hu.MAP 2.0: Complex View
Human Protein Complex Map
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Complex: HuMAP2_02837
Confidence: Medium High
Proteins| Genename | Protein Name | Links |
|---|---|---|
| HUWE1 | E3 ubiquitin-protein ligase HUWE1 (EC 2.3.2.26) (ARF-binding protein 1) (ARF-BP1) (HECT, UBA and WWE domain-containing protein 1) (HECT-type E3 ubiquitin transferase HUWE1) (Homologous to E6AP carboxyl terminus homologous protein 9) (HectH9) (Large structure of UREB1) (LASU1) (Mcl-1 ubiquitin ligase E3) (Mule) (Upstream regulatory element-binding protein 1) (URE-B1) (URE-binding protein 1) | UniProt NCBI |
| EFTUD2 | 116 kDa U5 small nuclear ribonucleoprotein component (Elongation factor Tu GTP-binding domain-containing protein 2) (SNU114 homolog) (hSNU114) (U5 snRNP-specific protein, 116 kDa) (U5-116 kDa) | UniProt NCBI |
| DDX23 | Probable ATP-dependent RNA helicase DDX23 (EC 3.6.4.13) (100 kDa U5 snRNP-specific protein) (DEAD box protein 23) (PRP28 homolog) (U5-100kD) | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| CORUM:1335 | 0.000456110269427 | 0.666666666667 | EFTUD2 DDX23 | SNW1 complex |
| KEGG:03040 | 0.00373360278335 | 0.666666666667 | EFTUD2 DDX23 | Spliceosome |
| REAC:R-HSA-72165 | 0.008858224502 | 0.666666666667 | EFTUD2 DDX23 | mRNA Splicing - Minor Pathway |
| CORUM:1181 | 0.010043796241 | 0.666666666667 | EFTUD2 DDX23 | C complex spliceosome |
| CORUM:351 | 0.0324522040239 | 0.666666666667 | EFTUD2 DDX23 | Spliceosome |
Edges
| Protein 1 | Protein 2 | Score | Precision | Evidence |
|---|---|---|---|---|
| DDX23 | EFTUD2 | 0.998 | 0.944 | bioplex (DDX23) bioplex_WMM Guru youn_WMM Malo gupta_WMM fraction boldt_WMM treiber_WMM |
| EFTUD2 | HUWE1 | 0.162 | 0.42 | bioplex_WMM boldt youn_WMM gupta_WMM fraction boldt_WMM |
| DDX23 | HUWE1 | 0.005 | 0.009 | bioplex_WMM youn_WMM gupta_WMM fraction boldt_WMM |
Images
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Complex HuMAP2_02837 has an average edge precision of 0.458 which is ranked 2817 out of all 6965 complexes.
Related Complexes
| Genename | Complexes |
|---|---|
| HUWE1 | HuMAP2_02837 HuMAP2_03940 |
| EFTUD2 | HuMAP2_02837 HuMAP2_02954 HuMAP2_06826 |
| DDX23 | HuMAP2_00104 HuMAP2_02837 HuMAP2_04421 HuMAP2_05096 HuMAP2_06826 |