hu.MAP 2.0: Complex View
Human Protein Complex Map
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Complex: HuMAP2_02783
Confidence: Medium High
Proteins| Genename | Protein Name | Links |
|---|---|---|
| RABL6 | Rab-like protein 6 (GTP-binding protein Parf) (Partner of ARF) (Rab-like protein 1) (RBEL1) | UniProt NCBI |
| AP3S1 | AP-3 complex subunit sigma-1 (AP-3 complex subunit sigma-3A) (Adaptor-related protein complex 3 subunit sigma-1) (Clathrin-associated/assembly/adaptor protein, small 3) (Sigma-3A-adaptin) (Sigma3A-adaptin) (Sigma-adaptin 3a) | UniProt NCBI |
| RNF167 | E3 ubiquitin-protein ligase RNF167 (EC 2.3.2.27) (RING finger protein 167) (RING-type E3 ubiquitin transferase RNF167) (RING105) | UniProt NCBI |
| RNF13 | E3 ubiquitin-protein ligase RNF13 (EC 2.3.2.27) (RING finger protein 13) (RING-type E3 ubiquitin transferase RNF13) | UniProt NCBI |
| AP3M1 | AP-3 complex subunit mu-1 (AP-3 adaptor complex mu3A subunit) (Adaptor-related protein complex 3 subunit mu-1) (Mu-adaptin 3A) (Mu3A-adaptin) | UniProt NCBI |
| AP3S2 | AP-3 complex subunit sigma-2 (AP-3 complex subunit sigma-3B) (Adaptor-related protein complex 3 subunit sigma-2) (Sigma-3B-adaptin) (Sigma3B-adaptin) (Sigma-adaptin 3b) | UniProt NCBI |
| AP3B2 | AP-3 complex subunit beta-2 (Adaptor protein complex AP-3 subunit beta-2) (Adaptor-related protein complex 3 subunit beta-2) (Beta-3B-adaptin) (Clathrin assembly protein complex 3 beta-2 large chain) (Neuron-specific vesicle coat protein beta-NAP) | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| CORUM:59 | 3.17767167158e-11 | 0.571428571429 | AP3M1 AP3B2 AP3S1 AP3S2 | AP3 adaptor complex |
| CORUM:652 | 1.23769432954e-09 | 0.571428571429 | AP3M1 AP3B2 AP3S1 AP3S2 | AP3-BLOC1 complex |
| GO:0048490 | 2.02789502131e-06 | 0.571428571429 | AP3M1 AP3B2 AP3S1 AP3S2 | anterograde synaptic vesicle transport |
| GO:0099517 | 2.02789502131e-06 | 0.571428571429 | AP3M1 AP3B2 AP3S1 AP3S2 | synaptic vesicle transport along microtubule |
| GO:0099514 | 2.02789502131e-06 | 0.571428571429 | AP3M1 AP3B2 AP3S1 AP3S2 | synaptic vesicle cytoskeletal transport |
| KEGG:04142 | 6.74279515347e-06 | 0.571428571429 | AP3M1 AP3B2 AP3S1 AP3S2 | Lysosome |
| GO:0048489 | 3.94067359228e-05 | 0.571428571429 | AP3M1 AP3B2 AP3S1 AP3S2 | synaptic vesicle transport |
| GO:0008089 | 6.26817828938e-05 | 0.571428571429 | AP3M1 AP3B2 AP3S1 AP3S2 | anterograde axonal transport |
| GO:0047496 | 6.26817828938e-05 | 0.571428571429 | AP3M1 AP3B2 AP3S1 AP3S2 | vesicle transport along microtubule |
| GO:0097479 | 7.75809589829e-05 | 0.571428571429 | AP3M1 AP3B2 AP3S1 AP3S2 | synaptic vesicle localization |
| GO:0099518 | 0.000126379744832 | 0.571428571429 | AP3M1 AP3B2 AP3S1 AP3S2 | vesicle cytoskeletal trafficking |
| GO:0098930 | 0.000138393555724 | 0.571428571429 | AP3M1 AP3B2 AP3S1 AP3S2 | axonal transport |
