hu.MAP 2.0: Complex View
Human Protein Complex Map
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Complex: HuMAP2_02899
Confidence: Medium High
Proteins| Genename | Protein Name | Links |
|---|---|---|
| NAT10 | RNA cytidine acetyltransferase (EC 2.3.1.-) (18S rRNA cytosine acetyltransferase) (N-acetyltransferase 10) (N-acetyltransferase-like protein) (hALP) | UniProt NCBI |
| RRP9 | U3 small nucleolar RNA-interacting protein 2 (RRP9 homolog) (U3 small nucleolar ribonucleoprotein-associated 55 kDa protein) (U3 snoRNP-associated 55 kDa protein) (U3-55K) | UniProt NCBI |
| DDX18 | ATP-dependent RNA helicase DDX18 (EC 3.6.4.13) (DEAD box protein 18) (Myc-regulated DEAD box protein) (MrDb) | UniProt NCBI |
| SRPK1 | SRSF protein kinase 1 (EC 2.7.11.1) (SFRS protein kinase 1) (Serine/arginine-rich protein-specific kinase 1) (SR-protein-specific kinase 1) | UniProt NCBI |
| SRPK2 | SRSF protein kinase 2 (EC 2.7.11.1) (SFRS protein kinase 2) (Serine/arginine-rich protein-specific kinase 2) (SR-protein-specific kinase 2) [Cleaved into: SRSF protein kinase 2 N-terminal; SRSF protein kinase 2 C-terminal] | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| GO:0022613 | 0.000460710313953 | 1.0 | SRPK2 RRP9 NAT10 DDX18 SRPK1 | ribonucleoprotein complex biogenesis |
| GO:0006396 | 0.0184779947673 | 1.0 | SRPK2 RRP9 NAT10 DDX18 SRPK1 | RNA processing |
| REAC:R-HSA-6790901 | 0.0237053784759 | 0.4 | NAT10 RRP9 | rRNA modification in the nucleus and cytosol |
| WP:WP411 | 0.0254557044772 | 0.4 | SRPK1 SRPK2 | mRNA Processing |
Edges
| Protein 1 | Protein 2 | Score | Precision | Evidence |
|---|---|---|---|---|
| NAT10 | SRPK1 | 0.109 | 0.377 | hein_WMM bioplex_WMM Guru youn_WMM gupta_WMM fraction treiber_WMM |
| SRPK1 | SRPK2 | 0.064 | 0.348 | bioplex_WMM boldt youn_WMM boldt_WMM |
| RRP9 | DDX18 | 0.049 | 0.296 | bioplex_WMM youn_WMM gupta_WMM fraction treiber_WMM |
| DDX18 | NAT10 | 0.041 | 0.268 | hein_WMM bioplex_WMM Guru youn_WMM gupta_WMM fraction treiber_WMM |
| NAT10 | SRPK2 | 0.006 | 0.006 | bioplex_WMM youn_WMM WMM_only treiber_WMM |
| DDX18 | SRPK1 | 0.006 | 0.008 | hein_WMM bioplex_WMM youn_WMM gupta_WMM WMM_only treiber_WMM |
| RRP9 | NAT10 | 0.005 | 0.01 | bioplex_WMM youn_WMM gupta_WMM WMM_only |
| RRP9 | SRPK2 | 0.005 | 0.007 | bioplex_WMM youn_WMM WMM_only |
| RRP9 | SRPK1 | 0.005 | 0.013 | bioplex_WMM youn_WMM WMM_only treiber_WMM |
| DDX18 | SRPK2 | 0.004 | 0.009 | bioplex_WMM Guru youn_WMM fraction treiber_WMM |
Images
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Complex HuMAP2_02899 has an average edge precision of 0.134 which is ranked 6808 out of all 6965 complexes.
Related Complexes