hu.MAP 2.0: Complex View
Human Protein Complex Map
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Complex: HuMAP2_02895
Confidence: Medium High
Proteins| Genename | Protein Name | Links |
|---|---|---|
| RARS2 | Probable arginine--tRNA ligase, mitochondrial (EC 6.1.1.19) (Arginyl-tRNA synthetase) (ArgRS) | UniProt NCBI |
| AASS | Alpha-aminoadipic semialdehyde synthase, mitochondrial (LKR/SDH) [Includes: Lysine ketoglutarate reductase (LKR) (LOR) (EC 1.5.1.8); Saccharopine dehydrogenase (SDH) (EC 1.5.1.9)] | UniProt NCBI |
| ACADM | Medium-chain specific acyl-CoA dehydrogenase, mitochondrial (MCAD) (EC 1.3.8.7) | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| HP:0000750 | 0.0197046749414 | 1.0 | RARS2 AASS ACADM | Delayed speech and language development |
| WP:WP4228 | 0.0285649389616 | 0.333333333333 | AASS | Vitamin B6-dependent and responsive disorders |
Edges
| Protein 1 | Protein 2 | Score | Precision | Evidence |
|---|---|---|---|---|
| AASS | ACADM | 0.13 | 0.399 | bioplex_WMM Guru youn_WMM fraction |
| AASS | RARS2 | 0.049 | 0.293 | bioplex (RARS2) bioplex_WMM boldt youn_WMM boldt_WMM |
| RARS2 | ACADM | 0.006 | 0.002 | bioplex (RARS2) bioplex_WMM youn_WMM treiber_WMM |
Images
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Complex HuMAP2_02895 has an average edge precision of 0.231 which is ranked 5671 out of all 6965 complexes.
Related Complexes
| Genename | Complexes |
|---|---|
| RARS2 | HuMAP2_02895 HuMAP2_04255 HuMAP2_04882 HuMAP2_06671 |
| AASS | HuMAP2_01636 HuMAP2_02487 HuMAP2_02895 HuMAP2_06671 |
| ACADM | HuMAP2_02895 HuMAP2_04444 HuMAP2_04924 HuMAP2_06529 |