hu.MAP 2.0: Complex View
Human Protein Complex Map
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Complex: HuMAP2_02909
Confidence: Medium
Proteins| Genename | Protein Name | Links |
|---|---|---|
| TTK | Dual specificity protein kinase TTK (EC 2.7.12.1) (Phosphotyrosine picked threonine-protein kinase) (PYT) | UniProt NCBI |
| C5AR2 | C5a anaphylatoxin chemotactic receptor 2 (Complement component 5a receptor 2) (G-protein coupled receptor 77) | UniProt NCBI |
| ABHD17A | Alpha/beta hydrolase domain-containing protein 17A (Abhydrolase domain-containing protein 17A) (EC 3.1.2.22) | UniProt NCBI |
| LPAR6 | Lysophosphatidic acid receptor 6 (LPA receptor 6) (LPA-6) (Oleoyl-L-alpha-lysophosphatidic acid receptor) (P2Y purinoceptor 5) (P2Y5) (Purinergic receptor 5) (RB intron encoded G-protein coupled receptor) | UniProt NCBI |
| BMP7 | Bone morphogenetic protein 7 (BMP-7) (Osteogenic protein 1) (OP-1) (Eptotermin alfa) | UniProt NCBI |
| PTPN1 | Tyrosine-protein phosphatase non-receptor type 1 (EC 3.1.3.48) (Protein-tyrosine phosphatase 1B) (PTP-1B) | UniProt NCBI |
| GSTCD | Glutathione S-transferase C-terminal domain-containing protein | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| WP:WP455 | 0.0468514080623 | 0.285714285714 | LPAR6 C5AR2 | GPCRs, Class A Rhodopsin-like |
Edges
| Protein 1 | Protein 2 | Score | Precision | Evidence |
|---|---|---|---|---|
| PTPN1 | C5AR2 | 0.073 | 0.356 | bioplex (C5AR2) bioplex_WMM |
| GSTCD | C5AR2 | 0.039 | 0.264 | bioplex (C5AR2) bioplex_WMM |
| BMP7 | GSTCD | 0.031 | 0.239 | bioplex () bioplex_WMM |
| ABHD17A | C5AR2 | 0.025 | 0.211 | bioplex (C5AR2) bioplex_WMM |
| LPAR6 | ABHD17A | 0.023 | 0.209 | bioplex (LPAR6) bioplex_WMM |
| TTK | C5AR2 | 0.021 | 0.188 | bioplex (C5AR2) bioplex_WMM |
| ABHD17A | TTK | 0.008 | 0.044 | bioplex_WMM WMM_only |
| ABHD17A | GSTCD | 0.007 | 0.01 | bioplex_WMM WMM_only |
| ABHD17A | PTPN1 | 0.007 | 0.003 | bioplex_WMM WMM_only |
| TTK | GSTCD | 0.007 | 0.005 | bioplex_WMM youn_WMM gupta_WMM WMM_only |
| PTPN1 | GSTCD | 0.007 | 0.001 | bioplex_WMM WMM_only |
| TTK | BMP7 | 0.007 | 0.003 | bioplex_WMM WMM_only |
| PTPN1 | TTK | 0.006 | 0.003 | bioplex_WMM youn_WMM gupta_WMM WMM_only |
Images
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Complex HuMAP2_02909 has an average edge precision of 0.118 which is ranked 6881 out of all 6965 complexes.
Related Complexes
| Genename | Complexes |
|---|---|
| TTK | HuMAP2_02909 |
| C5AR2 | HuMAP2_02909 HuMAP2_04148 HuMAP2_06249 |
| ABHD17A | HuMAP2_01183 HuMAP2_01932 HuMAP2_02909 HuMAP2_06863 |
| LPAR6 | HuMAP2_00771 HuMAP2_01932 HuMAP2_02909 |
| BMP7 | HuMAP2_02909 HuMAP2_05381 HuMAP2_05909 |
| PTPN1 | HuMAP2_02201 HuMAP2_02909 HuMAP2_06249 |
| GSTCD | HuMAP2_02909 HuMAP2_04148 HuMAP2_05823 HuMAP2_05909 |