hu.MAP 2.0: Complex View
Human Protein Complex Map
Search for a protein
Complex: HuMAP2_02847
Confidence: High
Proteins| Genename | Protein Name | Links |
|---|---|---|
| ATAD5 | ATPase family AAA domain-containing protein 5 (Chromosome fragility-associated gene 1 protein) | UniProt NCBI |
| RFC1 | Replication factor C subunit 1 (Activator 1 140 kDa subunit) (A1 140 kDa subunit) (Activator 1 large subunit) (Activator 1 subunit 1) (DNA-binding protein PO-GA) (Replication factor C 140 kDa subunit) (RF-C 140 kDa subunit) (RFC140) (Replication factor C large subunit) | UniProt NCBI |
| RFC2 | Replication factor C subunit 2 (Activator 1 40 kDa subunit) (A1 40 kDa subunit) (Activator 1 subunit 2) (Replication factor C 40 kDa subunit) (RF-C 40 kDa subunit) (RFC40) | UniProt NCBI |
| RFC3 | Replication factor C subunit 3 (Activator 1 38 kDa subunit) (A1 38 kDa subunit) (Activator 1 subunit 3) (Replication factor C 38 kDa subunit) (RF-C 38 kDa subunit) (RFC38) | UniProt NCBI |
| RFC4 | Replication factor C subunit 4 (Activator 1 37 kDa subunit) (A1 37 kDa subunit) (Activator 1 subunit 4) (Replication factor C 37 kDa subunit) (RF-C 37 kDa subunit) (RFC37) | UniProt NCBI |
| RFC5 | Replication factor C subunit 5 (Activator 1 36 kDa subunit) (A1 36 kDa subunit) (Activator 1 subunit 5) (Replication factor C 36 kDa subunit) (RF-C 36 kDa subunit) (RFC36) | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| CORUM:277 | 6.09820937128e-17 | 0.833333333333 | RFC2 RFC5 RFC3 RFC4 RFC1 | RFC complex |
| CORUM:279 | 6.09820937128e-17 | 0.833333333333 | RFC2 RFC5 RFC3 RFC4 RFC1 | RFC complex |
| CORUM:2799 | 6.09820937128e-17 | 0.833333333333 | RFC2 RFC5 RFC3 RFC4 RFC1 | RFC complex |
| CORUM:2203 | 3.65872083369e-16 | 0.833333333333 | RFC2 RFC5 RFC3 RFC4 RFC1 | BRD4-RFC complex |
| CORUM:1003 | 7.6820235795e-15 | 0.833333333333 | RFC2 RFC5 RFC3 RFC4 RFC1 | RC complex (Replication competent complex) |
| GO:0005663 | 4.91515675326e-14 | 0.833333333333 | RFC2 RFC5 RFC3 RFC4 RFC1 | DNA replication factor C complex |
| REAC:R-HSA-69109 | 3.22465149775e-13 | 0.833333333333 | RFC2 RFC5 RFC3 RFC4 RFC1 | Leading Strand Synthesis |
| REAC:R-HSA-69091 | 3.22465149775e-13 | 0.833333333333 | RFC2 RFC5 RFC3 RFC4 RFC1 | Polymerase switching |
| REAC:R-HSA-174411 | 3.22465149775e-13 | 0.833333333333 | RFC2 RFC5 RFC3 RFC4 RFC1 | Polymerase switching on the C-strand of the telomere |
| CORUM:2200 | 4.54011687692e-13 | 0.666666666667 | RFC2 RFC5 RFC3 RFC4 | RFC2-5 subcomplex |
| REAC:R-HSA-110312 | 7.03481530925e-13 | 0.833333333333 | RFC2 RFC5 RFC3 RFC4 RFC1 | Translesion synthesis by REV1 |
| REAC:R-HSA-5655862 | 9.96543021746e-13 | 0.833333333333 | RFC2 RFC5 RFC3 RFC4 RFC1 | Translesion synthesis by POLK |
