hu.MAP 2.0: Complex View
Human Protein Complex Map
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Complex: HuMAP2_02884
Confidence: Very High
Proteins| Genename | Protein Name | Links |
|---|---|---|
| SUPT20H | Transcription factor SPT20 homolog (p38-interacting protein) (p38IP) | UniProt NCBI |
| KAT2A | Histone acetyltransferase KAT2A (EC 2.3.1.48) (General control of amino acid synthesis protein 5-like 2) (Histone acetyltransferase GCN5) (hGCN5) (Histone succinyltransferase KAT2A) (EC 2.3.1.-) (Lysine acetyltransferase 2A) (STAF97) | UniProt NCBI |
| TADA3 | Transcriptional adapter 3 (ADA3 homolog) (hADA3) (STAF54) (Transcriptional adapter 3-like) (ADA3-like protein) | UniProt NCBI |
| TADA2A | Transcriptional adapter 2-alpha (Transcriptional adapter 2-like) (ADA2-like protein) | UniProt NCBI |
| SUPT7L | STAGA complex 65 subunit gamma (Adenocarcinoma antigen ART1) (SPTF-associated factor 65 gamma) (STAF65gamma) (Suppressor of Ty 7-like) | UniProt NCBI |
| TADA2B | Transcriptional adapter 2-beta (ADA2-like protein beta) (ADA2-beta) | UniProt NCBI |
| SGF29 | SAGA-associated factor 29 (Coiled-coil domain-containing protein 101) (SAGA complex-associated factor 29) | UniProt NCBI |
| MBIP | MAP3K12-binding inhibitory protein 1 (MAPK upstream kinase-binding inhibitory protein) (MUK-binding inhibitory protein) | UniProt NCBI |
| YEATS2 | YEATS domain-containing protein 2 | UniProt NCBI |
| TAF6L | TAF6-like RNA polymerase II p300/CBP-associated factor-associated factor 65 kDa subunit 6L (PCAF-associated factor 65-alpha) (PAF65-alpha) | UniProt NCBI |
| ZZZ3 | ZZ-type zinc finger-containing protein 3 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| CORUM:6657 | 8.31147118312e-20 | 0.636363636364 | KAT2A SGF29 TADA3 TADA2A ZZZ3 MBIP YEATS2 | ATAC complex, GCN5-linked |
| CORUM:6665 | 2.37484553467e-18 | 0.636363636364 | KAT2A SGF29 TADA3 TADA2A ZZZ3 MBIP YEATS2 | ATAC complex, YEATS2-linked |
| REAC:R-HSA-3214847 | 1.07693680723e-17 | 0.909090909091 | KAT2A SGF29 SUPT7L SUPT20H TADA2B TADA3 ZZZ3 MBIP YEATS2 TAF6L | HATs acetylate histones |
| CORUM:6664 | 2.20005831911e-17 | 0.636363636364 | KAT2A SGF29 SUPT7L SUPT20H TADA2B TADA3 TAF6L | STAGA complex, SPT3-linked |
| CORUM:6643 | 3.48260619849e-17 | 0.636363636364 | KAT2A SGF29 SUPT7L SUPT20H TADA2B TADA3 TAF6L | SAGA complex, GCN5-linked |
| GO:0000123 | 5.01594501148e-15 | 0.818181818182 | KAT2A SGF29 SUPT7L SUPT20H TADA2B TADA3 MBIP YEATS2 TAF6L | histone acetyltransferase complex |
| REAC:R-HSA-4839726 | 7.42509974522e-15 | 0.909090909091 | KAT2A SGF29 SUPT7L SUPT20H TADA2B TADA3 ZZZ3 MBIP YEATS2 TAF6L | Chromatin organization |
