hu.MAP 2.0: Complex View
Human Protein Complex Map
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Complex: HuMAP2_02881
Confidence: Medium
Proteins| Genename | Protein Name | Links |
|---|---|---|
| STXBP5L | Syntaxin-binding protein 5-like (Lethal(2) giant larvae protein homolog 4) (Tomosyn-2) | UniProt NCBI |
| STXBP2 | Syntaxin-binding protein 2 (Protein unc-18 homolog 2) (Unc18-2) (Protein unc-18 homolog B) (Unc-18B) | UniProt NCBI |
| VAMP3 | Vesicle-associated membrane protein 3 (VAMP-3) (Cellubrevin) (CEB) (Synaptobrevin-3) | UniProt NCBI |
| VAMP8 | Vesicle-associated membrane protein 8 (VAMP-8) (Endobrevin) (EDB) | UniProt NCBI |
| STX19 | Syntaxin-19 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| KEGG:04130 | 4.27757362181e-06 | 0.6 | VAMP8 STX19 VAMP3 | SNARE interactions in vesicular transport |
| GO:0031201 | 1.98600319243e-05 | 0.8 | VAMP8 STXBP5L VAMP3 STX19 | SNARE complex |
| CORUM:874 | 4.0241279111e-05 | 0.4 | VAMP8 VAMP3 | SNARE complex (VAMP3, VAMP4, VAMP8, STX6) |
| CORUM:1169 | 4.0241279111e-05 | 0.4 | VAMP8 VAMP3 | SNARE complex (STX4, VAMP8, VAMP3, SNAP23) |
| GO:0006887 | 0.0117213357889 | 1.0 | STX19 VAMP8 STXBP5L VAMP3 STXBP2 | exocytosis |
| GO:0140029 | 0.0156368617465 | 0.6 | VAMP8 STX19 VAMP3 | exocytic process |
| REAC:R-HSA-1236974 | 0.0443461879505 | 0.4 | VAMP8 VAMP3 | ER-Phagosome pathway |
Edges
| Protein 1 | Protein 2 | Score | Precision | Evidence |
|---|---|---|---|---|
| STXBP2 | STX19 | 0.929 | 0.845 | bioplex (STX19) bioplex_WMM |
| STXBP5L | STX19 | 0.659 | 0.696 | bioplex (STX19) bioplex_WMM |
| VAMP3 | STX19 | 0.096 | 0.359 | bioplex (STX19) bioplex_WMM |
| VAMP8 | STX19 | 0.085 | 0.349 | bioplex (STX19) bioplex_WMM |
| VAMP3 | VAMP8 | 0.011 | 0.144 | bioplex_WMM gupta_WMM WMM_only |
| STXBP2 | VAMP8 | 0.01 | 0.1 | bioplex_WMM gupta_WMM WMM_only |
| VAMP8 | STXBP5L | 0.009 | 0.111 | bioplex_WMM WMM_only |
| STXBP2 | STXBP5L | 0.008 | 0.089 | bioplex_WMM WMM_only |
| VAMP3 | STXBP5L | 0.008 | 0.083 | bioplex_WMM WMM_only |
| VAMP3 | STXBP2 | 0.008 | 0.066 | bioplex_WMM gupta_WMM WMM_only |
Images
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Complex HuMAP2_02881 has an average edge precision of 0.284 which is ranked 4822 out of all 6965 complexes.
Related Complexes