hu.MAP 2.0: Complex View
Human Protein Complex Map
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Complex: HuMAP2_02860
Confidence: Medium
Proteins| Genename | Protein Name | Links |
|---|---|---|
| BUD23 | Probable 18S rRNA (guanine-N(7))-methyltransferase (EC 2.1.1.-) (Bud site selection protein 23 homolog) (Metastasis-related methyltransferase 1) (Williams-Beuren syndrome chromosomal region 22 protein) (rRNA methyltransferase and ribosome maturation factor) | UniProt NCBI |
| TRMT112 | Multifunctional methyltransferase subunit TRM112-like protein (tRNA methyltransferase 112 homolog) | UniProt NCBI |
| TRMT11 | tRNA (guanine(10)-N2)-methyltransferase homolog (EC 2.1.1.-) (tRNA guanosine-2'-O-methyltransferase TRM11 homolog) | UniProt NCBI |
| ASS1 | Argininosuccinate synthase (EC 6.3.4.5) (Citrulline--aspartate ligase) | UniProt NCBI |
| PFKM | ATP-dependent 6-phosphofructokinase, muscle type (ATP-PFK) (PFK-M) (EC 2.7.1.11) (6-phosphofructokinase type A) (Phosphofructo-1-kinase isozyme A) (PFK-A) (Phosphohexokinase) | UniProt NCBI |
| GALC | Galactocerebrosidase (GALCERase) (EC 3.2.1.46) (Galactocerebroside beta-galactosidase) (Galactosylceramidase) (Galactosylceramide beta-galactosidase) | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| GO:0070476 | 0.00676235117068 | 0.333333333333 | BUD23 TRMT112 | rRNA (guanine-N7)-methylation |
| KEGG:01230 | 0.0153684049392 | 0.333333333333 | ASS1 PFKM | Biosynthesis of amino acids |
| REAC:R-HSA-6782315 | 0.0180541440856 | 0.333333333333 | TRMT11 TRMT112 | tRNA modification in the nucleus and cytosol |
| GO:0036265 | 0.020283420769 | 0.333333333333 | BUD23 TRMT112 | RNA (guanine-N7)-methylation |
| REAC:R-HSA-6790901 | 0.0388379782234 | 0.333333333333 | BUD23 TRMT112 | rRNA modification in the nucleus and cytosol |
Edges
| Protein 1 | Protein 2 | Score | Precision | Evidence |
|---|---|---|---|---|
| BUD23 | TRMT112 | 0.373 | 0.546 | hein_WMM bioplex (BUD23) bioplex_WMM fraction |
| TRMT112 | TRMT11 | 0.134 | 0.405 | bioplex (TRMT11) bioplex_WMM boldt_WMM |
| TRMT11 | GALC | 0.108 | 0.373 | bioplex (TRMT11) bioplex_WMM |
| TRMT11 | PFKM | 0.038 | 0.263 | bioplex (TRMT11) bioplex_WMM youn_WMM fraction |
| ASS1 | PFKM | 0.023 | 0.208 | youn_WMM gupta_WMM fraction |
| TRMT112 | GALC | 0.007 | 0.013 | bioplex_WMM WMM_only |
| TRMT11 | ASS1 | 0.007 | 0.005 | youn_WMM gupta_WMM WMM_only |
| BUD23 | PFKM | 0.007 | 0.005 | bioplex_WMM WMM_only |
| TRMT112 | PFKM | 0.007 | 0.003 | bioplex_WMM youn_WMM WMM_only |
| TRMT112 | ASS1 | 0.007 | 0.001 | youn_WMM WMM_only |
| GALC | PFKM | 0.007 | 0.003 | bioplex_WMM WMM_only |
Images
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Complex HuMAP2_02860 has an average edge precision of 0.166 which is ranked 6569 out of all 6965 complexes.
Related Complexes
| Genename | Complexes |
|---|---|
| BUD23 | HuMAP2_01108 HuMAP2_01987 HuMAP2_02860 |
| TRMT112 | HuMAP2_01108 HuMAP2_01987 HuMAP2_02860 |
| TRMT11 | HuMAP2_01987 HuMAP2_02860 HuMAP2_04989 |
| ASS1 | HuMAP2_02860 HuMAP2_03597 HuMAP2_04905 HuMAP2_05668 HuMAP2_05911 |
| PFKM | HuMAP2_02860 HuMAP2_04569 HuMAP2_05288 HuMAP2_05668 HuMAP2_06807 |
| GALC | HuMAP2_01987 HuMAP2_02860 HuMAP2_04989 |