| REAC:R-HSA-5656121 | 9.96543021746e-13 | 0.833333333333 | RFC2 RFC5 RFC3 RFC4 RFC1 | Translesion synthesis by POLI |
| KEGG:03430 | 1.52984709694e-12 | 0.833333333333 | RFC2 RFC5 RFC3 RFC4 RFC1 | Mismatch repair |
| REAC:R-HSA-110320 | 1.87241503761e-12 | 0.833333333333 | RFC2 RFC5 RFC3 RFC4 RFC1 | Translesion Synthesis by POLH |
| CORUM:2199 | 2.26981451009e-12 | 0.666666666667 | RFC2 RFC5 RFC3 RFC4 | CHTF18-RFC2-5 complex |
| CORUM:266 | 2.26981451009e-12 | 0.666666666667 | RFC2 RFC5 RFC3 RFC4 | RAD17-RFC complex |
| CORUM:270 | 2.26981451009e-12 | 0.666666666667 | RFC2 RFC5 RFC3 RFC4 | RAD17-RFC complex |
| CORUM:2810 | 2.26981451009e-12 | 0.666666666667 | RFC2 RFC5 RFC3 RFC4 | RAD17-RFC complex |
| CORUM:2202 | 2.26981451009e-12 | 0.666666666667 | RFC2 RFC5 RFC3 RFC4 | CHTF18-RFC2-5 complex |
| CORUM:2201 | 2.26981451009e-12 | 0.666666666667 | RFC2 RFC5 RFC3 RFC4 | PCNA-RFC2-5 complex |
| REAC:R-HSA-69186 | 2.49641354248e-12 | 0.833333333333 | RFC2 RFC5 RFC3 RFC4 RFC1 | Lagging Strand Synthesis |
| REAC:R-HSA-5651801 | 3.27635923319e-12 | 0.833333333333 | RFC2 RFC5 RFC3 RFC4 RFC1 | PCNA-Dependent Long Patch Base Excision Repair |
| CORUM:2797 | 6.80871178609e-12 | 0.666666666667 | RFC2 RFC5 RFC3 RFC4 | PCNA-CHL12-RFC2-5 complex |
| REAC:R-HSA-174417 | 6.84234945834e-12 | 0.833333333333 | RFC2 RFC5 RFC3 RFC4 RFC1 | Telomere C-strand (Lagging Strand) Synthesis |
| REAC:R-HSA-5696397 | 8.55245760774e-12 | 0.833333333333 | RFC2 RFC5 RFC3 RFC4 RFC1 | Gap-filling DNA repair synthesis and ligation in GG-NER |
| REAC:R-HSA-110373 | 8.55245760774e-12 | 0.833333333333 | RFC2 RFC5 RFC3 RFC4 RFC1 | Resolution of AP sites via the multiple-nucleotide patch replacement pathway |
| CORUM:2804 | 1.58852868601e-11 | 0.666666666667 | RFC2 RFC5 RFC3 RFC4 | CTF18-cohesion-RFC complex |
| KEGG:03030 | 1.71274050852e-11 | 0.833333333333 | RFC2 RFC5 RFC3 RFC4 RFC1 | DNA replication |
| REAC:R-HSA-180786 | 2.29330899426e-11 | 0.833333333333 | RFC2 RFC5 RFC3 RFC4 RFC1 | Extension of Telomeres |
| REAC:R-HSA-110314 | 2.29330899426e-11 | 0.833333333333 | RFC2 RFC5 RFC3 RFC4 RFC1 | Recognition of DNA damage by PCNA-containing replication complex |
| REAC:R-HSA-5656169 | 2.73417670054e-11 | 0.833333333333 | RFC2 RFC5 RFC3 RFC4 RFC1 | Termination of translesion DNA synthesis |
| CORUM:3070 | 3.17671592963e-11 | 0.666666666667 | RFC2 RFC5 RFC3 RFC4 | CTF18-cohesion-RFC-POLH complex |
| CORUM:268 | 3.17671592963e-11 | 0.666666666667 | RFC2 RFC5 RFC3 RFC4 | 9-1-1-RAD17-RFC complex |
| CORUM:274 | 3.17671592963e-11 | 0.666666666667 | RFC2 RFC5 RFC3 RFC4 | 9-1-1-RAD17-RFC complex |
| REAC:R-HSA-69190 | 3.24032408461e-11 | 0.833333333333 | RFC2 RFC5 RFC3 RFC4 RFC1 | DNA strand elongation |
