hu.MAP 2.0: Complex View
Human Protein Complex Map
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Complex: HuMAP2_02782
Confidence: Medium
Proteins| Genename | Protein Name | Links |
|---|---|---|
| IKZF1 | DNA-binding protein Ikaros (Ikaros family zinc finger protein 1) (Lymphoid transcription factor LyF-1) | UniProt NCBI |
| IKZF2 | Zinc finger protein Helios (Ikaros family zinc finger protein 2) | UniProt NCBI |
| HSD17B4 | Peroxisomal multifunctional enzyme type 2 (MFE-2) (17-beta-hydroxysteroid dehydrogenase 4) (17-beta-HSD 4) (D-bifunctional protein) (DBP) (Multifunctional protein 2) (MPF-2) (Short chain dehydrogenase/reductase family 8C member 1) [Cleaved into: (3R)-hydroxyacyl-CoA dehydrogenase (EC 1.1.1.n12); Enoyl-CoA hydratase 2 (EC 4.2.1.107) (EC 4.2.1.119) (3-alpha,7-alpha,12-alpha-trihydroxy-5-beta-cholest-24-enoyl-CoA hydratase)] | UniProt NCBI |
| IKZF4 | Zinc finger protein Eos (Ikaros family zinc finger protein 4) | UniProt NCBI |
| IKZF3 | Zinc finger protein Aiolos (Ikaros family zinc finger protein 3) | UniProt NCBI |
| KLHDC10 | Kelch domain-containing protein 10 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| CORUM:5441 | 0.0499726005494 | 0.166666666667 | IKZF4 | NRG1-IKZF4 complex |
Edges
| Protein 1 | Protein 2 | Score | Precision | Evidence |
|---|---|---|---|---|
| IKZF3 | IKZF4 | 1.0 | 0.949 | bioplex (IKZF3) bioplex_WMM |
| IKZF1 | IKZF4 | 0.785 | 0.756 | bioplex (IKZF1) bioplex_WMM |
| IKZF1 | IKZF2 | 0.725 | 0.735 | bioplex (IKZF1) bioplex_WMM |
| IKZF1 | IKZF3 | 0.401 | 0.561 | bioplex (IKZF1) bioplex_WMM |
| IKZF1 | KLHDC10 | 0.062 | 0.344 | bioplex (IKZF1) bioplex_WMM |
| IKZF1 | HSD17B4 | 0.02 | 0.187 | bioplex (IKZF1) bioplex_WMM |
| IKZF2 | IKZF4 | 0.01 | 0.128 | bioplex_WMM WMM_only |
| IKZF2 | IKZF3 | 0.01 | 0.128 | bioplex_WMM WMM_only |
| KLHDC10 | IKZF2 | 0.008 | 0.046 | bioplex_WMM WMM_only |
| KLHDC10 | IKZF3 | 0.008 | 0.028 | bioplex_WMM WMM_only |
| KLHDC10 | IKZF4 | 0.008 | 0.028 | bioplex_WMM WMM_only |
| IKZF2 | HSD17B4 | 0.008 | 0.025 | bioplex_WMM WMM_only |
| HSD17B4 | IKZF4 | 0.007 | 0.009 | bioplex_WMM WMM_only |
| IKZF3 | HSD17B4 | 0.007 | 0.009 | bioplex_WMM WMM_only |
| KLHDC10 | HSD17B4 | 0.007 | 0.009 | bioplex_WMM WMM_only |
Images
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Complex HuMAP2_02782 has an average edge precision of 0.263 which is ranked 5182 out of all 6965 complexes.
Related Complexes
| Genename | Complexes |
|---|---|
| IKZF1 | HuMAP2_00201 HuMAP2_02782 HuMAP2_04537 HuMAP2_06687 |
| IKZF2 | HuMAP2_00201 HuMAP2_02782 HuMAP2_04537 HuMAP2_06687 |
| HSD17B4 | HuMAP2_02782 |
| IKZF4 | HuMAP2_02782 HuMAP2_03693 HuMAP2_04537 |
| IKZF3 | HuMAP2_02782 HuMAP2_03693 HuMAP2_04537 |
| KLHDC10 | HuMAP2_00201 HuMAP2_00369 HuMAP2_00616 HuMAP2_02782 HuMAP2_04537 |