hu.MAP 2.0: Complex View
Human Protein Complex Map
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Complex: HuMAP2_02792
Confidence: Medium
Proteins| Genename | Protein Name | Links |
|---|---|---|
| CFAP298 | Cilia- and flagella-associated protein 298 (Protein kurly homolog) | UniProt NCBI |
| KLK5 | Kallikrein-5 (EC 3.4.21.-) (Kallikrein-like protein 2) (KLK-L2) (Stratum corneum tryptic enzyme) | UniProt NCBI |
| FCSK | L-fucose kinase (Fucokinase) (EC 2.7.1.52) | UniProt NCBI |
| FLG | Filaggrin | UniProt NCBI |
| CDSN | Corneodesmosin (S protein) | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| REAC:R-HSA-6809371 | 0.0473841683248 | 0.5 | KLK5 FLG | Formation of the cornified envelope |
Edges
| Protein 1 | Protein 2 | Score | Precision | Evidence |
|---|---|---|---|---|
| CFAP298 | KLK5 | 0.04 | 0.268 | bioplex (CFAP298) bioplex_WMM |
| CFAP298 | FLG | 0.026 | 0.219 | bioplex (CFAP298) bioplex_WMM |
| FCSK | KLK5 | 0.021 | 0.188 | bioplex (KLK5) bioplex_WMM |
| CDSN | CFAP298 | 0.02 | 0.186 | bioplex (CFAP298) bioplex_WMM |
| KLK5 | FLG | 0.008 | 0.025 | bioplex_WMM WMM_only boldt_WMM |
| CDSN | FLG | 0.007 | 0.005 | bioplex_WMM WMM_only boldt_WMM |
| CDSN | KLK5 | 0.007 | 0.005 | bioplex_WMM WMM_only boldt_WMM |
Images
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Complex HuMAP2_02792 has an average edge precision of 0.128 which is ranked 6836 out of all 6965 complexes.
Related Complexes
| Genename | Complexes |
|---|---|
| CFAP298 | HuMAP2_02398 HuMAP2_02792 HuMAP2_04127 HuMAP2_04779 |
| KLK5 | HuMAP2_02398 HuMAP2_02792 HuMAP2_04127 HuMAP2_04727 HuMAP2_04779 |
| FCSK | HuMAP2_02398 HuMAP2_02792 HuMAP2_04727 |
| FLG | HuMAP2_02792 HuMAP2_02794 HuMAP2_07001 |
| CDSN | HuMAP2_00072 HuMAP2_02792 HuMAP2_05326 |