hu.MAP 2.0: Complex View
Human Protein Complex Map
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Complex: HuMAP2_02781
Confidence: Very High
Proteins| Genename | Protein Name | Links |
|---|---|---|
| NCAPH | Condensin complex subunit 2 (Barren homolog protein 1) (Chromosome-associated protein H) (hCAP-H) (Non-SMC condensin I complex subunit H) (XCAP-H homolog) | UniProt NCBI |
| NCAPD2 | Condensin complex subunit 1 (Chromosome condensation-related SMC-associated protein 1) (Chromosome-associated protein D2) (hCAP-D2) (Non-SMC condensin I complex subunit D2) (XCAP-D2 homolog) | UniProt NCBI |
| SMC2 | Structural maintenance of chromosomes protein 2 (SMC protein 2) (SMC-2) (Chromosome-associated protein E) (hCAP-E) (XCAP-E homolog) | UniProt NCBI |
| SMC4 | Structural maintenance of chromosomes protein 4 (SMC protein 4) (SMC-4) (Chromosome-associated polypeptide C) (hCAP-C) (XCAP-C homolog) | UniProt NCBI |
| NCAPG | Condensin complex subunit 3 (Chromosome-associated protein G) (Condensin subunit CAP-G) (hCAP-G) (Melanoma antigen NY-MEL-3) (Non-SMC condensin I complex subunit G) (XCAP-G homolog) | UniProt NCBI |
| NCAPD3 | Condensin-2 complex subunit D3 (Non-SMC condensin II complex subunit D3) (hCAP-D3) | UniProt NCBI |
| NCAPG2 | Condensin-2 complex subunit G2 (Chromosome-associated protein G2) (CAP-G2) (hCAP-G2) (Leucine zipper protein 5) (Non-SMC condensin II complex subunit G2) | UniProt NCBI |
| NCAPH2 | Condensin-2 complex subunit H2 (Chromosome-associated protein H2) (hCAP-H2) (Kleisin-beta) (Non-SMC condensin II complex subunit H2) | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| GO:0000796 | 1.24171952415e-20 | 0.875 | NCAPH NCAPH2 NCAPD2 NCAPD3 NCAPG SMC2 SMC4 | condensin complex |
| GO:0007076 | 1.41977569805e-16 | 0.875 | NCAPH NCAPH2 NCAPD2 NCAPD3 NCAPG SMC2 SMC4 | mitotic chromosome condensation |
| CORUM:167 | 4.24766632997e-16 | 0.625 | NCAPH NCAPG SMC2 NCAPD2 SMC4 | Condensin I complex |
| CORUM:160 | 4.24766632997e-16 | 0.625 | SMC2 NCAPD3 NCAPH2 NCAPG2 SMC4 | Condensin II |
| CORUM:157 | 4.24766632997e-16 | 0.625 | NCAPH NCAPG SMC2 NCAPD2 SMC4 | Condensin I complex |
| CORUM:10 | 4.24766632997e-16 | 0.625 | NCAPH NCAPG SMC2 NCAPD2 SMC4 | Condensin I complex |
| CORUM:159 | 8.91710393203e-15 | 0.625 | NCAPH NCAPG SMC2 NCAPD2 SMC4 | Condensin I-PARP-1-XRCC1 complex |
| GO:0030261 | 5.29657890113e-14 | 0.875 | NCAPH NCAPH2 NCAPD2 NCAPD3 NCAPG SMC2 SMC4 | chromosome condensation |
| REAC:R-HSA-2514853 | 7.50808861849e-13 | 0.625 | NCAPH NCAPG SMC2 NCAPD2 SMC4 | Condensation of Prometaphase Chromosomes |
| GO:0044815 | 6.08698770013e-12 | 0.875 | NCAPH NCAPH2 NCAPD2 NCAPD3 NCAPG SMC2 SMC4 | DNA packaging complex |
| REAC:R-HSA-68886 | 2.77783317385e-11 | 1.0 | NCAPH NCAPH2 NCAPD2 NCAPD3 SMC4 SMC2 NCAPG2 NCAPG | M Phase |
| REAC:R-HSA-69278 | 3.49110510408e-10 | 1.0 | NCAPH NCAPH2 NCAPD2 NCAPD3 SMC4 SMC2 NCAPG2 NCAPG | Cell Cycle, Mitotic |
| GO:0000793 | 4.76568024147e-10 | 0.875 | NCAPH NCAPH2 NCAPD2 NCAPD3 NCAPG SMC2 SMC4 | condensed chromosome |
| REAC:R-HSA-1640170 | 1.49141200565e-09 | 1.0 | NCAPH NCAPH2 NCAPD2 NCAPD3 SMC4 SMC2 NCAPG2 NCAPG | Cell Cycle |