| WP:WP466 | 3.44835361196e-11 | 0.833333333333 | RFC2 RFC5 RFC3 RFC4 RFC1 | DNA Replication |
| KEGG:03420 | 4.9317110036e-11 | 0.833333333333 | RFC2 RFC5 RFC3 RFC4 RFC1 | Nucleotide excision repair |
| REAC:R-HSA-73933 | 5.22274747274e-11 | 0.833333333333 | RFC2 RFC5 RFC3 RFC4 RFC1 | Resolution of Abasic Sites (AP sites) |
| REAC:R-HSA-110313 | 8.07398960956e-11 | 0.833333333333 | RFC2 RFC5 RFC3 RFC4 RFC1 | Translesion synthesis by Y family DNA polymerases bypasses lesions on DNA template |
| REAC:R-HSA-5696400 | 1.20524160735e-10 | 0.833333333333 | RFC2 RFC5 RFC3 RFC4 RFC1 | Dual Incision in GG-NER |
| REAC:R-HSA-73893 | 2.46617285137e-10 | 0.833333333333 | RFC2 RFC5 RFC3 RFC4 RFC1 | DNA Damage Bypass |
| GO:0042276 | 7.61406130455e-10 | 0.833333333333 | RFC2 RFC5 RFC3 RFC4 RFC1 | error-prone translesion synthesis |
| GO:0070987 | 7.61406130455e-10 | 0.833333333333 | RFC2 RFC5 RFC3 RFC4 RFC1 | error-free translesion synthesis |
| REAC:R-HSA-6782210 | 1.22465308044e-09 | 0.833333333333 | RFC2 RFC5 RFC3 RFC4 RFC1 | Gap-filling DNA repair synthesis and ligation in TC-NER |
| REAC:R-HSA-5685942 | 1.32663300233e-09 | 0.833333333333 | RFC2 RFC5 RFC3 RFC4 RFC1 | HDR through Homologous Recombination (HRR) |
| REAC:R-HSA-6782135 | 1.32663300233e-09 | 0.833333333333 | RFC2 RFC5 RFC3 RFC4 RFC1 | Dual incision in TC-NER |
| GO:0006297 | 1.6522348647e-09 | 0.833333333333 | RFC2 RFC5 RFC3 RFC4 RFC1 | nucleotide-excision repair, DNA gap filling |
| CORUM:278 | 2.25356268047e-09 | 0.5 | RFC2 RFC4 RFC5 | RFC core complex |
| REAC:R-HSA-6781827 | 3.38820843715e-09 | 0.833333333333 | RFC2 RFC5 RFC3 RFC4 RFC1 | Transcription-Coupled Nucleotide Excision Repair (TC-NER) |
| GO:0032201 | 3.96312010577e-09 | 0.833333333333 | RFC2 RFC5 RFC3 RFC4 RFC1 | telomere maintenance via semi-conservative replication |
| REAC:R-HSA-157579 | 4.1114253941e-09 | 0.833333333333 | RFC2 RFC5 RFC3 RFC4 RFC1 | Telomere Maintenance |
| REAC:R-HSA-5696399 | 4.95311014697e-09 | 0.833333333333 | RFC2 RFC5 RFC3 RFC4 RFC1 | Global Genome Nucleotide Excision Repair (GG-NER) |
| REAC:R-HSA-73884 | 5.92723989799e-09 | 0.833333333333 | RFC2 RFC5 RFC3 RFC4 RFC1 | Base Excision Repair |
| GO:1900264 | 1.28035412092e-08 | 0.666666666667 | RFC2 RFC5 RFC3 RFC4 | positive regulation of DNA-directed DNA polymerase activity |
| GO:1900262 | 1.28035412092e-08 | 0.666666666667 | RFC2 RFC5 RFC3 RFC4 | regulation of DNA-directed DNA polymerase activity |
| REAC:R-HSA-73886 | 1.78599987084e-08 | 0.833333333333 | RFC2 RFC5 RFC3 RFC4 RFC1 | Chromosome Maintenance |
| GO:0042769 | 1.8497597492e-08 | 0.833333333333 | RFC2 RFC5 RFC3 RFC4 RFC1 | DNA damage response, detection of DNA damage |