| REAC:R-HSA-3247509 | 7.42509974522e-15 | 0.909090909091 | KAT2A SGF29 SUPT7L SUPT20H TADA2B TADA3 ZZZ3 MBIP YEATS2 TAF6L | Chromatin modifying enzymes |
| GO:1902493 | 1.56959325735e-14 | 0.818181818182 | KAT2A SGF29 SUPT7L SUPT20H TADA2B TADA3 MBIP YEATS2 TAF6L | acetyltransferase complex |
| GO:0031248 | 1.56959325735e-14 | 0.818181818182 | KAT2A SGF29 SUPT7L SUPT20H TADA2B TADA3 MBIP YEATS2 TAF6L | protein acetyltransferase complex |
| GO:0070461 | 2.45178628506e-13 | 0.636363636364 | KAT2A SGF29 SUPT7L SUPT20H TADA2B TADA3 TAF6L | SAGA-type complex |
| GO:0016573 | 4.40682624074e-11 | 0.727272727273 | KAT2A SGF29 SUPT7L TADA2B TADA3 MBIP YEATS2 TAF6L | histone acetylation |
| GO:0043966 | 5.06464425371e-11 | 0.636363636364 | KAT2A SGF29 SUPT7L TAF6L TADA3 MBIP YEATS2 | histone H3 acetylation |
| GO:0018393 | 5.13450152913e-11 | 0.727272727273 | KAT2A SGF29 SUPT7L TADA2B TADA3 MBIP YEATS2 TAF6L | internal peptidyl-lysine acetylation |
| GO:0006475 | 7.43118359937e-11 | 0.727272727273 | KAT2A SGF29 SUPT7L TADA2B TADA3 MBIP YEATS2 TAF6L | internal protein amino acid acetylation |
| GO:0018394 | 7.98534648201e-11 | 0.727272727273 | KAT2A SGF29 SUPT7L TADA2B TADA3 MBIP YEATS2 TAF6L | peptidyl-lysine acetylation |
| GO:0006473 | 5.97989040739e-10 | 0.727272727273 | KAT2A SGF29 SUPT7L TADA2B TADA3 MBIP YEATS2 TAF6L | protein acetylation |
| GO:0043543 | 3.40715838496e-09 | 0.727272727273 | KAT2A SGF29 SUPT7L TADA2B TADA3 MBIP YEATS2 TAF6L | protein acylation |
| CORUM:476 | 5.37623706953e-09 | 0.363636363636 | TAF6L KAT2A SUPT7L TADA3 | STAGA complex |
| CORUM:475 | 5.37623706953e-09 | 0.363636363636 | TAF6L KAT2A SUPT7L TADA3 | STAGA complex |
| GO:0005671 | 7.55403690183e-09 | 0.454545454545 | KAT2A MBIP YEATS2 SGF29 TADA3 | Ada2/Gcn5/Ada3 transcription activator complex |
| GO:0018205 | 1.31645704034e-07 | 0.727272727273 | KAT2A SGF29 SUPT7L TADA2B TADA3 MBIP YEATS2 TAF6L | peptidyl-lysine modification |
| GO:0016570 | 3.67828290332e-07 | 0.727272727273 | KAT2A SGF29 SUPT7L TADA2B TADA3 MBIP YEATS2 TAF6L | histone modification |
| GO:0016569 | 5.28318758427e-07 | 0.727272727273 | KAT2A SGF29 SUPT7L TADA2B TADA3 MBIP YEATS2 TAF6L | covalent chromatin modification |
| CORUM:6641 | 1.13325345233e-06 | 0.272727272727 | KAT2A TADA2B TADA3 | USP22-SAGA complex |
| CORUM:471 | 2.42644341986e-06 | 0.272727272727 | TADA3 TAF6L TADA2A | PCAF complex |
| CORUM:477 | 2.42644341986e-06 | 0.272727272727 | TADA3 TAF6L TADA2A | PCAF complex |
| GO:0030914 | 2.64968960261e-06 | 0.363636363636 | TAF6L KAT2A SUPT7L TADA3 | STAGA complex |
| GO:1990234 | 2.65527121969e-06 | 0.818181818182 | KAT2A SGF29 SUPT7L SUPT20H TADA2B TADA3 MBIP YEATS2 TAF6L | transferase complex |