| GO:0000070 | 2.10210281502e-09 | 0.875 | NCAPH NCAPH2 NCAPD2 NCAPD3 NCAPG SMC2 SMC4 | mitotic sister chromatid segregation |
| GO:0000819 | 7.14355500843e-09 | 0.875 | NCAPH NCAPH2 NCAPD2 NCAPD3 NCAPG SMC2 SMC4 | sister chromatid segregation |
| GO:0006323 | 8.83505814658e-09 | 0.875 | NCAPH NCAPH2 NCAPD2 NCAPD3 NCAPG SMC2 SMC4 | DNA packaging |
| REAC:R-HSA-2299718 | 2.25058784481e-08 | 0.625 | SMC2 NCAPD3 NCAPH2 NCAPG2 SMC4 | Condensation of Prophase Chromosomes |
| GO:0098813 | 3.57867747938e-08 | 0.875 | NCAPH NCAPH2 NCAPD2 NCAPD3 NCAPG SMC2 SMC4 | nuclear chromosome segregation |
| GO:0140014 | 6.87947888715e-08 | 0.875 | NCAPH NCAPH2 NCAPD2 NCAPD3 NCAPG SMC2 SMC4 | mitotic nuclear division |
| GO:0071103 | 8.52961532095e-08 | 0.875 | NCAPH NCAPH2 NCAPD2 NCAPD3 NCAPG SMC2 SMC4 | DNA conformation change |
| GO:0007059 | 1.440757743e-07 | 0.875 | NCAPH NCAPH2 NCAPD2 NCAPD3 NCAPG SMC2 SMC4 | chromosome segregation |
| REAC:R-HSA-68875 | 4.92537449059e-07 | 0.625 | SMC2 NCAPD3 NCAPH2 NCAPG2 SMC4 | Mitotic Prophase |
| GO:0000280 | 5.94120228736e-07 | 0.875 | NCAPH NCAPH2 NCAPD2 NCAPD3 NCAPG SMC2 SMC4 | nuclear division |
| GO:0048285 | 1.32132314227e-06 | 0.875 | NCAPH NCAPH2 NCAPD2 NCAPD3 NCAPG SMC2 SMC4 | organelle fission |
| REAC:R-HSA-68877 | 3.16782196308e-06 | 0.625 | NCAPH NCAPG SMC2 NCAPD2 SMC4 | Mitotic Prometaphase |
| GO:0010032 | 5.08584025729e-06 | 0.375 | NCAPD3 NCAPD2 NCAPH2 | meiotic chromosome condensation |
| GO:0000799 | 5.08584025729e-06 | 0.375 | NCAPH NCAPD2 NCAPD3 | nuclear condensin complex |
| CORUM:5239 | 1.16880143691e-05 | 0.25 | SMC2 SMC4 | CAP(C)-CAP(E) complex |
| CORUM:353 | 3.50546248845e-05 | 0.25 | SMC2 SMC4 | DNA ligase IV-condensin complex |
| GO:1903047 | 0.000216887976765 | 0.875 | NCAPH NCAPH2 NCAPD2 NCAPD3 NCAPG SMC2 SMC4 | mitotic cell cycle process |
| CORUM:49 | 0.000245118829946 | 0.25 | SMC2 SMC4 | DNMT3B complex |
| CORUM:0000000 | 0.000356401437906 | 1.0 | NCAPH NCAPH2 NCAPD2 NCAPD3 SMC4 SMC2 NCAPG2 NCAPG | CORUM root |
| GO:0000278 | 0.00063078166759 | 0.875 | NCAPH NCAPH2 NCAPD2 NCAPD3 NCAPG SMC2 SMC4 | mitotic cell cycle |
| GO:0051276 | 0.00135023127082 | 0.875 | NCAPH NCAPH2 NCAPD2 NCAPD3 NCAPG SMC2 SMC4 | chromosome organization |
| GO:0022402 | 0.0042701794658 | 0.875 | NCAPH NCAPH2 NCAPD2 NCAPD3 NCAPG SMC2 SMC4 | cell cycle process |
| GO:0044427 | 0.00920243635931 | 0.875 | NCAPH NCAPH2 NCAPD2 NCAPD3 NCAPG SMC2 SMC4 | chromosomal part |
| GO:0070192 | 0.0102394198288 | 0.375 | NCAPD3 NCAPD2 NCAPH2 | chromosome organization involved in meiotic cell cycle |
| GO:0005694 | 0.0118244000094 | 0.875 | NCAPH NCAPH2 NCAPD2 NCAPD3 NCAPG SMC2 SMC4 | chromosome |
| GO:0007049 | 0.0140553715629 | 0.875 | NCAPH NCAPH2 NCAPD2 NCAPD3 NCAPG SMC2 SMC4 | cell cycle |
| HP:0000340 | 0.0271205121542 | 0.375 | NCAPH NCAPD2 NCAPD3 | Sloping forehead |
Edges
| Protein 1 | Protein 2 | Score | Precision | Evidence |
|---|---|---|---|---|
| NCAPG2 | NCAPD3 | 1.0 | 0.949 | hein_WMM bioplex_WMM youn_WMM hein (NCAPD3,NCAPG2) Malo fraction |
| SMC4 | SMC2 | 1.0 | 0.949 | hein_WMM bioplex_WMM boldt youn_WMM hein (SMC4) Malo gupta_WMM fraction boldt_WMM treiber_WMM |