| REAC:R-HSA-5696398 | 1.9607809034e-08 | 0.833333333333 | RFC2 RFC5 RFC3 RFC4 RFC1 | Nucleotide Excision Repair |
| GO:0006296 | 2.13866479475e-08 | 0.833333333333 | RFC2 RFC5 RFC3 RFC4 RFC1 | nucleotide-excision repair, DNA incision, 5'-to lesion |
| GO:0003689 | 2.56043303928e-08 | 0.666666666667 | RFC2 RFC5 RFC3 RFC4 | DNA clamp loader activity |
| GO:0033170 | 2.56043303928e-08 | 0.666666666667 | RFC2 RFC5 RFC3 RFC4 | protein-DNA loading ATPase activity |
| GO:0031390 | 2.56043303928e-08 | 0.666666666667 | RFC2 RFC5 RFC3 RFC4 | Ctf18 RFC-like complex |
| REAC:R-HSA-69239 | 2.80175002575e-08 | 0.833333333333 | RFC2 RFC5 RFC3 RFC4 RFC1 | Synthesis of DNA |
| GO:0033683 | 2.82455062118e-08 | 0.833333333333 | RFC2 RFC5 RFC3 RFC4 RFC1 | nucleotide-excision repair, DNA incision |
| GO:0019985 | 3.22787683477e-08 | 0.833333333333 | RFC2 RFC5 RFC3 RFC4 RFC1 | translesion synthesis |
| REAC:R-HSA-69306 | 3.90905948705e-08 | 0.833333333333 | RFC2 RFC5 RFC3 RFC4 RFC1 | DNA Replication |
| CORUM:435 | 4.50508252789e-08 | 0.5 | RFC2 RFC1 RFC4 | BASC (Ab 81) complex (BRCA1-associated genome surveillance complex) |
| REAC:R-HSA-5693567 | 4.58062236292e-08 | 0.833333333333 | RFC2 RFC5 RFC3 RFC4 RFC1 | HDR through Homologous Recombination (HRR) or Single Strand Annealing (SSA) |
| REAC:R-HSA-5693538 | 5.75788970652e-08 | 0.833333333333 | RFC2 RFC5 RFC3 RFC4 RFC1 | Homology Directed Repair |
| GO:0000731 | 6.72200990848e-08 | 0.833333333333 | RFC2 RFC5 RFC3 RFC4 RFC1 | DNA synthesis involved in DNA repair |
| REAC:R-HSA-5685938 | 7.04303391184e-08 | 0.666666666667 | RFC2 RFC5 RFC3 RFC4 | HDR through Single Strand Annealing (SSA) |
| REAC:R-HSA-176187 | 7.89588505076e-08 | 0.666666666667 | RFC2 RFC5 RFC3 RFC4 | Activation of ATR in response to replication stress |
| REAC:R-HSA-5693616 | 8.82386282266e-08 | 0.666666666667 | RFC2 RFC5 RFC3 RFC4 | Presynaptic phase of homologous DNA pairing and strand exchange |
| GO:0006301 | 1.03878083327e-07 | 0.833333333333 | RFC2 RFC5 RFC3 RFC4 RFC1 | postreplication repair |
| REAC:R-HSA-5693579 | 1.21019310036e-07 | 0.666666666667 | RFC2 RFC5 RFC3 RFC4 | Homologous DNA Pairing and Strand Exchange |
| CORUM:434 | 1.26104188141e-07 | 0.5 | RFC2 RFC1 RFC4 | BASC (Ab 80) complex (BRCA1-associated genome surveillance complex) |
| REAC:R-HSA-69242 | 1.26971687219e-07 | 0.833333333333 | RFC2 RFC5 RFC3 RFC4 RFC1 | S Phase |
| GO:0033260 | 1.27406920218e-07 | 0.833333333333 | RFC2 RFC5 RFC3 RFC4 RFC1 | nuclear DNA replication |
| REAC:R-HSA-5693532 | 1.4847948255e-07 | 0.833333333333 | RFC2 RFC5 RFC3 RFC4 RFC1 | DNA Double-Strand Break Repair |
| GO:0044786 | 1.87214020073e-07 | 0.833333333333 | RFC2 RFC5 RFC3 RFC4 RFC1 | cell cycle DNA replication |