| GO:1902562 | 2.80210849534e-06 | 0.454545454545 | KAT2A MBIP YEATS2 SGF29 TADA3 | H4 histone acetyltransferase complex |
| CORUM:0000000 | 6.27334655689e-06 | 1.0 | KAT2A SGF29 SUPT7L SUPT20H TADA2B TADA3 ZZZ3 MBIP YEATS2 TADA2A TAF6L | CORUM root |
| CORUM:456 | 9.18173987688e-06 | 0.272727272727 | KAT2A TAF6L TADA3 | TFTC complex (TATA-binding protein-free TAF-II-containing complex) |
| CORUM:462 | 9.18173987688e-06 | 0.272727272727 | KAT2A TAF6L TADA3 | TFTC complex (TATA-binding protein-free TAF-II-containing complex) |
| CORUM:455 | 9.18173987688e-06 | 0.272727272727 | KAT2A TAF6L TADA3 | TFTC complex (TATA-binding protein-free TAF-II-containing complex) |
| CORUM:445 | 9.18173987688e-06 | 0.272727272727 | KAT2A TAF6L TADA3 | TFTC complex (TATA-binding protein-free TAF-II-containing complex) |
| CORUM:470 | 1.12960481308e-05 | 0.272727272727 | KAT2A TAF6L TADA3 | TFTC complex (TATA-binding protein-free TAF-II-containing complex) |
| CORUM:513 | 1.12960481308e-05 | 0.272727272727 | KAT2A TAF6L TADA3 | TFTC complex (TATA-binding protein-free TAF-II-containing complex) |
| GO:0004402 | 1.42109238268e-05 | 0.454545454545 | TADA2B KAT2A TAF6L SUPT7L TADA3 | histone acetyltransferase activity |
| GO:0061733 | 1.70354452215e-05 | 0.454545454545 | TADA2B KAT2A TAF6L SUPT7L TADA3 | peptide-lysine-N-acetyltransferase activity |
| GO:0044451 | 3.06839766151e-05 | 0.818181818182 | KAT2A SGF29 SUPT7L SUPT20H TADA2B TADA3 MBIP YEATS2 TAF6L | nucleoplasm part |
| GO:0034212 | 3.57966484748e-05 | 0.454545454545 | TADA2B KAT2A TAF6L SUPT7L TADA3 | peptide N-acetyltransferase activity |
| GO:0006325 | 3.85617892229e-05 | 0.727272727273 | KAT2A SGF29 SUPT7L TADA2B TADA3 MBIP YEATS2 TAF6L | chromatin organization |
| GO:0008080 | 7.29871758239e-05 | 0.454545454545 | TADA2B KAT2A TAF6L SUPT7L TADA3 | N-acetyltransferase activity |
| GO:0016410 | 0.000161642621208 | 0.454545454545 | TADA2B KAT2A TAF6L SUPT7L TADA3 | N-acyltransferase activity |
| GO:0016407 | 0.000224355935586 | 0.454545454545 | TADA2B KAT2A TAF6L SUPT7L TADA3 | acetyltransferase activity |
| GO:1902494 | 0.00031759147892 | 0.818181818182 | KAT2A SGF29 SUPT7L SUPT20H TADA2B TADA3 MBIP YEATS2 TAF6L | catalytic complex |
| GO:0018193 | 0.000968479999498 | 0.727272727273 | KAT2A SGF29 SUPT7L TADA2B TADA3 MBIP YEATS2 TAF6L | peptidyl-amino acid modification |
| CORUM:438 | 0.0015050021591 | 0.181818181818 | KAT2A TADA3 | GCN5-TRRAP histone acetyltransferase complex |
| GO:0051276 | 0.00153765416377 | 0.727272727273 | KAT2A SGF29 SUPT7L TADA2B TADA3 MBIP YEATS2 TAF6L | chromosome organization |
| GO:0000124 | 0.0024645761864 | 0.272727272727 | TADA3 SGF29 SUPT20H | SAGA complex |