| NCAPG2 | NCAPH2 | 1.0 | 0.949 | hein_WMM bioplex (NCAPH2) bioplex_WMM boldt hein (NCAPG2) Malo fraction boldt_WMM |
| NCAPG | NCAPH | 1.0 | 0.949 | hein_WMM bioplex_WMM youn_WMM hein (NCAPH) Malo gupta_WMM fraction |
| NCAPD2 | NCAPH | 1.0 | 0.949 | hein_WMM bioplex_WMM youn_WMM hein (NCAPH) Malo fraction boldt_WMM |
| NCAPH2 | NCAPD3 | 1.0 | 0.949 | hein_WMM bioplex (NCAPH2) bioplex_WMM hein (NCAPD3) Malo fraction |
| SMC4 | NCAPH2 | 0.999 | 0.949 | hein_WMM bioplex (NCAPH2) bioplex_WMM boldt hein (SMC4) fraction boldt_WMM |
| NCAPH | SMC2 | 0.998 | 0.936 | hein_WMM bioplex_WMM youn_WMM hein (NCAPH) gupta_WMM fraction boldt_WMM |
| NCAPG2 | SMC4 | 0.989 | 0.902 | hein_WMM bioplex_WMM boldt youn_WMM hein (NCAPG2,SMC4) fraction boldt_WMM |
| NCAPD2 | NCAPG | 0.988 | 0.901 | hein_WMM bioplex_WMM youn_WMM Malo gupta_WMM fraction treiber_WMM |
| SMC4 | NCAPH | 0.988 | 0.901 | hein_WMM bioplex_WMM youn_WMM hein (NCAPH,SMC4) gupta_WMM fraction boldt_WMM |
| NCAPD2 | SMC4 | 0.988 | 0.901 | hein_WMM bioplex_WMM boldt youn_WMM hein (SMC4) fraction boldt_WMM treiber_WMM |
| SMC4 | NCAPG | 0.988 | 0.901 | hein_WMM bioplex_WMM boldt youn_WMM hein (SMC4) gupta_WMM fraction boldt_WMM treiber_WMM |
| SMC2 | NCAPD3 | 0.968 | 0.88 | hein_WMM bioplex_WMM youn_WMM hein (NCAPD3) fraction |
| NCAPH2 | SMC2 | 0.93 | 0.846 | hein_WMM bioplex (NCAPH2) bioplex_WMM boldt fraction boldt_WMM |
| NCAPG2 | SMC2 | 0.82 | 0.773 | hein_WMM bioplex_WMM boldt youn_WMM hein (NCAPG2) fraction boldt_WMM |
| SMC4 | NCAPD3 | 0.774 | 0.752 | hein_WMM bioplex_WMM youn_WMM hein (NCAPD3,SMC4) fraction treiber_WMM |
| NCAPD2 | SMC2 | 0.252 | 0.476 | hein_WMM bioplex_WMM boldt youn_WMM fraction boldt_WMM treiber_WMM |
| NCAPG | SMC2 | 0.114 | 0.384 | hein_WMM bioplex_WMM youn_WMM gupta_WMM fraction treiber_WMM |
| NCAPD2 | NCAPH2 | 0.007 | 0.004 | hein_WMM bioplex_WMM WMM_only |
| NCAPG2 | NCAPG | 0.007 | 0.001 | hein_WMM bioplex_WMM youn_WMM WMM_only boldt_WMM |
| NCAPD2 | NCAPD3 | 0.007 | 0.006 | hein_WMM bioplex_WMM youn_WMM WMM_only treiber_WMM |
| NCAPG | NCAPD3 | 0.006 | 0.004 | hein_WMM bioplex_WMM youn_WMM WMM_only |
| NCAPG2 | NCAPD2 | 0.006 | 0.003 | hein_WMM bioplex_WMM WMM_only |
| NCAPH | NCAPD3 | 0.006 | 0.012 | hein_WMM bioplex_WMM youn_WMM WMM_only |
| NCAPG2 | NCAPH | 0.006 | 0.003 | hein_WMM bioplex_WMM youn_WMM WMM_only |
| NCAPG | NCAPH2 | 0.005 | 0.011 | hein_WMM bioplex (NCAPH2) bioplex_WMM |
| NCAPH | NCAPH2 | 0.005 | 0.009 | hein_WMM bioplex (NCAPH2) bioplex_WMM |
Images
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Complex HuMAP2_02781 has an average edge precision of 0.58 which is ranked 2031 out of all 6965 complexes.
Related Complexes
| Genename | Complexes |
|---|---|
| NCAPH | HuMAP2_01363 HuMAP2_02781 |
| NCAPD2 | HuMAP2_01363 HuMAP2_02781 |
| SMC2 | HuMAP2_01363 HuMAP2_02781 HuMAP2_05812 |
| SMC4 | HuMAP2_01363 HuMAP2_02781 HuMAP2_05812 |
| NCAPG | HuMAP2_01363 HuMAP2_02781 |
| NCAPD3 | HuMAP2_01363 HuMAP2_02768 HuMAP2_02781 |
| NCAPG2 | HuMAP2_01363 HuMAP2_02768 HuMAP2_02781 |
| NCAPH2 | HuMAP2_01363 HuMAP2_02781 HuMAP2_03172 |