| GO:0006260 | 3.45239368596e-07 | 1.0 | RFC3 RFC5 ATAD5 RFC4 RFC2 RFC1 | DNA replication |
| GO:0005657 | 3.73519189534e-07 | 0.833333333333 | RFC2 RFC5 RFC3 RFC4 RFC1 | replication fork |
| GO:0042623 | 3.76606909308e-07 | 1.0 | RFC3 RFC5 ATAD5 RFC4 RFC2 RFC1 | ATPase activity, coupled |
| CORUM:433 | 4.95109872097e-07 | 0.5 | RFC2 RFC1 RFC4 | BASC complex (BRCA1-associated genome surveillance complex) |
| GO:0006283 | 7.3546313708e-07 | 0.833333333333 | RFC2 RFC5 RFC3 RFC4 RFC1 | transcription-coupled nucleotide-excision repair |
| GO:0017116 | 8.69705349223e-07 | 0.666666666667 | RFC2 RFC5 RFC3 RFC4 | single-stranded DNA helicase activity |
| GO:0006275 | 1.03340357333e-06 | 0.833333333333 | RFC2 RFC5 RFC3 ATAD5 RFC4 | regulation of DNA replication |
| GO:0031391 | 1.81637152046e-06 | 0.5 | ATAD5 RFC1 RFC4 | Elg1 RFC-like complex |
| REAC:R-HSA-6804756 | 3.17671544575e-06 | 0.666666666667 | RFC2 RFC5 RFC3 RFC4 | Regulation of TP53 Activity through Phosphorylation |
| REAC:R-HSA-69473 | 3.62344030062e-06 | 0.666666666667 | RFC2 RFC5 RFC3 RFC4 | G2/M DNA damage checkpoint |
| REAC:R-HSA-5693607 | 4.11561600349e-06 | 0.666666666667 | RFC2 RFC5 RFC3 RFC4 | Processing of DNA double-strand break ends |
| GO:0016887 | 4.18840325474e-06 | 1.0 | RFC3 RFC5 ATAD5 RFC4 RFC2 RFC1 | ATPase activity |
| REAC:R-HSA-73894 | 4.35751112638e-06 | 0.833333333333 | RFC2 RFC5 RFC3 RFC4 RFC1 | DNA Repair |
| GO:0006289 | 4.71954327875e-06 | 0.833333333333 | RFC2 RFC5 RFC3 RFC4 RFC1 | nucleotide-excision repair |
| GO:0006261 | 1.24105644798e-05 | 0.833333333333 | RFC2 RFC5 RFC3 RFC4 RFC1 | DNA-dependent DNA replication |
| GO:0090305 | 1.29143311486e-05 | 0.833333333333 | RFC2 RFC5 RFC3 RFC4 RFC1 | nucleic acid phosphodiester bond hydrolysis |
| GO:0071897 | 2.26451406257e-05 | 0.833333333333 | RFC2 RFC5 RFC3 RFC4 RFC1 | DNA biosynthetic process |
| REAC:R-HSA-5633007 | 2.8747438331e-05 | 0.666666666667 | RFC2 RFC5 RFC3 RFC4 | Regulation of TP53 Activity |
| GO:0000723 | 2.88420825293e-05 | 0.833333333333 | RFC2 RFC5 RFC3 RFC4 RFC1 | telomere maintenance |
| GO:0090329 | 2.99853000209e-05 | 0.666666666667 | RFC2 RFC5 RFC3 RFC4 | regulation of DNA-dependent DNA replication |
| GO:0051606 | 3.18810892015e-05 | 0.833333333333 | RFC2 RFC5 RFC3 RFC4 RFC1 | detection of stimulus |
| REAC:R-HSA-69481 | 3.68471857477e-05 | 0.666666666667 | RFC2 RFC5 RFC3 RFC4 | G2/M Checkpoints |
| GO:0032200 | 4.39080435103e-05 | 0.833333333333 | RFC2 RFC5 RFC3 RFC4 RFC1 | telomere organization |
| REAC:R-HSA-69278 | 4.68016887558e-05 | 0.833333333333 | RFC2 RFC5 RFC3 RFC4 RFC1 | Cell Cycle, Mitotic |
