hu.MAP 2.0: Complex View
Human Protein Complex Map
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Complex: HuMAP2_02898
Confidence: Medium High
Proteins| Genename | Protein Name | Links |
|---|---|---|
| RNF41 | E3 ubiquitin-protein ligase NRDP1 (EC 2.3.2.27) (RING finger protein 41) (RING-type E3 ubiquitin transferase NRDP1) | UniProt NCBI |
| LCP1 | Plastin-2 (L-plastin) (LC64P) (Lymphocyte cytosolic protein 1) (LCP-1) | UniProt NCBI |
| STIM1 | Stromal interaction molecule 1 | UniProt NCBI |
| PLS1 | Plastin-1 (Intestine-specific plastin) (I-plastin) | UniProt NCBI |
| METTL6 | Methyltransferase-like protein 6 (EC 2.1.1.-) | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| MIRNA:hsa-miR-6783-5p | 0.00422733627308 | 0.6 | RNF41 METTL6 STIM1 | hsa-miR-6783-5p |
| MIRNA:hsa-miR-6824-5p | 0.0235413326705 | 0.4 | RNF41 METTL6 | hsa-miR-6824-5p |
| CORUM:6108 | 0.0249780992026 | 0.2 | STIM1 | STIM1-TRPV4 complex |
Edges
| Protein 1 | Protein 2 | Score | Precision | Evidence |
|---|---|---|---|---|
| METTL6 | PLS1 | 0.328 | 0.517 | bioplex (METTL6) bioplex_WMM |
| METTL6 | STIM1 | 0.26 | 0.482 | bioplex (METTL6) bioplex_WMM |
| PLS1 | LCP1 | 0.201 | 0.451 | bioplex (LCP1) bioplex_WMM youn_WMM gupta_WMM treiber_WMM |
| RNF41 | LCP1 | 0.044 | 0.274 | bioplex (LCP1) bioplex_WMM |
| STIM1 | LCP1 | 0.007 | 0.001 | gupta_WMM WMM_only |
| RNF41 | PLS1 | 0.007 | 0.004 | bioplex_WMM WMM_only |
| STIM1 | PLS1 | 0.007 | 0.003 | bioplex_WMM youn_WMM WMM_only |
Images
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Complex HuMAP2_02898 has an average edge precision of 0.247 which is ranked 5414 out of all 6965 complexes.
Related Complexes