| GO:0016747 | 0.00592810412069 | 0.454545454545 | TADA2B KAT2A TAF6L SUPT7L TADA3 | transferase activity, transferring acyl groups other than amino-acyl groups |
| GO:0016746 | 0.0106648885039 | 0.454545454545 | TADA2B KAT2A TAF6L SUPT7L TADA3 | transferase activity, transferring acyl groups |
| GO:0140110 | 0.0169050558197 | 0.727272727273 | KAT2A SGF29 SUPT7L TADA2B TADA3 ZZZ3 YEATS2 TAF6L | transcription regulator activity |
| GO:0003713 | 0.045242423357 | 0.454545454545 | TADA2B KAT2A TAF6L SUPT7L TADA3 | transcription coactivator activity |
Edges
| Protein 1 | Protein 2 | Score | Precision | Evidence |
|---|---|---|---|---|
| SGF29 | TADA3 | 1.0 | 0.949 | hein_WMM bioplex (SGF29,TADA3) bioplex_WMM Guru youn_WMM hein (SGF29) Malo fraction boldt_WMM |
| ZZZ3 | MBIP | 0.999 | 0.949 | hein_WMM bioplex (MBIP) bioplex_WMM youn_WMM |
| MBIP | YEATS2 | 0.999 | 0.949 | hein_WMM bioplex (MBIP) bioplex_WMM youn_WMM |
| SGF29 | SUPT20H | 0.994 | 0.919 | hein_WMM bioplex (SGF29) bioplex_WMM youn_WMM hein (SGF29) boldt_WMM |
| SGF29 | TADA2B | 0.987 | 0.901 | hein_WMM bioplex (SGF29,TADA2B) bioplex_WMM youn_WMM hein (SGF29) boldt_WMM |
| MBIP | TADA2A | 0.987 | 0.901 | hein_WMM bioplex (MBIP) bioplex_WMM |
| SGF29 | SUPT7L | 0.986 | 0.901 | hein_WMM bioplex (SGF29) bioplex_WMM youn_WMM hein (SGF29) boldt_WMM |
| KAT2A | SGF29 | 0.981 | 0.897 | hein_WMM bioplex (SGF29) bioplex_WMM hein (SGF29) boldt_WMM |
| SUPT7L | TADA2B | 0.98 | 0.896 | hein_WMM bioplex (TADA2B) bioplex_WMM youn_WMM boldt_WMM |
| SUPT20H | TADA2B | 0.977 | 0.892 | hein_WMM bioplex (TADA2B) bioplex_WMM youn_WMM boldt_WMM |
| SGF29 | TADA2A | 0.972 | 0.885 | hein_WMM bioplex (SGF29) bioplex_WMM hein (SGF29) |
| SGF29 | YEATS2 | 0.969 | 0.881 | hein_WMM bioplex (SGF29) bioplex_WMM youn_WMM hein (SGF29) gupta_WMM |
| TADA3 | TADA2A | 0.963 | 0.871 | hein_WMM bioplex (TADA3) bioplex_WMM |
| KAT2A | TADA3 | 0.962 | 0.87 | hein_WMM bioplex (TADA3) bioplex_WMM boldt_WMM |
| TADA3 | MBIP | 0.946 | 0.857 | hein_WMM bioplex (MBIP,TADA3) bioplex_WMM youn_WMM |
| TADA3 | YEATS2 | 0.895 | 0.821 | hein_WMM bioplex (TADA3) bioplex_WMM youn_WMM |
| TADA3 | TADA2B | 0.881 | 0.815 | hein_WMM bioplex (TADA2B,TADA3) bioplex_WMM youn_WMM boldt_WMM |
| SGF29 | MBIP | 0.872 | 0.804 | hein_WMM bioplex (MBIP,SGF29) bioplex_WMM youn_WMM hein (SGF29) |
| SGF29 | ZZZ3 | 0.871 | 0.804 | hein_WMM bioplex (SGF29) bioplex_WMM youn_WMM hein (SGF29) |
| TADA3 | ZZZ3 | 0.818 | 0.773 | hein_WMM bioplex (TADA3) bioplex_WMM youn_WMM |
| SGF29 | TAF6L | 0.782 | 0.755 | hein_WMM bioplex (SGF29,TAF6L) bioplex_WMM boldt youn_WMM hein (SGF29) boldt_WMM |
| SUPT20H | TADA3 | 0.742 | 0.74 | hein_WMM bioplex (TADA3) bioplex_WMM youn_WMM boldt_WMM |