| REAC:R-HSA-1640170 | 0.000115024964847 | 0.833333333333 | RFC2 RFC5 RFC3 RFC4 RFC1 | Cell Cycle |
| GO:2000573 | 0.000143725346999 | 0.666666666667 | RFC2 RFC5 RFC3 RFC4 | positive regulation of DNA biosynthetic process |
| GO:0003678 | 0.000143725346999 | 0.666666666667 | RFC2 RFC5 RFC3 RFC4 | DNA helicase activity |
| WP:WP2446 | 0.000157102141644 | 0.5 | RFC5 RFC3 RFC4 | Retinoblastoma Gene in Cancer |
| GO:0017111 | 0.000163127930271 | 1.0 | RFC3 RFC5 ATAD5 RFC4 RFC2 RFC1 | nucleoside-triphosphatase activity |
| GO:0016462 | 0.000244464978835 | 1.0 | RFC3 RFC5 ATAD5 RFC4 RFC2 RFC1 | pyrophosphatase activity |
| GO:0016818 | 0.000249285868072 | 1.0 | RFC3 RFC5 ATAD5 RFC4 RFC2 RFC1 | hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides |
| GO:0016817 | 0.000249285868072 | 1.0 | RFC3 RFC5 ATAD5 RFC4 RFC2 RFC1 | hydrolase activity, acting on acid anhydrides |
| REAC:R-HSA-69620 | 0.000322105305692 | 0.666666666667 | RFC2 RFC5 RFC3 RFC4 | Cell Cycle Checkpoints |
| CORUM:1004 | 0.000653133016722 | 0.333333333333 | RFC2 RFC1 | RC complex during S-phase of cell cycle |
| CORUM:1005 | 0.000653133016722 | 0.333333333333 | RFC2 RFC1 | RC complex during G2/M-phase of cell cycle |
| GO:0060249 | 0.000693957239919 | 0.833333333333 | RFC2 RFC5 RFC3 RFC4 RFC1 | anatomical structure homeostasis |
| REAC:R-HSA-3700989 | 0.000694220165361 | 0.666666666667 | RFC2 RFC5 RFC3 RFC4 | Transcriptional Regulation by TP53 |
| GO:2000278 | 0.00084563217517 | 0.666666666667 | RFC2 RFC5 RFC3 RFC4 | regulation of DNA biosynthetic process |
| GO:0004386 | 0.000926409268263 | 0.666666666667 | RFC2 RFC5 RFC3 RFC4 | helicase activity |
| GO:0008094 | 0.00101282970404 | 0.666666666667 | RFC2 RFC5 RFC3 RFC4 | DNA-dependent ATPase activity |
| WP:WP2363 | 0.00180854165103 | 0.333333333333 | RFC3 RFC4 | Gastric Cancer Network 2 |
| GO:0061860 | 0.00676235117068 | 0.333333333333 | ATAD5 RFC1 | DNA clamp unloader activity |
| GO:0090618 | 0.00676235117068 | 0.333333333333 | ATAD5 RFC1 | DNA clamp unloading |
| GO:0006281 | 0.00761654730624 | 0.833333333333 | RFC2 RFC5 RFC3 RFC4 RFC1 | DNA repair |
| GO:0051054 | 0.00769760366442 | 0.666666666667 | RFC2 RFC5 RFC3 RFC4 | positive regulation of DNA metabolic process |
| GO:0022402 | 0.00779587445301 | 1.0 | RFC3 RFC5 ATAD5 RFC4 RFC2 RFC1 | cell cycle process |
| GO:1901796 | 0.00970139563937 | 0.666666666667 | RFC2 RFC5 RFC3 RFC4 | regulation of signal transduction by p53 class mediator |
| GO:0140097 | 0.0135624164426 | 0.666666666667 | RFC2 RFC5 RFC3 RFC4 | catalytic activity, acting on DNA |
| GO:0044427 | 0.0151552637177 | 1.0 | RFC3 RFC5 ATAD5 RFC4 RFC2 RFC1 | chromosomal part |
| GO:0003677 | 0.0183905219298 | 1.0 | RFC3 RFC5 ATAD5 RFC4 RFC2 RFC1 | DNA binding |
