hu.MAP 2.0: Complex View

Human Protein Complex Map

Complex: HuMAP2_02799

Confidence: High

Genename	Protein Name	Links
NPLOC4	Nuclear protein localization protein 4 homolog (Protein NPL4)	UniProt NCBI
UFD1	Ubiquitin recognition factor in ER-associated degradation protein 1 (Ubiquitin fusion degradation protein 1) (UB fusion protein 1)	UniProt NCBI

Term ID	Corrected Pval	Fraction Complex Coverage	Proteins	Term Name
CORUM:6280	1.00555407742e-05	1.0	NPLOC4 UFD1	NUB1L-UFD1-NPL4-NEDD8 complex
REAC:R-HSA-110320	0.000286582912066	1.0	NPLOC4 UFD1	Translesion Synthesis by POLH
GO:0036501	0.000450823411379	1.0	NPLOC4 UFD1	UFD1-NPL4 complex
REAC:R-HSA-110313	0.00117817419405	1.0	NPLOC4 UFD1	Translesion synthesis by Y family DNA polymerases bypasses lesions on DNA template
KEGG:04141	0.00178666132548	1.0	NPLOC4 UFD1	Protein processing in endoplasmic reticulum
REAC:R-HSA-73893	0.00181167326283	1.0	NPLOC4 UFD1	DNA Damage Bypass
GO:0039536	0.00450823411379	1.0	NPLOC4 UFD1	negative regulation of RIG-I signaling pathway
GO:0034098	0.00946729163895	1.0	NPLOC4 UFD1	VCP-NPL4-UFD1 AAA ATPase complex
GO:0039532	0.0126230555186	1.0	NPLOC4 UFD1	negative regulation of viral-induced cytoplasmic pattern recognition receptor signaling pathway
GO:0039535	0.0410249304355	1.0	NPLOC4 UFD1	regulation of RIG-I signaling pathway
GO:0039529	0.0473364581948	1.0	NPLOC4 UFD1	RIG-I signaling pathway

Protein 1	Protein 2	Score	Precision	Evidence
UFD1	NPLOC4	1.0	0.949	bioplex_WMM Guru youn_WMM Malo gupta_WMM fraction

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ComplexPrecisionDistribution

Complex HuMAP2_02799 has an average edge precision of 0.949 which is ranked 5 out of all 6965 complexes.

Related Complexes

Genename	Complexes
NPLOC4	HuMAP2_02799 HuMAP2_04063 HuMAP2_06192
UFD1	HuMAP2_02054 HuMAP2_02799 HuMAP2_04063 HuMAP2_06192