| GO:0008088 | 0.000211763495732 | 0.571428571429 | AP3M1 AP3B2 AP3S1 AP3S2 | axo-dendritic transport |
| GO:0072384 | 0.000537283108697 | 0.571428571429 | AP3M1 AP3B2 AP3S1 AP3S2 | organelle transport along microtubule |
| GO:0010970 | 0.00921221328127 | 0.571428571429 | AP3M1 AP3B2 AP3S1 AP3S2 | transport along microtubule |
| GO:0099111 | 0.0143396670291 | 0.571428571429 | AP3M1 AP3B2 AP3S1 AP3S2 | microtubule-based transport |
| GO:0030705 | 0.0178183346517 | 0.571428571429 | AP3M1 AP3B2 AP3S1 AP3S2 | cytoskeleton-dependent intracellular transport |
| GO:0051650 | 0.0208141612097 | 0.571428571429 | AP3M1 AP3B2 AP3S1 AP3S2 | establishment of vesicle localization |
| GO:0051648 | 0.0253749350715 | 0.571428571429 | AP3M1 AP3B2 AP3S1 AP3S2 | vesicle localization |
| CORUM:2307 | 0.0499886427319 | 0.142857142857 | AP3S2 | AP3D1-AP3S2 complex |
| CORUM:2308 | 0.0499886427319 | 0.142857142857 | AP3S1 | AP3D1-AP3S1 complex |
Edges
| Protein 1 | Protein 2 | Score | Precision | Evidence |
|---|---|---|---|---|
| AP3S1 | AP3M1 | 0.988 | 0.901 | bioplex (AP3M1,AP3S1) bioplex_WMM youn_WMM gupta_WMM fraction |
| AP3S1 | AP3B2 | 0.967 | 0.877 | bioplex (AP3S1) bioplex_WMM youn_WMM |
| AP3M1 | AP3B2 | 0.922 | 0.843 | bioplex (AP3M1) bioplex_WMM youn_WMM |
| AP3S1 | RABL6 | 0.448 | 0.592 | hein_WMM bioplex (AP3S1) bioplex_WMM youn_WMM gupta_WMM |
| AP3M1 | AP3S2 | 0.427 | 0.576 | bioplex (AP3M1) bioplex_WMM youn_WMM |
| AP3S1 | RNF13 | 0.281 | 0.487 | bioplex (RNF13) bioplex_WMM |
| RNF13 | AP3S2 | 0.187 | 0.44 | bioplex (RNF13) bioplex_WMM |
| AP3M1 | RABL6 | 0.083 | 0.351 | bioplex (AP3M1) bioplex_WMM youn_WMM gupta_WMM |
| AP3S1 | RNF167 | 0.04 | 0.268 | bioplex (AP3S1) bioplex_WMM |
| AP3S1 | AP3S2 | 0.015 | 0.149 | bioplex_WMM youn_WMM WMM_only |
| RABL6 | AP3B2 | 0.009 | 0.107 | bioplex_WMM WMM_only |
| AP3B2 | AP3S2 | 0.008 | 0.069 | bioplex_WMM WMM_only |
| RABL6 | AP3S2 | 0.008 | 0.009 | bioplex_WMM youn_WMM WMM_only |
| RNF167 | AP3B2 | 0.007 | 0.01 | bioplex_WMM WMM_only |
| RABL6 | RNF167 | 0.007 | 0.009 | bioplex_WMM WMM_only |
| RNF167 | AP3S2 | 0.007 | 0.006 | bioplex_WMM WMM_only |
| AP3M1 | RNF167 | 0.007 | 0.002 | bioplex_WMM WMM_only |
| RNF167 | RNF13 | 0.007 | 0.001 | bioplex (RNF13) bioplex_WMM |
| AP3M1 | RNF13 | 0.007 | 0.009 | bioplex_WMM WMM_only |
Images
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Complex HuMAP2_02783 has an average edge precision of 0.3 which is ranked 4588 out of all 6965 complexes.
Related Complexes
| Genename | Complexes |
|---|---|
| RABL6 | HuMAP2_00924 HuMAP2_02783 HuMAP2_06447 |
| AP3S1 | HuMAP2_00924 HuMAP2_02783 HuMAP2_05936 HuMAP2_06447 |
| RNF167 | HuMAP2_00924 HuMAP2_02783 HuMAP2_06447 |
| RNF13 | HuMAP2_02783 HuMAP2_04084 HuMAP2_06447 HuMAP2_06850 |
| AP3M1 | HuMAP2_00924 HuMAP2_02783 HuMAP2_05936 HuMAP2_06447 |
| AP3S2 | HuMAP2_02783 HuMAP2_04084 HuMAP2_06447 HuMAP2_06850 |
| AP3B2 | HuMAP2_00924 HuMAP2_01887 HuMAP2_02783 HuMAP2_05936 HuMAP2_06447 |