H TAF12 | RNA polymerase II, holoenzyme |
| GO:1905368 | 0.00328411577048 | 0.444444444444 | TADA3 TADA1 SUPT20H TAF12 | peptidase complex |
| GO:0006366 | 0.00553073226606 | 0.888888888889 | TAF12 TADA1 TAF6L TADA2B SUPT3H SUPT20H TADA3 TAF5L | transcription by RNA polymerase II |
| GO:0055029 | 0.00996136852053 | 0.444444444444 | TADA3 TAF5L SUPT3H TAF12 | nuclear DNA-directed RNA polymerase complex |
| GO:0000428 | 0.0103870118672 | 0.444444444444 | TADA3 TAF5L SUPT3H TAF12 | DNA-directed RNA polymerase complex |
| GO:0030880 | 0.01174566688 | 0.444444444444 | TADA3 TAF5L SUPT3H TAF12 | RNA polymerase complex |
| GO:0016740 | 0.0198541477682 | 0.888888888889 | TAF12 TADA1 TAF6L TADA2B SUPT3H TADA3 TAF5L SUPT7L | transferase activity |
| GO:0005654 | 0.0467384203064 | 1.0 | TAF12 TADA1 TAF6L TADA2B SUPT3H SUPT20H TADA3 TAF5L SUPT7L | nucleoplasm |
| CORUM:497 | 0.0499262710315 | 0.111111111111 | TAF12 | TAF4-TAF12 subcomplex of TFIID complex |
| CORUM:1317 | 0.0499262710315 | 0.111111111111 | TAF12 | ATF7-TAF12 complex |
Edges
| Protein 1 | Protein 2 | Score | Precision | Evidence |
|---|---|---|---|---|
| SUPT7L | TADA1 | 0.995 | 0.924 | hein_WMM bioplex (TADA1) bioplex_WMM youn_WMM boldt_WMM |
| SUPT7L | TADA2B | 0.98 | 0.896 | hein_WMM bioplex (TADA2B) bioplex_WMM youn_WMM boldt_WMM |
| SUPT20H | TADA2B | 0.977 | 0.892 | hein_WMM bioplex (TADA2B) bioplex_WMM youn_WMM boldt_WMM |
| TADA1 | TAF5L | 0.974 | 0.886 | hein_WMM bioplex (TADA1) bioplex_WMM youn_WMM boldt_WMM |
| TADA1 | TADA2B | 0.888 | 0.818 | hein_WMM bioplex (TADA1,TADA2B) bioplex_WMM youn_WMM boldt_WMM |
| TADA3 | TADA2B | 0.881 | 0.815 | hein_WMM bioplex (TADA2B,TADA3) bioplex_WMM youn_WMM boldt_WMM |
| SUPT20H | TADA3 | 0.742 | 0.74 | hein_WMM bioplex (TADA3) bioplex_WMM youn_WMM boldt_WMM |
| TAF6L | TADA2B | 0.734 | 0.738 | hein_WMM bioplex (TADA2B,TAF6L) bioplex_WMM youn_WMM boldt_WMM |
| SUPT3H | TAF5L | 0.729 | 0.735 | hein_WMM bioplex (TAF5L) bioplex_WMM youn_WMM |
| SUPT3H | TADA2B | 0.669 | 0.702 | hein_WMM bioplex (TADA2B) bioplex_WMM youn_WMM |
| TADA3 | TADA1 | 0.666 | 0.701 | hein_WMM bioplex (TADA3) bioplex_WMM youn_WMM boldt_WMM |
| TAF6L | TADA1 | 0.622 | 0.677 | hein_WMM bioplex (TADA1,TAF6L) bioplex_WMM youn_WMM boldt_WMM |
| TADA1 | TAF12 | 0.355 | 0.539 | bioplex (TADA1) bioplex_WMM |
| TAF6L | SUPT7L | 0.327 | 0.516 | hein_WMM bioplex (TAF6L) bioplex_WMM youn_WMM boldt_WMM |
| TADA3 | SUPT7L | 0.318 | 0.51 | hein_WMM bioplex (TADA3) bioplex_WMM youn_WMM boldt_WMM |
| TADA3 | TAF12 | 0.254 | 0.478 | bioplex (TADA3) bioplex_WMM gupta_WMM |
| TADA2B | TAF12 | 0.216 | 0.464 | bioplex (TADA2B) bioplex_WMM |
| TADA3 | TAF5L | 0.21 | 0.457 | hein_WMM bioplex (TADA3) bioplex_WMM youn_WMM boldt_WMM |
| SUPT3H | TAF6L | 0.189 | 0.441 | hein_WMM bioplex (TAF6L) bioplex_WMM youn_WMM |
| TAF6L | TAF5L | 0.151 | 0.411 | hein_WMM bioplex (TAF5L,TAF6L) bioplex_WMM youn_WMM boldt_WMM |
| SUPT20H | TADA1 | 0.115 | 0.384 | hein_WMM bioplex (TADA1) bioplex_WMM youn_WMM boldt_WMM |
| TADA2B | TAF5L | 0.111 | 0.381 | hein_WMM bioplex (TADA2B,TAF5L) bioplex_WMM youn_WMM boldt_WMM |
| SUPT20H | TAF6L | 0.103 | 0.365 | hein_WMM bioplex (TAF6L) bioplex_WMM youn_WMM boldt_WMM |
| SUPT3H | TADA3 | 0.064 | 0.348 | hein_WMM bioplex (TADA3) bioplex_WMM youn_WMM |
| TAF6L | TAF12 | 0.047 | 0.293 | bioplex (TAF6L) bioplex_WMM gupta_WMM |
| SUPT20H | SUPT7L | 0.039 | 0.266 | hein_WMM bioplex_WMM youn_WMM WMM_only boldt_WMM |
| SUPT7L | TAF5L | 0.039 | 0.264 | hein_WMM bioplex_WMM youn_WMM WMM_only boldt_WMM |
| SUPT20H | TAF5L | 0.037 | 0.263 | hein_WMM bioplex_WMM youn_WMM WMM_only boldt_WMM |
| SUPT3H | SUPT7L | 0.031 | 0.24 | hein_WMM bioplex_WMM youn_WMM WMM_only |
| TAF6L | TADA3 | 0.027 | 0.232 | hein_WMM bioplex (TADA3,TAF6L) bioplex_WMM youn_WMM boldt_WMM |
| SUPT3H | TADA1 | 0.026 | 0.218 | hein_WMM bioplex_WMM youn_WMM WMM_only |
| SUPT20H | SUPT3H | 0.023 | 0.206 | hein_WMM bioplex_WMM youn_WMM WMM_only |
| SUPT7L | TAF12 | 0.019 | 0.181 | bioplex_WMM WMM_only |
| TAF5L | TAF12 | 0.016 | 0.156 | bioplex_WMM WMM_only |
| SUPT20H | TAF12 | 0.015 | 0.15 | bioplex_WMM WMM_only |
| SUPT3H | TAF12 | 0.014 | 0.145 | bioplex_WMM WMM_only |
Images
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Complex HuMAP2_02778 has an average edge precision of 0.484 which is ranked 2598 out of all 6965 complexes.
Related Complexes