hu.MAP 2.0: Complex View
Human Protein Complex Map
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Complex: HuMAP2_02793
Confidence: Medium High
Proteins| Genename | Protein Name | Links |
|---|---|---|
| ELP5 | Elongator complex protein 5 (Dermal papilla-derived protein 6) (S-phase 2 protein) | UniProt NCBI |
| ZBTB25 | Zinc finger and BTB domain-containing protein 25 (Zinc finger protein 46) (Zinc finger protein KUP) | UniProt NCBI |
| ELP6 | Elongator complex protein 6 (Angiotonin-transactivated protein 1) (Protein TMEM103) | UniProt NCBI |
| ELP4 | Elongator complex protein 4 (hELP4) (PAX6 neighbor gene protein) | UniProt NCBI |
| PIPOX | Peroxisomal sarcosine oxidase (PSO) (EC 1.5.3.1) (EC 1.5.3.7) (L-pipecolate oxidase) (L-pipecolic acid oxidase) | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| CORUM:6332 | 2.70211703843e-08 | 0.6 | ELP5 ELP4 ELP6 | Elongator complex (ELP1, ELP2, ELP3, ELP4, ELP5, ELP6) |
| GO:0033588 | 3.17736949706e-05 | 0.6 | ELP5 ELP4 ELP6 | Elongator holoenzyme complex |
| REAC:R-HSA-3214847 | 0.00125259730234 | 0.6 | ELP5 ELP4 ELP6 | HATs acetylate histones |
| REAC:R-HSA-3247509 | 0.00849111810066 | 0.6 | ELP5 ELP4 ELP6 | Chromatin modifying enzymes |
| REAC:R-HSA-4839726 | 0.00849111810066 | 0.6 | ELP5 ELP4 ELP6 | Chromatin organization |
Edges
| Protein 1 | Protein 2 | Score | Precision | Evidence |
|---|---|---|---|---|
| ELP6 | ELP4 | 1.0 | 0.949 | bioplex (ELP6) bioplex_WMM youn_WMM gupta_WMM |
| ELP6 | ELP5 | 0.998 | 0.936 | bioplex (ELP6) bioplex_WMM youn_WMM gupta_WMM |
| PIPOX | ELP4 | 0.884 | 0.816 | bioplex (PIPOX) bioplex_WMM |
| PIPOX | ELP5 | 0.112 | 0.381 | bioplex (PIPOX) bioplex_WMM |
| ELP6 | ZBTB25 | 0.049 | 0.293 | bioplex (ELP6) bioplex_WMM |
| ELP6 | PIPOX | 0.025 | 0.215 | bioplex (PIPOX) bioplex_WMM |
| ELP4 | ELP5 | 0.013 | 0.151 | bioplex_WMM youn_WMM gupta_WMM WMM_only |
| ZBTB25 | ELP4 | 0.009 | 0.096 | bioplex_WMM WMM_only |
| ZBTB25 | ELP5 | 0.009 | 0.098 | bioplex_WMM WMM_only |
Images
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Complex HuMAP2_02793 has an average edge precision of 0.437 which is ranked 2957 out of all 6965 complexes.
Related Complexes
| Genename | Complexes |
|---|---|
| ELP5 | HuMAP2_01380 HuMAP2_02793 HuMAP2_02968 HuMAP2_03061 HuMAP2_05021 |
| ZBTB25 | HuMAP2_01380 HuMAP2_02793 HuMAP2_02968 HuMAP2_04881 |
| ELP6 | HuMAP2_01380 HuMAP2_02793 HuMAP2_02874 HuMAP2_02968 HuMAP2_03061 HuMAP2_05021 |
| ELP4 | HuMAP2_01380 HuMAP2_02662 HuMAP2_02793 HuMAP2_02874 HuMAP2_02968 |
| PIPOX | HuMAP2_01380 HuMAP2_02662 HuMAP2_02793 |