| GO:0005694 | 0.0188325821521 | 1.0 | RFC3 RFC5 ATAD5 RFC4 RFC2 RFC1 | chromosome |
| GO:0007049 | 0.0218766736595 | 1.0 | RFC3 RFC5 ATAD5 RFC4 RFC2 RFC1 | cell cycle |
| GO:0019725 | 0.0240712813761 | 0.833333333333 | RFC2 RFC5 RFC3 RFC4 RFC1 | cellular homeostasis |
| GO:0072331 | 0.0412709918798 | 0.666666666667 | RFC2 RFC5 RFC3 RFC4 | signal transduction by p53 class mediator |
| CORUM:1132 | 0.0499726005494 | 0.166666666667 | RFC4 | RFC2-RIalpha complex |
| CORUM:1131 | 0.0499726005494 | 0.166666666667 | RFC2 | RFC2-RIalpha complex |
Edges
| Protein 1 | Protein 2 | Score | Precision | Evidence |
|---|---|---|---|---|
| RFC3 | RFC5 | 1.0 | 0.949 | hein_WMM bioplex (RFC5) bioplex_WMM Guru youn_WMM Malo fraction treiber_WMM |
| RFC2 | RFC4 | 1.0 | 0.949 | hein_WMM bioplex (RFC4) bioplex_WMM Guru youn_WMM Malo gupta_WMM fraction boldt_WMM treiber_WMM |
| RFC5 | RFC4 | 1.0 | 0.949 | hein_WMM bioplex (RFC4,RFC5) bioplex_WMM Guru youn_WMM Malo gupta_WMM fraction treiber_WMM |
| RFC3 | RFC4 | 1.0 | 0.949 | hein_WMM bioplex (RFC4) bioplex_WMM Guru boldt youn_WMM Malo gupta_WMM fraction boldt_WMM treiber_WMM |
| RFC2 | RFC3 | 1.0 | 0.949 | hein_WMM bioplex_WMM Guru youn_WMM Malo gupta_WMM fraction boldt_WMM treiber_WMM |
| RFC2 | RFC5 | 0.999 | 0.948 | hein_WMM bioplex (RFC5) bioplex_WMM Guru youn_WMM Malo fraction treiber_WMM |
| RFC1 | RFC5 | 0.988 | 0.901 | hein_WMM bioplex (RFC5) bioplex_WMM Guru youn_WMM fraction |
| RFC3 | RFC1 | 0.936 | 0.85 | hein_WMM bioplex_WMM Guru youn_WMM fraction |
| RFC4 | ATAD5 | 0.894 | 0.819 | hein_WMM bioplex (RFC4) bioplex_WMM youn_WMM gupta_WMM |
| RFC1 | RFC4 | 0.619 | 0.675 | hein_WMM bioplex (RFC4) bioplex_WMM Guru youn_WMM fraction |
| RFC5 | ATAD5 | 0.133 | 0.406 | hein_WMM bioplex (RFC5) bioplex_WMM youn_WMM |
| RFC2 | RFC1 | 0.098 | 0.357 | hein_WMM bioplex_WMM Guru youn_WMM fraction |
| RFC1 | ATAD5 | 0.016 | 0.159 | hein_WMM bioplex_WMM youn_WMM fraction |
| RFC2 | ATAD5 | 0.011 | 0.144 | hein_WMM bioplex_WMM youn_WMM WMM_only |
| RFC3 | ATAD5 | 0.003 | 0.009 | hein_WMM bioplex_WMM youn_WMM fraction |
Images
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Complex HuMAP2_02847 has an average edge precision of 0.668 which is ranked 1534 out of all 6965 complexes.
Related Complexes
| Genename | Complexes |
|---|---|
| ATAD5 | HuMAP2_00874 HuMAP2_02712 HuMAP2_02847 HuMAP2_05133 |
| RFC1 | HuMAP2_00430 HuMAP2_00874 HuMAP2_02847 HuMAP2_03572 |
| RFC2 | HuMAP2_00430 HuMAP2_00874 HuMAP2_02712 HuMAP2_02847 |
| RFC3 | HuMAP2_00430 HuMAP2_00874 HuMAP2_02712 HuMAP2_02847 |
| RFC4 | HuMAP2_00874 HuMAP2_02712 HuMAP2_02847 HuMAP2_05133 |
| RFC5 | HuMAP2_00430 HuMAP2_00874 HuMAP2_02712 HuMAP2_02847 |