hu.MAP 2.0: Complex View
Human Protein Complex Map
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Complex: HuMAP2_02812
Confidence: Medium High
Proteins| Genename | Protein Name | Links |
|---|---|---|
| FBXL16 | F-box/LRR-repeat protein 16 (F-box and leucine-rich repeat protein 16) | UniProt NCBI |
| FOXC2 | Forkhead box protein C2 (Forkhead-related protein FKHL14) (Mesenchyme fork head protein 1) (MFH-1 protein) (Transcription factor FKH-14) | UniProt NCBI |
| FOXC1 | Forkhead box protein C1 (Forkhead-related protein FKHL7) (Forkhead-related transcription factor 3) (FREAC-3) | UniProt NCBI |
| FAM214A | Protein FAM214A | UniProt NCBI |
| PPP2R2D | Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B delta isoform (PP2A subunit B isoform B55-delta) (PP2A subunit B isoform PR55-delta) (PP2A subunit B isoform R2-delta) (PP2A subunit B isoform delta) | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| WP:WP3927 | 0.00045324857597 | 0.4 | FOXC2 FOXC1 | BMP Signaling Pathway in Eyelid Development |
| WP:WP1591 | 0.00209425195703 | 0.4 | FOXC2 FOXC1 | Heart Development |
| WP:WP4657 | 0.00799132765459 | 0.4 | FOXC2 FOXC1 | 22q11.2 Deletion Syndrome |
| WP:WP2857 | 0.0271030899343 | 0.4 | FOXC2 FOXC1 | Mesodermal Commitment Pathway |
Edges
| Protein 1 | Protein 2 | Score | Precision | Evidence |
|---|---|---|---|---|
| FOXC2 | PPP2R2D | 0.695 | 0.718 | hein_WMM bioplex (PPP2R2D) bioplex_WMM |
| PPP2R2D | FAM214A | 0.206 | 0.453 | bioplex (PPP2R2D) bioplex_WMM |
| PPP2R2D | FOXC1 | 0.072 | 0.355 | hein_WMM bioplex (PPP2R2D) bioplex_WMM |
| PPP2R2D | FBXL16 | 0.047 | 0.293 | hein_WMM hein (PPP2R2D) |
| FOXC2 | FOXC1 | 0.011 | 0.144 | hein_WMM bioplex_WMM WMM_only |
| FOXC2 | FAM214A | 0.009 | 0.095 | bioplex_WMM WMM_only |
| FOXC1 | FBXL16 | 0.009 | 0.099 | hein_WMM WMM_only |
| FOXC2 | FBXL16 | 0.009 | 0.099 | hein_WMM WMM_only |
| FOXC1 | FAM214A | 0.008 | 0.029 | bioplex_WMM WMM_only |
Images
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Complex HuMAP2_02812 has an average edge precision of 0.254 which is ranked 5317 out of all 6965 complexes.
Related Complexes
| Genename | Complexes |
|---|---|
| FBXL16 | HuMAP2_02007 HuMAP2_02812 HuMAP2_03797 HuMAP2_04602 |
| FOXC2 | HuMAP2_01142 HuMAP2_02007 HuMAP2_02812 HuMAP2_03797 |
| FOXC1 | HuMAP2_02007 HuMAP2_02812 HuMAP2_03797 |
| FAM214A | HuMAP2_02007 HuMAP2_02812 HuMAP2_03797 |
| PPP2R2D | HuMAP2_01142 HuMAP2_02007 HuMAP2_02812 HuMAP2_03564 HuMAP2_03797 |