hu.MAP 2.0: Complex View
Human Protein Complex Map
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Complex: HuMAP2_02844
Confidence: High
Proteins| Genename | Protein Name | Links |
|---|---|---|
| DDAH2 | N(G),N(G)-dimethylarginine dimethylaminohydrolase 2 (DDAH-2) (Dimethylarginine dimethylaminohydrolase 2) (EC 3.5.3.18) (DDAHII) (Dimethylargininase-2) (Protein G6a) (S-phase protein) | UniProt NCBI |
| DDAH1 | N(G),N(G)-dimethylarginine dimethylaminohydrolase 1 (DDAH-1) (Dimethylarginine dimethylaminohydrolase 1) (EC 3.5.3.18) (DDAHI) (Dimethylargininase-1) | UniProt NCBI |
| EPB41L1 | Band 4.1-like protein 1 (Neuronal protein 4.1) (4.1N) | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| REAC:R-HSA-203615 | 0.000301184970683 | 0.666666666667 | DDAH2 DDAH1 | eNOS activation |
| REAC:R-HSA-202131 | 0.00060895383853 | 0.666666666667 | DDAH2 DDAH1 | Metabolism of nitric oxide: eNOS activation and regulation |
| GO:0016403 | 0.00135247023414 | 0.666666666667 | DDAH2 DDAH1 | dimethylargininase activity |
| GO:0016813 | 0.0378589948753 | 0.666666666667 | DDAH2 DDAH1 | hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines |
| GO:0000052 | 0.0378589948753 | 0.666666666667 | DDAH2 DDAH1 | citrulline metabolic process |
Edges
| Protein 1 | Protein 2 | Score | Precision | Evidence |
|---|---|---|---|---|
| DDAH1 | DDAH2 | 0.997 | 0.934 | bioplex (DDAH2) bioplex_WMM |
| DDAH2 | EPB41L1 | 0.597 | 0.667 | bioplex (DDAH2) bioplex_WMM |
| DDAH1 | EPB41L1 | 0.007 | 0.004 | bioplex_WMM WMM_only |
Images
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Complex HuMAP2_02844 has an average edge precision of 0.535 which is ranked 2305 out of all 6965 complexes.
Related Complexes
| Genename | Complexes |
|---|---|
| DDAH2 | HuMAP2_00111 HuMAP2_02844 HuMAP2_06471 |
| DDAH1 | HuMAP2_00111 HuMAP2_02844 HuMAP2_06471 HuMAP2_06892 |
| EPB41L1 | HuMAP2_02844 HuMAP2_05297 HuMAP2_06471 |