hu.MAP 2.0: Complex View
Human Protein Complex Map
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Complex: HuMAP2_02794
Confidence: Medium
Proteins| Genename | Protein Name | Links |
|---|---|---|
| NCCRP1 | F-box only protein 50 (NCC receptor protein 1 homolog) (NCCRP-1) (Non-specific cytotoxic cell receptor protein 1 homolog) | UniProt NCBI |
| ALOX12B | Arachidonate 12-lipoxygenase, 12R-type (12R-LOX) (12R-lipoxygenase) (EC 1.13.11.-) (Epidermis-type lipoxygenase 12) | UniProt NCBI |
| FLG | Filaggrin | UniProt NCBI |
| ECM1 | Extracellular matrix protein 1 (Secretory component p85) | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| HP:0011123 | 0.0114887691482 | 0.75 | FLG ALOX12B ECM1 | Inflammatory abnormality of the skin |
| HP:0011368 | 0.0162522818241 | 0.75 | FLG ALOX12B ECM1 | Epidermal thickening |
| HP:0011122 | 0.0178200083076 | 0.75 | FLG ALOX12B ECM1 | Abnormality of skin physiology |
| HP:0001072 | 0.0219842049556 | 0.75 | FLG ALOX12B ECM1 | Thickened skin |
Edges
| Protein 1 | Protein 2 | Score | Precision | Evidence |
|---|---|---|---|---|
| NCCRP1 | ECM1 | 0.038 | 0.265 | bioplex_WMM boldt boldt_WMM |
| ALOX12B | NCCRP1 | 0.036 | 0.264 | bioplex_WMM boldt boldt_WMM |
| ALOX12B | ECM1 | 0.029 | 0.233 | bioplex_WMM boldt boldt_WMM |
| FLG | NCCRP1 | 0.025 | 0.215 | bioplex_WMM boldt boldt_WMM |
| FLG | ECM1 | 0.016 | 0.164 | bioplex_WMM boldt boldt_WMM |
| FLG | ALOX12B | 0.008 | 0.081 | bioplex_WMM boldt boldt_WMM |
Images
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Complex HuMAP2_02794 has an average edge precision of 0.204 which is ranked 6129 out of all 6965 complexes.
Related Complexes
| Genename | Complexes |
|---|---|
| NCCRP1 | HuMAP2_02794 HuMAP2_03003 HuMAP2_03688 HuMAP2_05854 |
| ALOX12B | HuMAP2_02794 HuMAP2_03003 HuMAP2_03688 HuMAP2_05322 |
| FLG | HuMAP2_02792 HuMAP2_02794 HuMAP2_07001 |
| ECM1 | HuMAP2_02794 HuMAP2_03688 |