hu.MAP 2.0: Complex View
Human Protein Complex Map
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Complex: HuMAP2_02816
Confidence: Medium
Proteins| Genename | Protein Name | Links |
|---|---|---|
| FBXW7 | F-box/WD repeat-containing protein 7 (Archipelago homolog) (hAgo) (F-box and WD-40 domain-containing protein 7) (F-box protein FBX30) (SEL-10) (hCdc4) | UniProt NCBI |
| MYCBP2 | E3 ubiquitin-protein ligase MYCBP2 (EC 2.3.2.-) (Myc-binding protein 2) (Protein associated with Myc) | UniProt NCBI |
| FBXO45 | F-box/SPRY domain-containing protein 1 (F-box only protein 45) (hFbxo45) | UniProt NCBI |
| PRR36 | Proline-rich protein 36 | UniProt NCBI |
| SNX8 | Sorting nexin-8 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| CORUM:6248 | 0.0499494897235 | 0.2 | FBXW7 | FBXW7-CSF3R-GSK3B complex |
| CORUM:6975 | 0.0499494897235 | 0.2 | FBXW7 | JUN-FBW7-PRR7 complex |
Edges
| Protein 1 | Protein 2 | Score | Precision | Evidence |
|---|---|---|---|---|
| FBXW7 | PRR36 | 0.359 | 0.54 | bioplex (FBXW7) bioplex_WMM |
| FBXW7 | FBXO45 | 0.06 | 0.337 | bioplex (FBXW7) bioplex_WMM |
| FBXW7 | SNX8 | 0.042 | 0.269 | bioplex (SNX8) bioplex_WMM |
| FBXW7 | MYCBP2 | 0.03 | 0.23 | bioplex (FBXW7) bioplex_WMM |
| FBXO45 | MYCBP2 | 0.027 | 0.224 | hein_WMM bioplex_WMM boldt boldt_WMM |
| PRR36 | FBXO45 | 0.008 | 0.025 | bioplex_WMM WMM_only |
| PRR36 | MYCBP2 | 0.007 | 0.003 | bioplex_WMM WMM_only |
Images
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Complex HuMAP2_02816 has an average edge precision of 0.233 which is ranked 5649 out of all 6965 complexes.
Related Complexes
| Genename | Complexes |
|---|---|
| FBXW7 | HuMAP2_01468 HuMAP2_02816 HuMAP2_05317 |
| MYCBP2 | HuMAP2_02816 HuMAP2_03540 |
| FBXO45 | HuMAP2_01468 HuMAP2_02816 HuMAP2_05319 |
| PRR36 | HuMAP2_01468 HuMAP2_02668 HuMAP2_02816 HuMAP2_04374 HuMAP2_05317 |
| SNX8 | HuMAP2_02407 HuMAP2_02816 HuMAP2_05317 HuMAP2_06935 |