| TAF6L | TADA2B | 0.734 | 0.738 | hein_WMM bioplex (TADA2B,TAF6L) bioplex_WMM youn_WMM boldt_WMM |
| KAT2A | MBIP | 0.585 | 0.663 | hein_WMM bioplex (MBIP) bioplex_WMM |
| TAF6L | SUPT7L | 0.327 | 0.516 | hein_WMM bioplex (TAF6L) bioplex_WMM youn_WMM boldt_WMM |
| TADA3 | SUPT7L | 0.318 | 0.51 | hein_WMM bioplex (TADA3) bioplex_WMM youn_WMM boldt_WMM |
| SUPT20H | TAF6L | 0.103 | 0.365 | hein_WMM bioplex (TAF6L) bioplex_WMM youn_WMM boldt_WMM |
| ZZZ3 | YEATS2 | 0.086 | 0.351 | hein_WMM bioplex_WMM youn_WMM WMM_only |
| SUPT20H | SUPT7L | 0.039 | 0.266 | hein_WMM bioplex_WMM youn_WMM WMM_only boldt_WMM |
| TAF6L | TADA3 | 0.027 | 0.232 | hein_WMM bioplex (TADA3,TAF6L) bioplex_WMM youn_WMM boldt_WMM |
| KAT2A | TAF6L | 0.027 | 0.225 | hein_WMM bioplex (TAF6L) bioplex_WMM boldt_WMM |
| ZZZ3 | TADA2A | 0.025 | 0.211 | hein_WMM bioplex_WMM WMM_only |
| YEATS2 | TADA2A | 0.021 | 0.194 | hein_WMM bioplex_WMM WMM_only |
| KAT2A | TADA2A | 0.021 | 0.184 | hein_WMM bioplex_WMM WMM_only |
| KAT2A | YEATS2 | 0.016 | 0.161 | hein_WMM bioplex_WMM WMM_only |
| KAT2A | ZZZ3 | 0.016 | 0.154 | hein_WMM bioplex_WMM WMM_only |
| KAT2A | TADA2B | 0.013 | 0.144 | hein_WMM bioplex_WMM WMM_only boldt_WMM |
| KAT2A | SUPT7L | 0.013 | 0.151 | hein_WMM bioplex_WMM WMM_only boldt_WMM |
| KAT2A | SUPT20H | 0.013 | 0.155 | hein_WMM bioplex_WMM WMM_only boldt_WMM |
| TADA2A | TADA2B | 0.01 | 0.122 | hein_WMM bioplex_WMM WMM_only |
| TADA2A | SUPT7L | 0.009 | 0.112 | hein_WMM bioplex_WMM WMM_only |
| SUPT20H | TADA2A | 0.009 | 0.113 | hein_WMM bioplex_WMM WMM_only |
| MBIP | TADA2B | 0.009 | 0.108 | hein_WMM bioplex_WMM youn_WMM WMM_only |
| ZZZ3 | TADA2B | 0.009 | 0.108 | hein_WMM bioplex_WMM youn_WMM WMM_only |
| ZZZ3 | SUPT7L | 0.009 | 0.089 | hein_WMM bioplex_WMM youn_WMM WMM_only |
| MBIP | SUPT7L | 0.009 | 0.096 | hein_WMM bioplex_WMM youn_WMM WMM_only |
| SUPT20H | ZZZ3 | 0.009 | 0.101 | hein_WMM bioplex_WMM youn_WMM WMM_only |
| SUPT20H | MBIP | 0.009 | 0.099 | hein_WMM bioplex_WMM youn_WMM WMM_only |
| YEATS2 | SUPT7L | 0.009 | 0.095 | hein_WMM bioplex_WMM youn_WMM WMM_only |
| YEATS2 | TADA2B | 0.008 | 0.087 | hein_WMM bioplex_WMM youn_WMM WMM_only |
| SUPT20H | YEATS2 | 0.008 | 0.089 | hein_WMM bioplex_WMM youn_WMM WMM_only |
| TAF6L | TADA2A | 0.008 | 0.082 | hein_WMM bioplex_WMM WMM_only |
| TAF6L | YEATS2 | 0.008 | 0.046 | hein_WMM bioplex_WMM youn_WMM gupta_WMM WMM_only |
| TAF6L | ZZZ3 | 0.007 | 0.008 | hein_WMM bioplex_WMM youn_WMM WMM_only |
| TAF6L | MBIP | 0.006 | 0.003 | hein_WMM bioplex (MBIP) bioplex_WMM youn_WMM |
Images
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Complex HuMAP2_02884 has an average edge precision of 0.466 which is ranked 2753 out of all 6965 complexes.
Related Complexes