hu.MAP 2.0: Complex View
Human Protein Complex Map
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Complex: HuMAP2_02918
Confidence: Medium High
Proteins| Genename | Protein Name | Links |
|---|---|---|
| HIP1R | Huntingtin-interacting protein 1-related protein (HIP1-related protein) (Huntingtin-interacting protein 12) (HIP-12) | UniProt NCBI |
| USP24 | Ubiquitin carboxyl-terminal hydrolase 24 (EC 3.4.19.12) (Deubiquitinating enzyme 24) (Ubiquitin thioesterase 24) (Ubiquitin-specific-processing protease 24) | UniProt NCBI |
| EBF3 | Transcription factor COE3 (Early B-cell factor 3) (EBF-3) (Olf-1/EBF-like 2) (O/E-2) (OE-2) | UniProt NCBI |
| HIP1 | Huntingtin-interacting protein 1 (HIP-1) (Huntingtin-interacting protein I) (HIP-I) | UniProt NCBI |
| CPNE2 | Copine-2 (Copine II) | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| GO:2000588 | 0.00450823411379 | 0.4 | HIP1 HIP1R | positive regulation of platelet-derived growth factor receptor-beta signaling pathway |
| GO:0010641 | 0.0270421395626 | 0.4 | HIP1 HIP1R | positive regulation of platelet-derived growth factor receptor signaling pathway |
| GO:0032051 | 0.0450641792523 | 0.4 | HIP1 HIP1R | clathrin light chain binding |
| GO:2000586 | 0.0450641792523 | 0.4 | HIP1 HIP1R | regulation of platelet-derived growth factor receptor-beta signaling pathway |
| CORUM:1130 | 0.0499494897235 | 0.2 | HIP1R | Hip1R-cortactin complex |
Edges
| Protein 1 | Protein 2 | Score | Precision | Evidence |
|---|---|---|---|---|
| HIP1 | CPNE2 | 0.426 | 0.575 | bioplex (CPNE2) bioplex_WMM |
| USP24 | CPNE2 | 0.064 | 0.348 | bioplex (CPNE2) bioplex_WMM |
| HIP1 | HIP1R | 0.041 | 0.27 | hein_WMM bioplex (HIP1R) bioplex_WMM |
| CPNE2 | EBF3 | 0.041 | 0.268 | bioplex (CPNE2) bioplex_WMM |
| HIP1 | EBF3 | 0.008 | 0.06 | bioplex_WMM WMM_only |
| HIP1 | USP24 | 0.008 | 0.012 | bioplex_WMM WMM_only |
| USP24 | EBF3 | 0.008 | 0.012 | bioplex_WMM WMM_only |
| HIP1R | USP24 | 0.007 | 0.003 | bioplex_WMM youn_WMM WMM_only |
Images
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Complex HuMAP2_02918 has an average edge precision of 0.194 which is ranked 6267 out of all 6965 complexes.
Related Complexes
| Genename | Complexes |
|---|---|
| HIP1R | HuMAP2_00186 HuMAP2_02918 HuMAP2_04182 HuMAP2_06718 |
| USP24 | HuMAP2_00855 HuMAP2_02918 |
| EBF3 | HuMAP2_01406 HuMAP2_02918 HuMAP2_04338 HuMAP2_06752 |
| HIP1 | HuMAP2_00186 HuMAP2_01406 HuMAP2_02918 HuMAP2_04182 HuMAP2_06718 HuMAP2_06752 |
| CPNE2 | HuMAP2_01406 HuMAP2_02918 HuMAP2_06752 |